2022
External validation of yonsei nomogram predicting chronic kidney disease development after partial nephrectomy: An international, multicenter study
Raheem A, Landi I, Alowidah I, Capitanio U, Montorsi F, Larcher A, Derweesh I, Ghali F, Mottrie A, Mazzone E, De Naeyer G, Campi R, Sessa F, Carini M, Minervini A, Raman J, Rjepaj C, Kriegmair M, Autorino R, Veccia A, Mir M, Claps F, Choi Y, Ham W, Santok G, Tadifa J, Syling J, Furlan M, Simeone C, Bada M, Celia A, Carrión D, Bazan A, Ruiz C, Malki M, Barber N, Hussain M, Micali S, Puliatti S, Ghaith A, Hagras A, Ghoneem A, Eissa A, Alqahtani A, Rumaih A, Alwahabi A, Alenzi M, Pavan N, Traunero F, Antonelli A, Porcaro A, Illiano E, Costantini E, Rha K. External validation of yonsei nomogram predicting chronic kidney disease development after partial nephrectomy: An international, multicenter study. International Journal Of Urology 2022, 30: 308-317. PMID: 36478459, DOI: 10.1111/iju.15108.Peer-Reviewed Original ResearchConceptsNew-onset CKDCKD stageChronic kidney disease developmentExternal validationCKD stage ICT1 renal massesKidney disease developmentPreoperative eGFRPatient ageConsecutive patientsMulticenter studyTumor sizePartial nephrectomyRenal massesProgression rateGood calibration propertiesStage IProgression probabilityPatientsNomogramIndividual riskCKDDisease developmentEGFRMedian value
2020
Utilization of renal mass biopsy in patients with localized renal cell carcinoma: A population-based study utilizing the National Cancer Database
Patel DN, Ghali F, Meagher MF, Javier-Desloges J, Patel SH, Soliman S, Hakimi K, Yuan J, Murphy J, Derweesh IH. Utilization of renal mass biopsy in patients with localized renal cell carcinoma: A population-based study utilizing the National Cancer Database. Urologic Oncology Seminars And Original Investigations 2020, 39: 79.e1-79.e8. PMID: 33160847, DOI: 10.1016/j.urolonc.2020.10.015.Peer-Reviewed Original ResearchConceptsUse of RMBRenal mass biopsyRenal cell carcinomaNational Cancer DatabaseCell carcinomaMultivariable analysisCancer DatabaseMass biopsyCharlson Comorbidity IndexCurrent guideline recommendationsYear of diagnosisPopulation-based studySmall renal massesComorbidity indexSurgical treatmentGuideline recommendationsTumor sizeRenal massesPersistent underutilizationPatientsCarcinomaStudy periodTumorsBiopsyHigh rateComparison of renal functional outcomes of active surveillance and partial nephrectomy in the management of oncocytoma
Meagher M, Lane B, Capitanio U, Mehrazin R, Bradshaw A, Noyes S, Larcher A, Eldefrawy A, Ghali F, Patel D, Bruinius J, Dutt R, Keiner C, Miller N, Wan F, Montorsi F, Derweesh I. Comparison of renal functional outcomes of active surveillance and partial nephrectomy in the management of oncocytoma. World Journal Of Urology 2020, 39: 1195-1201. PMID: 32556559, DOI: 10.1007/s00345-020-03299-5.Peer-Reviewed Original ResearchConceptsDe novo chronic kidney diseaseChronic kidney diseaseKaplan-Meier analysisPartial nephrectomyActive surveillanceMultivariable analysisBaseline eGFRTumor sizeFunctional outcomeFunctional declineCKD-free survivalGreater functional declineHigher RENAL scoreLower baseline eGFRRenal functional preservationRegression multivariable analysisClinical tumor sizeRenal functional outcomesTumor diameterKidney diseaseRENAL scoreFunctional preservationMedian changeRetrospective analysisSelect circumstancesImpact of diabetes mellitus on functional and survival outcomes in renal cell carcinoma: An international multicenter study.
Dutt R, Meagher M, Patil D, Saito K, Patel D, Ghali F, Keiner C, Miller N, Bradshaw A, Wan F, Yasuda Y, Fujii Y, Master V, Derweesh I. Impact of diabetes mellitus on functional and survival outcomes in renal cell carcinoma: An international multicenter study. Journal Of Clinical Oncology 2020, 38: 666-666. DOI: 10.1200/jco.2020.38.6_suppl.666.Peer-Reviewed Original ResearchRenal cell carcinomaIndependent risk factorChronic kidney diseaseKaplan-Meier analysisRadical nephrectomyMultivariable analysisPartial nephrectomyRisk factorsPresence of DMFunctional declineDM statusOverall survivalKidney functionRCC patientsTumor sizeCell carcinomaRenal functional declineAfrican American raceInternational multicenter studyEffects of DMNDM patientsRN patientsCause mortalityWorse OSDiabetes mellitusAssociation of robotic partial nephrectomy for clinical T2a renal mass with improved trifecta outcome compared to open partial nephrectomy: A single surgeon comparative analysis.
Ghali F, Elbakry A, Hamilton Z, Nasseri R, Eldefrawy A, Ryan S, Yim K, Patel S, Bradshaw A, Meagher M, Reddy M, Lee H, Derweesh I. Association of robotic partial nephrectomy for clinical T2a renal mass with improved trifecta outcome compared to open partial nephrectomy: A single surgeon comparative analysis. Journal Of Clinical Oncology 2020, 38: 653-653. DOI: 10.1200/jco.2020.38.6_suppl.653.Peer-Reviewed Original ResearchRobotic partial nephrectomyOpen PNPartial nephrectomyMultivariable analysisRENAL scoreRenal massesLower blood lossFirst-line optionMedian RENAL scoreAchievement of trifectaEGFR recoveryHospital staySelect patientsBlood lossConsecutive patientsMajor complicationsPositive marginsTumor sizeFunctional outcomeTrifecta achievementTrifecta outcomesRetrospective analysisMAIN OUTCOMESurgical qualityTrifecta ratesAssociation of De Ritis Ratio and Neutrophil Lymphocyte Ratio with renal functional decline and all-cause mortality in renal cell carcinoma.
