The impact of metastasis location on overall survival among patients with renal cell carcinoma.
Patel D, Ghali F, Meagher M, Meagher M, Bradshaw A, Patel S, Keiner C, Miller N, Dutt R, Murphy J, Derweesh I. The impact of metastasis location on overall survival among patients with renal cell carcinoma. Journal Of Clinical Oncology 2020, 38: 621-621. DOI: 10.1200/jco.2020.38.6_suppl.621.Peer-Reviewed Original ResearchMetastatic renal cell carcinomaRenal cell carcinomaNational Cancer DatabaseLiver/lung metastasisOverall survivalBone metastasesLung metastasesCell carcinomaInstitutional databaseUnivariate analysisMetastasis locationWorse OSSite metastasisDisease locationMultivariable Cox proportional hazardsKaplan-Meier survival analysisCurrent staging guidelinesLung/liver metastasisLog-rank testingWorse overall survivalHeterogeneity of patientsCox proportional hazardsLung/liverLiver metastasesMetastatic diseaseDoes delay in time to surgery impact outcome in renal cell carcinoma: Analysis based on tumor size utilizing the National Cancer Database.
Patel D, Ghali F, Meagher M, Bradshaw A, Patel S, Murphy J, Derweesh I. Does delay in time to surgery impact outcome in renal cell carcinoma: Analysis based on tumor size utilizing the National Cancer Database. Journal Of Clinical Oncology 2020, 38: 664-664. DOI: 10.1200/jco.2020.38.6_suppl.664.Peer-Reviewed Original ResearchMultivariable Cox proportional hazardsNational Cancer DatabaseRenal cell carcinomaKaplan-Meier analysisYears of ageTumor sizeSurgery delayWorse OSOverall survivalHealthy patientsCell carcinomaCancer DatabaseLocalized Renal Cell CarcinomaNon-private insuranceTumor size 2Charlson comorbidity scoreCox proportional hazardsComorbidity scoreSurgical treatmentSurvival impactMedian timeEntire cohortFourth quartileBlack raceActive surveillanceDoes pathologic upstaging to PT3A portend a worsened prognosis when compared to non-upstaged PT3A renal cell carcinoma: Analysis of the National Cancer Database.
Patel D, Ghali F, Meagher M, Bradshaw A, Patel S, Keiner C, Miller N, Dutt R, Murphy J, Derweesh I. Does pathologic upstaging to PT3A portend a worsened prognosis when compared to non-upstaged PT3A renal cell carcinoma: Analysis of the National Cancer Database. Journal Of Clinical Oncology 2020, 38: 624-624. DOI: 10.1200/jco.2020.38.6_suppl.624.Peer-Reviewed Original ResearchPT3a renal cell carcinomaRenal cell carcinomaNational Cancer DatabasePartial nephrectomyClinical stageOverall survivalPT3a tumorsCell carcinomaPathological upstagingUpstaged tumorsCancer DatabaseT3a renal cell carcinomaMultivariable Cox proportional hazardsKaplan-Meier survival analysisPre-treatment detectionRisk stratification protocolCharlson Comorbidity IndexImproved overall survivalFinal pathological analysisAJCC staging systemKaplan-Meier analysisSmaller tumor sizeLower clinical stagePositive margin statusCox proportional hazards