2011
Obesity is an independent risk factor for clinical decompensation in patients with cirrhosis
Berzigotti A, Garcia‐Tsao G, Bosch J, Grace ND, Burroughs AK, Morillas R, Escorsell A, Garcia‐Pagan J, Patch D, Matloff DS, Groszmann RJ, Group T. Obesity is an independent risk factor for clinical decompensation in patients with cirrhosis. Hepatology 2011, 54: 555-561. PMID: 21567436, PMCID: PMC3144991, DOI: 10.1002/hep.24418.Peer-Reviewed Original ResearchConceptsBody mass indexClinical decompensationPortal pressureBMI groupsNormal body mass indexRole of obesityChronic viral hepatitisIndependent risk factorSubset of patientsValuable therapeutic measureActuarial probabilityCompensated cirrhosisViral hepatitisAggressive courseIndependent predictorsMass indexRandomized trialsLiver functionPatient populationRisk factorsTherapeutic measuresStudy populationCirrhosisTreatment groupsPatients
1995
Cirrhotic ascites: pathogenesis and management.
Garcia-Tsao G. Cirrhotic ascites: pathogenesis and management. The Gastroenterologist 1995, 3: 41-54. PMID: 7743121.BooksConceptsPathogenesis of ascitesComplications of cirrhosisNegative sodium balanceAccumulation of fluidSinusoidal hypertensionLiver transplantationSalt restrictionPortosystemic shuntingPeripheral vasoconstrictorNonsurgical sideIntravascular volumeCurrent therapiesIntraperitoneal fluidSodium balanceTherapeutic priorityTherapeutic measuresPeritoneal spacePeritoneal cavitySystemic circulationAscitesEfflux of fluidPatientsDiureticsPathogenesisFuture studies