Keiner C, Meagher M, Patil D, Saito K, Patel D, Ghali F, Dutt R, Miller N, Bradshaw A, Wan F, Yasuda Y, Fuji Y, Master V, Derweesh I. Association of De Ritis Ratio and Neutrophil Lymphocyte Ratio with renal functional decline and all-cause mortality in renal cell carcinoma. Journal Of Clinical Oncology 2020, 38: 741-741. DOI: 10.1200/jco.2020.38.6_suppl.741.Peer-Reviewed Original ResearchNeutrophil-lymphocyte ratioPlatelet-lymphocyte ratioDe Ritis ratioKaplan-Meier analysisIndependent risk factorMultivariable analysisRenal cell carcinomaRisk factorsCause mortalityCell carcinomaFunctional declinePre-operative neutrophil-lymphocyte ratioElevated neutrophil-lymphocyte ratioMulti-institutional retrospective analysisDe novo CKDRenal functional declineHigh-risk patientsGlomerular filtration rateDe novoWorse OSLymphocyte ratioMale sexTumor sizeBlack raceFiltration rateUtilization of renal mass biopsy in patients with localized renal cell carcinoma: A population-based study utilizing the National Cancer Database.
Patel D, Ghali F, Patel S, Miller N, Bradshaw A, Meagher M, Rivera-Sanfeliz G, Murphy J, Derweesh I. Utilization of renal mass biopsy in patients with localized renal cell carcinoma: A population-based study utilizing the National Cancer Database. Journal Of Clinical Oncology 2020, 38: 662-662. DOI: 10.1200/jco.2020.38.6_suppl.662.Peer-Reviewed Original ResearchUse of RMBRenal cell carcinomaRenal mass biopsyNational Cancer DatabaseMultivariable logistic regressionTumor sizeCell carcinomaActive surveillanceCancer DatabaseMass biopsyLogistic regressionStudy periodCharlson Comorbidity IndexYear of diagnosisPopulation-based studyType of treatmentComorbidity indexSicker patientsBlack raceTumors 2Recent guidelinesTreatment strategiesPatientsAblation treatmentTumorsDoes delay in time to surgery impact outcome in renal cell carcinoma: Analysis based on tumor size utilizing the National Cancer Database.
Patel D, Ghali F, Meagher M, Bradshaw A, Patel S, Murphy J, Derweesh I. Does delay in time to surgery impact outcome in renal cell carcinoma: Analysis based on tumor size utilizing the National Cancer Database. Journal Of Clinical Oncology 2020, 38: 664-664. DOI: 10.1200/jco.2020.38.6_suppl.664.Peer-Reviewed Original ResearchMultivariable Cox proportional hazardsNational Cancer DatabaseRenal cell carcinomaKaplan-Meier analysisYears of ageTumor sizeSurgery delayWorse OSOverall survivalHealthy patientsCell carcinomaCancer DatabaseLocalized Renal Cell CarcinomaNon-private insuranceTumor size 2Charlson comorbidity scoreCox proportional hazardsComorbidity scoreSurgical treatmentSurvival impactMedian timeEntire cohortFourth quartileBlack raceActive surveillance
2019
Robotic partial nephrectomy for clinical T2a renal mass is associated with improved trifecta outcome compared to open partial nephrectomy: a single surgeon comparative analysis
Ghali F, Elbakry A, Hamilton Z, Yim K, Nasseri R, Patel S, Eldefrawy A, Ryan S, Bradshaw A, Meagher M, Bree K, Reddy M, Lee H, Derweesh I. Robotic partial nephrectomy for clinical T2a renal mass is associated with improved trifecta outcome compared to open partial nephrectomy: a single surgeon comparative analysis. World Journal Of Urology 2019, 38: 1113-1122. PMID: 31701211, DOI: 10.1007/s00345-019-02994-2.Peer-Reviewed Original ResearchConceptsPartial nephrectomyOpen PNRenal massesMultivariable analysisRENAL scoreResultsMean tumor sizeLower blood lossBurden of morbidityFirst-line optionT2 renal massesOpen partial nephrectomyRobotic partial nephrectomyMedian RENAL scoreAchievement of trifectaEGFR recoveryHospital staySelect patientsBlood lossConsecutive patientsMajor complicationsMethodsRetrospective analysisPositive marginsTumor sizeFunctional outcomeTrifecta achievement
2016
What factors are associated with unplanned return following transurethral resection of bladder tumor? An analysis of a large single institution’s experience
Ghali F, Moses R, Raffin E, Hyams E. What factors are associated with unplanned return following transurethral resection of bladder tumor? An analysis of a large single institution’s experience. Scandinavian Journal Of Urology 2016, 50: 370-373. PMID: 27438524, DOI: 10.1080/21681805.2016.1201856.Peer-Reviewed Original ResearchConceptsAspirin therapyPreoperative antibioticsGross hematuriaMultivariable analysisTransurethral resectionTumor sizeBladder tumorsOperating roomFemale genderLargest single-institution experienceSingle institution experienceDay of surgeryFoley catheter placementLength of staySingle academic institutionHospital dischargeRetrospective reviewUnplanned returnCatheter placementFoley catheterizationInstitution experienceMean ageFoley placementDistance of residenceCommon cause