2017
Placental 11 β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) expression very early during human pregnancy
Salvante KG, Milano K, Kliman HJ, Nepomnaschy PA. Placental 11 β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) expression very early during human pregnancy. Journal Of Developmental Origins Of Health And Disease 2017, 8: 149-154. PMID: 28112069, DOI: 10.1017/s2040174416000611.Peer-Reviewed Original ResearchConceptsProtective roleHydroxysteroid dehydrogenase type 2Intra-uterine growth restrictionType 2 expressionUterine endometrial glandsCritical protective roleDehydrogenase type 2Maternal-fetal exchangeHypothesized protective roleColumnar epithelial cellsGlucocorticoid exposureEndometrial glandsHuman pregnancyBirth weightGrowth restrictionCortisol exposurePlacental expressionBioactive cortisolHuman fetusesType 2Postnatal developmentPhysiologic stressEpithelial cellsImmunocytochemical analysisDevelopmental outcomesLuteal start vaginal micronized progesterone improves pregnancy success in women with recurrent pregnancy loss
Stephenson MD, McQueen D, Winter M, Kliman HJ. Luteal start vaginal micronized progesterone improves pregnancy success in women with recurrent pregnancy loss. Fertility And Sterility 2017, 107: 684-690.e2. PMID: 28081870, DOI: 10.1016/j.fertnstert.2016.11.029.Peer-Reviewed Original ResearchConceptsPregnancy successEndometrial biopsySubsequent pregnancyLH surgePregnancy lossVaginal micronized progesteroneObservational cohort studyUnexplained pregnancy lossRecurrent pregnancy lossCohort of womenCyclin E expressionMicronized progesteronePrior pregnancyCohort studyOngoing pregnancyConcomitant findingsEndometrial glandsOdds ratioInclusion criteriaMAIN OUTCOMEPregnancyE expressionWomenCohortWeeks
2009
Abnormal nuclear cyclin E expression in endometrial glands of patients with recurrent pregnancy loss (RPL): response to vaginal micronized progesterone adminstration
Stephenson M, Willis M, Schultz P, Milano K, Kliman H. Abnormal nuclear cyclin E expression in endometrial glands of patients with recurrent pregnancy loss (RPL): response to vaginal micronized progesterone adminstration. Fertility And Sterility 2009, 92: s244-s245. DOI: 10.1016/j.fertnstert.2009.07.1612.Peer-Reviewed Original Research
2001
Mouse ascites golgi (MAG) mucin expression and regulation by progesterone in the rat uterus.
Schwartz LB, Naftolin F, Lyttle CR, Penzias AS, Meaddough EL, Kliman HJ. Mouse ascites golgi (MAG) mucin expression and regulation by progesterone in the rat uterus. Reproductive Sciences 2001, 8: 216-23. PMID: 11525897, DOI: 10.1016/s1071-5576(01)00115-0.Peer-Reviewed Original ResearchConceptsPregnant mare serum gonadotropinSprague-Dawley ratsEndometrial glandsAdult Sprague-Dawley ratsImmature Sprague-Dawley ratsBlood group AGlandular stainingHormonal groupsEndometrial receptivitySerum gonadotropinMucin expressionSprague-DawleyUntreated groupGroup ARat uterusMaximal responseMAG expressionBlood analysisStimulatory effectRU486Glycoprotein epitopesRatsEpitopesGlandProgesteroneMouse Ascites Golgi (MAG) Mucin Expression and Regulation by Progesterone in the Rat Uterus
Schwartz L, Naftolin F, Lyttle C, Penzias A, Meaddough E, Kliman H. Mouse Ascites Golgi (MAG) Mucin Expression and Regulation by Progesterone in the Rat Uterus. Reproductive Sciences 2001, 8: 216-223. DOI: 10.1177/107155760100800406.Peer-Reviewed Original ResearchPregnant mare serum gonadotropinSprague-Dawley ratsEndometrial glandsAdult Sprague-Dawley ratsImmature Sprague-Dawley ratsBlood group AGlandular stainingHormonal groupsEndometrial receptivitySerum gonadotropinMucin expressionSprague-DawleyUntreated groupGroup ARat uterusMaximal responseMAG expressionBlood analysisStimulatory effectRU486Glycoprotein epitopesRatsEpitopesGlandProgesterone
1995
A mucin-like glycoprotein identified by MAG (mouse ascites Golgi) antibodies. Menstrual cycle-dependent localization in human endometrium.
Kliman HJ, Feinberg RF, Schwartz LB, Feinman MA, Lavi E, Meaddough EL. A mucin-like glycoprotein identified by MAG (mouse ascites Golgi) antibodies. Menstrual cycle-dependent localization in human endometrium. American Journal Of Pathology 1995, 146: 166-81. PMID: 7531946, PMCID: PMC1870765.Peer-Reviewed Original ResearchConceptsMAG antibodyMucin-like glycoproteinHigh molecular weight mucin-like glycoproteinBlood groupCycle days 5Bile duct epitheliumAnti-MAG antibodiesConceptus-endometrial interactionsExpression of mucinsBlood type ABlood group AHuman endometrial glandsEndometrial biopsyPancreatic acinar cellsEndometrial glandsEndometrial surfaceIgG antibodiesImplantation windowHuman endometriumImmunohistochemical stainingGroup AGall bladderLuminal epitheliumDuct epitheliumLacrimal gland