1987
Effects of Cyclosporine on Chronic Cytomegalovirus Infection in the Guinea Pig
Markham D, Griffith B, Lerner E, Lucia H, Bia F. Effects of Cyclosporine on Chronic Cytomegalovirus Infection in the Guinea Pig. Intervirology 1987, 28: 171-180. PMID: 2836336, DOI: 10.1159/000150013.Peer-Reviewed Original ResearchConceptsCytomegalovirus infectionLymphoid tissueGuinea pig cytomegalovirus infectionDetectable systemic diseaseGPCMV-infected animalsChronic cytomegalovirus infectionEffect of cyclosporineCMV isolationImmunosuppressed groupSystemic diseaseGuinea pigsExperimental animalsCs immunosuppressionCyclosporineIsolation rateDrug vehicleInfectionTissueAnimalsImmunosuppressionGavageDisease
1985
Effects of Cyclosporine on the Pathogenesis of Primary Cytomegalovirus Infection in the Guinea Pig
Bia F, Lucia H, Bia M, Vine W, Tuttle A. Effects of Cyclosporine on the Pathogenesis of Primary Cytomegalovirus Infection in the Guinea Pig. Intervirology 1985, 24: 154-165. PMID: 2999030, DOI: 10.1159/000149635.Peer-Reviewed Original ResearchConceptsPrimary cytomegalovirus infectionGuinea pigsCytomegalovirus infectionPrimary CMV infectionEffect of cyclosporinePresence of CMVGuinea pig CMVGuinea pig modelInternal organsHartley guinea pigsTotal body weightUntreated controlsCMV isolationOral CsACMV infectionCsA administrationLymphocyte valuesLymphocytes/Inflammatory responseMean changeViral inclusionsBody weightPig modelDay 0CMV