Featured Publications
Assessing the effectiveness of COVID-19 vaccines in Pakistan: A test-negative case-control study
Nisar M, Ansari N, Malik A, Shahid S, Lalani K, Chandna M, Younus A, Hasan Z, Khan U, Khalid F, Mahesar M, Farrukh Qazi M, Yildirim I, Jehan F, Omer S. Assessing the effectiveness of COVID-19 vaccines in Pakistan: A test-negative case-control study. Journal Of Infection 2023, 86: e144-e147. PMID: 36708775, PMCID: PMC9876011, DOI: 10.1016/j.jinf.2023.01.016.Peer-Reviewed Original Research
2021
A Retrospective Test-Negative Case-Control Study to Evaluate Influenza Vaccine Effectiveness in Preventing Hospitalizations in Children
Yildirim I, Kao CM, Tippett A, Suntarattiwong P, Munye M, Yi J, Elmontser M, Quincer E, Focht C, Watson N, Bilen H, Baker JM, Lopman B, Hogenesch E, Rostad CA, Anderson EJ. A Retrospective Test-Negative Case-Control Study to Evaluate Influenza Vaccine Effectiveness in Preventing Hospitalizations in Children. Clinical Infectious Diseases 2021, 73: 1759-1767. PMID: 34410341, PMCID: PMC8599178, DOI: 10.1093/cid/ciab709.Peer-Reviewed Original ResearchConceptsInfluenza vaccine effectivenessInfluenza-positive casesInfluenza-related hospitalizationsVaccine effectivenessInfluenza seasonOdds ratioInfluenza ALaboratory-confirmed influenza-related hospitalizationsTest-negative case-control study designAdjusted vaccine effectivenessInfluenza-negative controlsTest-negative controlsCase-control study designHospitalization of childrenTest-negative casesConfidence intervalsNon-Hispanic blacksLogistic regression modelsPreventing HospitalizationInfluenza vaccinationInfluenza burdenMedian ageInfluenza B.Influenza infectionPediatric hospitalizations
2020
The burden of respiratory syncytial virus infections among children with sickle cell disease
Rostad CA, Maillis AN, Lai K, Bakshi N, Jerris RC, Lane PA, Yee ME, Yildirim I. The burden of respiratory syncytial virus infections among children with sickle cell disease. Pediatric Blood & Cancer 2020, 68: e28759. PMID: 33034160, PMCID: PMC8246443, DOI: 10.1002/pbc.28759.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusSickle cell diseaseRespiratory viral panelRSV-positive casesRSV infectionAnnual incidenceHospitalization ratesCell diseaseBurden of RSVPediatric lower respiratory tract infectionsLaboratory-confirmed RSV infectionRespiratory syncytial virus infectionRSV-related hospitalization rateLower respiratory tract infectionsRSV positive testRSV-negative childrenRSV-negative patientsAcute chest syndromeSyncytial virus infectionRespiratory tract infectionsAverage annual incidenceMultivariate logistic regressionConfidence intervalsCase-control studyOutcome of childrenUrinary Tract Infections With Extended-spectrum-β-lactamase-producing Bacteria: Case-control Study.
Amin O, Prestel C, Gonzalez MD, Lyon T, Shane A, Jaggi P, Tippett A, Yildirim I. Urinary Tract Infections With Extended-spectrum-β-lactamase-producing Bacteria: Case-control Study. The Pediatric Infectious Disease Journal 2020, 39: 211-216. PMID: 32032306, DOI: 10.1097/inf.0000000000002531.Peer-Reviewed Original ResearchConceptsUrinary tract infectionESBL-producing bacteriaCase-control studyRisk factorsTract infectionsPrior intensive care unit admissionIntensive care unit admissionPediatric urinary tract infectionCause of UTIClinical signs/symptomsCare unit admissionIndependent risk factorYear of diagnosisΒ-lactamase-producing bacteriaSigns/symptomsCommon bacterial infectionsSpectrum β-lactamasesRational antimicrobial useESBL casesESBL-UTIUnit admissionUnderlying comorbiditiesPrior hospitalizationEmpirical therapyPediatric patients
2016
Influenza Vaccine Effectiveness: A Glass Both Half Full and Half Empty
Omer SB, Yildirim I. Influenza Vaccine Effectiveness: A Glass Both Half Full and Half Empty. Clinical Infectious Diseases 2016, 63: ciw637. PMID: 27702767, DOI: 10.1093/cid/ciw637.Peer-Reviewed Original Research