2019
The impact of attention deficit hyperactivity disorder in obsessive‐compulsive disorder subjects
Blanco‐Vieira T, Santos M, Ferrão YA, Torres AR, Miguel EC, Bloch MH, Leckman JF, do Rosario MC. The impact of attention deficit hyperactivity disorder in obsessive‐compulsive disorder subjects. Depression And Anxiety 2019, 36: 533-542. PMID: 30990937, DOI: 10.1002/da.22898.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderAdult OCD patientsObsessive-compulsive disorderDeficit hyperactivity disorderOCD patientsClinical characteristicsExact testFeatures of ADHDHyperactivity disorderSubgroup of patientsAdult obsessive-compulsive disorderComorbid attention deficit hyperactivity disorderSpecific clinical featuresCross-sectional studyObsessive-compulsive disorder (OCD) subjectsLogistic regression analysisFisher's exact testBrazilian Research ConsortiumMann-Whitney testAdult patientsRheumatic feverDevelopment of interventionsClinical featuresObsessive-compulsive spectrum disordersLifetime prevalence
2016
Use of benzodiazepines in obsessive–compulsive disorder
Starcevic V, Berle D, do Rosário M, Brakoulias V, Ferrão Y, Viswasam K, Shavitt R, Miguel E, Fontenelle L. Use of benzodiazepines in obsessive–compulsive disorder. International Clinical Psychopharmacology 2016, 31: 27-33. PMID: 26426443, DOI: 10.1097/yic.0000000000000100.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-Anxiety AgentsAnxietyBenzodiazepinesCross-Sectional StudiesDiagnostic and Statistical Manual of Mental DisordersDrug Therapy, CombinationFemaleHumansMaleMiddle AgedObsessive-Compulsive DisorderPsychiatric Status Rating ScalesSelective Serotonin Reuptake InhibitorsSocioeconomic FactorsConceptsObsessive-compulsive disorderBDZ useOCD patientsUse of benzodiazepinesTreatment of OCDBrazilian Research ConsortiumAdditional medicationTreatment guidelinesMulticentre studyReuptake inhibitorsObsessive-compulsive spectrum disordersBenzodiazepine useMarked anxietyPatientsMedicationsBDZDisordersResearch ConsortiumCurrent age
2014
Phenomenology of OCD: Lessons from a large multicenter study and implications for ICD-11
Shavitt R, de Mathis M, Oki F, Ferrao Y, Fontenelle L, Torres A, Diniz J, Costa D, do Rosário M, Hoexter M, Miguel E, Simpson H. Phenomenology of OCD: Lessons from a large multicenter study and implications for ICD-11. Journal Of Psychiatric Research 2014, 57: 141-148. PMID: 25012187, PMCID: PMC7326117, DOI: 10.1016/j.jpsychires.2014.06.010.Peer-Reviewed Original Research
2013
Panic Disorder and Agoraphobia in OCD patients: Clinical profile and possible treatment implications
Torres A, Ferrão Y, Shavitt R, Diniz J, Costa D, do Rosário M, Miguel E, Fontenelle L. Panic Disorder and Agoraphobia in OCD patients: Clinical profile and possible treatment implications. Comprehensive Psychiatry 2013, 55: 588-597. PMID: 24374170, DOI: 10.1016/j.comppsych.2013.11.017.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderPanic disorderClinical profileOCD patientsMajor depressionPrevalence of PDDSM-IV-TR Axis I DisordersCross-sectional studyAxis I DisordersStructured Clinical InterviewPD/agoraphobiaBrazilian Research ConsortiumLogistic regression modelsPosttraumatic stress disorderLarge clinical sampleYale-Brown ObsessiveComorbid conditionsPD comorbidityIndependent correlatesObsessive-compulsive spectrum disordersLifetime prevalenceTreatment strategiesI disordersStudy groupSeparation anxiety disorderLate-onset obsessive-compulsive disorder: Risk factors and correlates
Frydman I, do Brasil PE, Torres AR, Shavitt RG, Ferrão YA, Rosário MC, Miguel EC, Fontenelle LF. Late-onset obsessive-compulsive disorder: Risk factors and correlates. Journal Of Psychiatric Research 2013, 49: 68-74. PMID: 24267559, DOI: 10.1016/j.jpsychires.2013.10.021.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderLate-onset obsessive-compulsive disorderSubclinical obsessive-compulsive symptomsPosttraumatic stress disorderObsessive-compulsive symptomsOnset obsessive-compulsive disorderObsessive-compulsive spectrum disordersMajor traumatic eventEarly-onset obsessive-compulsive disorderBrazilian Research ConsortiumTraumatic eventsSpectrum disorderStress disorderOCD symptomsOCD onsetDearth of studiesSelfCorrelatesDisordersPotential variablesNeural networkDistressSymptomsSizeable proportionSeries of modelsClinical features of pure obsessive-compulsive disorder
Torres A, Shavitt R, Torresan R, Ferrão Y, Miguel E, Fontenelle L. Clinical features of pure obsessive-compulsive disorder. Comprehensive Psychiatry 2013, 54: 1042-1052. PMID: 23746710, DOI: 10.1016/j.comppsych.2013.04.013.Peer-Reviewed Original ResearchConceptsPure obsessive-compulsive disorderNon-comorbid patientsObsessive-compulsive disorderYale-Brown ObsessiveClinical characteristicsDSM-IV Axis I DisordersSuicidal thoughtsLogistic regressionCompulsive ScaleOCD patientsAnxious symptomsAxis I comorbidityCross-sectional studyAxis I DisordersStructured Clinical InterviewCo-occurring disordersPrevious suicidal thoughtsBrazilian Research ConsortiumLarge multicenter samplePure OCD patientsAdult patientsClinical featuresLifetime comorbidityPsychiatric comorbidityObsessive-compulsive spectrum disordersSymptom dimensions, clinical course and comorbidity in men and women with obsessive-compulsive disorder
