2012
Learning and Memory Depend on Fibroblast Growth Factor Receptor 2 Functioning in Hippocampus
Stevens HE, Jiang GY, Schwartz ML, Vaccarino FM. Learning and Memory Depend on Fibroblast Growth Factor Receptor 2 Functioning in Hippocampus. Biological Psychiatry 2012, 71: 1090-1098. PMID: 22541947, PMCID: PMC3371339, DOI: 10.1016/j.biopsych.2012.03.013.Peer-Reviewed Original ResearchConceptsFGF receptor 2Fibroblast growth factorDentate gyrusReceptor 2Embryonic knockoutWater maze probe trialGrowth factor receptor 2Reference memoryFactor receptor 2Spatial reference memoryNeural stem cellsFibroblast growth factor receptor 2Immature neuronsCortical neuronsHippocampal volumeInducible knockout miceParvalbumin interneuronsShort-term learningGranule cellsKnockout miceSeparate cellular componentsHippocampusLong-term reference memoryAdult spatial memoryGrowth factor
2010
Neural Stem Cell Regulation, Fibroblast Growth Factors, and the Developmental Origins of Neuropsychiatric Disorders
Stevens HE, Smith KM, Rash BG, Vaccarino FM. Neural Stem Cell Regulation, Fibroblast Growth Factors, and the Developmental Origins of Neuropsychiatric Disorders. Frontiers In Neuroscience 2010, 4: 59. PMID: 20877431, PMCID: PMC2944667, DOI: 10.3389/fnins.2010.00059.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsNeural stem cellsFibroblast growth factorGrowth factorPsychiatric disordersNeuropsychiatric disordersBrain-derived growth factorEmbryonic neural stem cellsNeural stem cell regulationStem cell regulationMajor depressionPsychiatric illnessAdult brainNeurodevelopmental underpinningsMental disordersNeuronal precursorsReceptor tyrosine kinasesCandidate susceptibility genesSchizophrenia 1DisordersHomeodomain genesMental retardationAbnormal specificationCell biologyDevelopmental originsMultipotent cells