1991
Idiopathic portal hypertension.
Orozco H, Takahashi T, García-Tsao G, Mercado M, Diliz H, Hernández-Ortiz J. Idiopathic portal hypertension. Revista De Investigación Clínica 1991, 43: 80-6. PMID: 1866503.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsIdiopathic portal hypertensionPortal hypertensionHigh re-bleeding rateMain histopathologic findingsNoncirrhotic portal fibrosisObliterative portal venopathySmall portal veinsRe-bleeding rateIntra-abdominal infectionsLong-term prognosisUpper gastrointestinal tractHepatitis B virusEsophago-gastric varicesChronic sclerotherapyHepatoportal sclerosisIPH patientsPortal venopathyPharmacologic managementVariceal bleedingCirrhotic patientsImmunologic abnormalitiesPortal fibrosisLiver failurePeriportal fibrosisSuch patients
1988
Colchicine in the Treatment of Cirrhosis of the Liver
Kershenobich D, Vargas F, Garcia-Tsao G, Tamayo R, Gent M, Rojkind M. Colchicine in the Treatment of Cirrhosis of the Liver. New England Journal Of Medicine 1988, 318: 1709-1713. PMID: 3287167, DOI: 10.1056/nejm198806303182602.Peer-Reviewed Original ResearchConceptsTreatment of cirrhosisPlacebo groupHistologic improvementColchicine groupSurvival rateMinimal portal fibrosisPlacebo-controlled trialPercent of patientsUse of colchicineAlcoholic cirrhosisOverall survivalPortal fibrosisMore biopsiesHepatic cirrhosisLiver biopsyPosthepatitic cirrhosisHistologic studyC. FiftyCirrhosisSide effectsPatientsCollagen synthesisLiverBiopsyPreliminary evidence