2020
Treatment strategies in ischaemic left ventricular dysfunction: a network meta-analysis
Gaudino M, Hameed I, Khan FM, Tam DY, Rahouma M, Yongle R, Naik A, Di Franco A, Demetres M, Petrie MC, Jolicoeur EM, Girardi LN, Fremes SE. Treatment strategies in ischaemic left ventricular dysfunction: a network meta-analysis. European Journal Of Cardio-Thoracic Surgery 2020, 59: 293-301. PMID: 33085752, DOI: 10.1093/ejcts/ezaa319.Peer-Reviewed Original ResearchPercutaneous coronary interventionIschemic left ventricular systolic dysfunctionMedical therapyCardiac deathMyocardial infarctionRevascularization strategyHigh mortalityLeft ventricular systolic dysfunctionIschemic left ventricular dysfunctionLeft ventricular ejection fractionBest revascularization strategyLower cardiac deathOptimal revascularization strategyCoronary artery bypassVentricular systolic dysfunctionLeft ventricular dysfunctionVentricular ejection fractionDrug-eluting stentsRelative treatment effectsArtery bypassSystolic dysfunctionVentricular dysfunctionCoronary interventionSecondary outcomesEjection fraction
2019
Impact of left ventricular ejection fraction on the outcomes of open repair of descending thoracic and thoracoabdominal aneurysms
Gambardella I, Gaudino MFL, Rahouma M, Farrington WJ, Khan FM, Hameed I, Lau C, Iannacone E, Girardi LN. Impact of left ventricular ejection fraction on the outcomes of open repair of descending thoracic and thoracoabdominal aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2019, 161: 534-541.e5. PMID: 31924362, DOI: 10.1016/j.jtcvs.2019.11.009.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionDepressed left ventricular ejection fractionVentricular ejection fractionCubic spline analysisOperative mortalityIndependent predictorsAdverse eventsEjection fractionWorse long-term survivalRisk of MAEThoracoabdominal aneurysm repairWorse preoperative profilesMajor adverse eventsSpline analysisLong-term survivalTAAA repairThoracoabdominal aneurysmsOpen repairAneurysm repairThoracic aneurysmCox regressionPreoperative profilesMortalityMultivariate regressionPatients