Do psychotropic drugs cause seizures?
Gopaul M, Altalib H. Do psychotropic drugs cause seizures? Epilepsy & Behavior Reports 2024, 27: 100679. PMID: 38881884, PMCID: PMC11179069, DOI: 10.1016/j.ebr.2024.100679.Peer-Reviewed Original ResearchAttention-deficit/hyperactivity disorderPsychiatric comorbiditiesPsychotropic medicationsTricyclic antidepressantsCNS stimulantsSerotonin reuptake inhibitorsConcurrent psychiatric disordersSeizure riskReuptake inhibitorsAttention-deficit/hyperactivityPsychiatric disordersPsychiatric symptomsIncreased seizure riskPsychotropic drugsBidirectional associationsAnticonvulsant effectsAntidepressantsIatrogenic seizuresAntipsychoticsTreatment outcomesDisordersHigh dosesClinical decision-makingSeizure onsetEpilepsySuicide and Seizures
Bornovski Y, Jackson-Shaheed E, Argraves S, Hitchins A, Tolchin B, Galluzzo D, Cheung KH, Goulet J, Skanderson M, Brandt CA, Pugh MJ, Altalib H. Suicide and Seizures. Neurology Clinical Practice 2021, 11: 372-376. PMID: 34840864, PMCID: PMC8610527, DOI: 10.1212/cpj.0000000000001070.Peer-Reviewed Original ResearchPsychogenic nonepileptic seizuresSuicide-related behaviorsCohort studyRates of suicideRelative riskHigh riskVeterans Health Administration (VHA) servicesRetrospective cohort studyComparison groupNational cohort studyStandardized mortality ratioGeneral veteran populationIllicit drug abusePosttraumatic stress disorderElectronic health recordsDecreased riskPsychotropic medicationsMortality ratioMajor depressionNonepileptic seizuresAlcohol abuseVeteran populationEpilepsySeizuresPoisson regression