2008
Relationship of pre-surgery metabolic and physiological MR imaging parameters to survival for patients with untreated GBM
Crawford FW, Khayal IS, McGue C, Saraswathy S, Pirzkall A, Cha S, Lamborn KR, Chang SM, Berger MS, Nelson SJ. Relationship of pre-surgery metabolic and physiological MR imaging parameters to survival for patients with untreated GBM. Journal Of Neuro-Oncology 2008, 91: 337. PMID: 19009235, PMCID: PMC3022444, DOI: 10.1007/s11060-008-9719-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAspartic AcidBrain MappingBrain NeoplasmsCholineCreatineDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingFemaleGlioblastomaHumansImage EnhancementImage Processing, Computer-AssistedKaplan-Meier EstimateLactic AcidLipidsMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMiddle AgedProtonsRadionuclide ImagingRetrospective StudiesConceptsGlioblastoma multiformeApparent diffusion coefficientPoor survivalConventional anatomical MR imagingAnatomical MR imagingUntreated glioblastoma multiformeT2 hyperintense lesionsMedian survival timeLow-risk groupBlood-brain barrierStratification of patientsContrast-enhancing lesionsPerfusion-weighted imagingDiffusion-weighted imagingPhysiological MRProton MR spectroscopicFavorable survivalSurgical resectionT2 lesionsHyperintense lesionsPrognostic valueBrain barrierElevated cholineClinical trialsLesion volume
2005
Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging.
Cha S, Tihan T, Crawford F, Fischbein NJ, Chang S, Bollen A, Nelson SJ, Prados M, Berger MS, Dillon WP. Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging. American Journal Of Neuroradiology 2005, 26: 266-73. PMID: 15709123, PMCID: PMC7974081.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBlood VolumeContrast MediaDiagnosis, DifferentialFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedOligodendrogliomaConceptsBlood volume measurementsDSC-MR imagingLow-grade oligodendrogliomasMR imagingWorld Health Organization grade II astrocytomaGrade II astrocytomasContrast-enhanced MR imagingCerebral blood volume measurementsLow-grade astrocytomasContrast-enhanced MRLow-grade gliomasSpecific tumor markersDynamic susceptibility contrast-enhanced MR imagingMaximum relative CBVDiagnosis of gliomaSurgical resectionConsecutive patientsHistologic confirmationHistologic subtypeCommon subtypeHistopathologic evaluationMorphologic aberrationsTumor vascularityTumor markersAnatomic imaging