2024
Social skills in patients with obsessive-compulsive disorder before and after treatment.
da Silva F, Batistuzzo M, Diniz J, D'Alcante C, Timpano K, Shavitt R, Miguel E, Hoexter M. Social skills in patients with obsessive-compulsive disorder before and after treatment. Brazilian Journal Of Psychiatry 2024 PMID: 38875529, DOI: 10.47626/1516-4446-2024-3577.Peer-Reviewed Original ResearchObsessive-compulsive disorderObsessive-compulsive disorder symptomatologySocial skillsIllness durationControl participantsSeverity of obsessive-compulsive disorderObsessive-compulsive disorder severityObsessive-compulsive disorder symptomsSS total scoreScores compared to controlsOCD symptomatologyGroup differencesIllness onsetPredictors of SSTotal scoreCourse of treatmentSymptomatologyTreatment investigationsSS performanceTreatment effectsIllnessDisordersTreatment-naive patientsSkillsFollow-up period
2011
Gray Matter Volumes in Obsessive-Compulsive Disorder Before and After Fluoxetine or Cognitive-Behavior Therapy: A Randomized Clinical Trial
Hoexter M, de Souza Duran F, D'Alcante C, Dougherty D, Shavitt R, Lopes A, Diniz J, Deckersbach T, Batistuzzo M, Bressan R, Miguel E, Busatto G. Gray Matter Volumes in Obsessive-Compulsive Disorder Before and After Fluoxetine or Cognitive-Behavior Therapy: A Randomized Clinical Trial. Neuropsychopharmacology 2011, 37: 734-745. PMID: 22030709, PMCID: PMC3260985, DOI: 10.1038/npp.2011.250.Peer-Reviewed Original ResearchConceptsCognitive behavior therapyObsessive-compulsive disorderGray matter volumeLeft putamenClinical trialsOCD patientsGM volumeMatter volumeSignificant GM volume changesPathophysiology of OCDFluoxetine-treated patientsGM volume abnormalitiesMatched-healthy controlsTreatment-naive patientsFirst-line treatmentStructural brain abnormalitiesGM volume changesCBT-treated patientsGroup cognitive behavior therapySmaller GM volumeRegional brain volumesRegional brain morphologyAnterior cingulate cortexStructural magnetic resonanceRegional gray matter volume