1986
Dietary potassium modulates active potassium absorption and secretion in rat distal colon
Foster E, Sandle G, Hayslett J, Binder H. Dietary potassium modulates active potassium absorption and secretion in rat distal colon. American Journal Of Physiology 1986, 251: g619-g626. PMID: 3022598, DOI: 10.1152/ajpgi.1986.251.5.g619.Peer-Reviewed Original ResearchConceptsNet potassium absorptionNet potassium secretionPotassium secretionDistal colonic mucosaPotassium-loaded ratsRat distal colonPotassium transportActive potassium absorptionDietary potassiumPotassium absorptionColonic mucosaDistal colonMucosal amilorideLarge intestinePotassium depletionBody storesActive potassium transportSecretionBathing solutionPotassium loadingGroupK fluxesMucosaColonControlSodium and chloride transport in the large intestine of potassium-loaded rats
Budinger M, Foster E, Hayslett J, Binder H. Sodium and chloride transport in the large intestine of potassium-loaded rats. American Journal Of Physiology 1986, 251: g249-g252. PMID: 2426972, DOI: 10.1152/ajpgi.1986.251.2.g249.Peer-Reviewed Original ResearchConceptsPotassium secretionSodium absorptionRat distal colonic mucosaElectroneutral sodium chloride absorptionPotassium loadingNa-K-ATPase activityElectrogenic sodium absorptionDistal colonic mucosaActive potassium secretionPotassium-loaded ratsNet sodium absorptionSodium chloride absorptionActive sodium transportVoltage-clamp conditionsDietary potassiumColonic functionColonic mucosaNet chloride fluxNet sodium fluxJNanetNet sodiumLarge intestineChloride fluxSodium transportIdentical increase
1985
The electrical basis for enhanced potassium secretion in rat distal colon during dietary potassium loading
Sandle G, Foster E, Lewis S, Binder H, Hayslett J. The electrical basis for enhanced potassium secretion in rat distal colon during dietary potassium loading. Pflügers Archiv - European Journal Of Physiology 1985, 403: 433-439. PMID: 2409517, DOI: 10.1007/bf00589258.Peer-Reviewed Original ResearchConceptsRat distal colonDistal colonPotassium secretionDietary potassium loadingPotassium channel blocker tetraethylammonium chlorideBasolateral membrane voltageChannel blocker tetraethylammonium chloridePotassium loadingSodium channel blocker amilorideActive potassium secretionElectrical basisEnhanced potassium secretionChannel blocker amilorideMembrane conductanceIntracellular potassium activityApical membrane resistanceMucosal additionPotassium-selective microelectrodesBasal conditionsControl tissuesTransepithelial voltageColonMembrane voltageSecretionTetraethylammonium chlorideRole of Aldosterone and Dietary Potassium in Potassium Adaptation in the Distal Colon of the Rat
Foster E, Jones W, Hayslett J, Binder H. Role of Aldosterone and Dietary Potassium in Potassium Adaptation in the Distal Colon of the Rat. Gastroenterology 1985, 88: 41-46. PMID: 3964771, DOI: 10.1016/s0016-5085(85)80130-x.Peer-Reviewed Original ResearchConceptsPotassium-enriched dietChronic potassium loadingNet potassium secretionAldosterone levelsDietary potassiumPotassium adaptationNet potassium transportPotassium secretionAldosterone-independent mechanismsBasal aldosterone levelsPotassium-loaded animalsRole of aldosteronePotassium loadingInfusion of aldosteroneDistal colonic mucosaEffects of aldosteroneIntact adrenal glandsNet potassium absorptionPotassium transportAdrenal glandDistal colonColonic mucosaIntact ratsAdrenalectomized animalsExperimental rats
1982
Mechanism of potassium adaptation
Hayslett J, Binder H. Mechanism of potassium adaptation. American Journal Of Physiology 1982, 243: f103-f112. PMID: 7051849, DOI: 10.1152/ajprenal.1982.243.2.f103.Peer-Reviewed Original ResearchConceptsPotassium secretionPotassium adaptationChronic renal insufficiencyNa-K-ATPase activityAdministration of glucocorticoidsPotassium loadingNa-K-ATPaseTransepithelial potential differenceRenal insufficiencyPotassium excretionColonic mucosaExcretory loadDietary potassium loadingDistal nephronLarge intestinePotassium homeostasisDietary loadingElevated levelsPotassium pumpBasolateral portionEpitheliumCellular changesDistal portionSecretionBasolateral cell membrane