Torresan R, Ramos-Cerqueira A, Shavitt R, do Rosário M, de Mathis M, Miguel E, Torres A. Symptom dimensions, clinical course and comorbidity in men and women with obsessive-compulsive disorder. Psychiatry Research 2013, 209: 186-195. PMID: 23298952, DOI: 10.1016/j.psychres.2012.12.006.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderClinical courseComorbid post-traumatic stress disorderDSM-IV Axis ICross-sectional studyStructured Clinical InterviewAlcohol use disorderSymptom dimensionsPost-traumatic stress disorderAdult OCD patientsBrazilian Research ConsortiumYale-Brown ObsessiveFemale patientsClinical presentationMean ageSymptom interferenceObsessive-compulsive spectrum disordersMajor depressionTic disordersFemale genderAxis IUse disordersClinical InterviewAnorexia nervosaSkin picking
2012
Social phobia in obsessive-compulsive disorder: Prevalence and correlates
Assunção M, da Conceição Costa D, de Mathis M, Shavitt R, Ferrão Y, do Rosário M, Miguel E, Torres A. Social phobia in obsessive-compulsive disorder: Prevalence and correlates. Journal Of Affective Disorders 2012, 143: 138-147. PMID: 22858214, DOI: 10.1016/j.jad.2012.05.044.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceAnxiety DisordersBody Dysmorphic DisordersBrazilComorbidityCross-Sectional StudiesDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMaleMiddle AgedObsessive-Compulsive DisorderPhobic DisordersPrevalenceRetrospective StudiesSex FactorsSocial ClassTourette SyndromeConceptsObsessive-compulsive disorderDSM-IV Axis I DisordersLogistic regressionSocial phobiaAnxiety disordersOCD patientsCross-sectional studyStructured Clinical InterviewAxis I DisordersLow socioeconomic statusBrazilian Research ConsortiumLarge multicenter sampleBroader treatment approachesGeneralized anxiety disorderBody dysmorphic disorderYale-Brown ObsessiveClinical factorsCross-sectional designSpecific comorbiditiesMale sexObsessive-compulsive spectrum disordersUnivariate analysisLifetime prevalenceI disordersTourette syndromeBODY DYSMORPHIC DISORDER IN PATIENTS WITH OBSESSIVE–COMPULSIVE DISORDER: PREVALENCE AND CLINICAL CORRELATES
Costa D, Assunção M, Ferrão Y, Conrado L, Gonzalez C, Fontenelle L, Fossaluza V, Miguel E, Torres A, Shavitt R. BODY DYSMORPHIC DISORDER IN PATIENTS WITH OBSESSIVE–COMPULSIVE DISORDER: PREVALENCE AND CLINICAL CORRELATES. Depression And Anxiety 2012, 29: 966-975. PMID: 22815241, DOI: 10.1002/da.21980.Peer-Reviewed Original ResearchConceptsBody dysmorphic disorderObsessive-compulsive disorderSkin pickingYale-Brown ObsessiveDSM-IV Axis I DisordersClinical Global Impression ScaleEarly onsetCompulsive ScaleOCD patientsDysmorphic disorderGroup of patientsSymptoms of BDDGlobal Impression ScaleAxis I DisordersStructured Clinical InterviewComorbid body dysmorphic disorderBrazilian Research ConsortiumYounger patientsUnemployed patientsClinical featuresObsessive-compulsive spectrum disordersClinical correlatesImpression ScaleChronic depressionClinical assessmentClinical correlates of social adjustment in patients with obsessive-compulsive disorder
Rosa A, Diniz J, Fossaluza V, Torres A, Fontenelle L, De Mathis A, da Conceição Rosário M, Miguel E, Shavitt R. Clinical correlates of social adjustment in patients with obsessive-compulsive disorder. Journal Of Psychiatric Research 2012, 46: 1286-1292. PMID: 22800713, DOI: 10.1016/j.jpsychires.2012.05.019.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderPoor social adjustmentSocial adjustmentSocial functioningOverall social functioningYale-Brown ObsessiveOCD severityReligious obsessionsCompulsive ScaleCurrent post-traumatic stress disorderSpecific OCD symptomsPost-traumatic stress disorderPrimary DSM-IV diagnosisOCD symptom onsetPoor social functioningSocial adjustment measuresObsessive-compulsive spectrum disordersGreater OCD severitySocial Adjustment ScaleBrazilian Research ConsortiumPoorer overall social functioningDimensional Yale-Brown ObsessivePsychiatric comorbidityCurrent psychiatric comorbidityCurrent major depressive disorderClinical features of obsessive-compulsive disorder with hoarding symptoms: A multicenter study
Torres A, Fontenelle L, Ferrão Y, do Rosário M, Torresan R, Miguel E, Shavitt R. Clinical features of obsessive-compulsive disorder with hoarding symptoms: A multicenter study. Journal Of Psychiatric Research 2012, 46: 724-732. PMID: 22464941, DOI: 10.1016/j.jpsychires.2012.03.005.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderClinical featuresOCD patientsLogistic regressionDSM-IV OCD patientsCertain clinical featuresCross-sectional studyAttention-deficit/hyperactivity disorderStatistical univariate analysisBrazilian Research ConsortiumDeficit/hyperactivity disorderHigher anxiety scoresYale-Brown ObsessiveSymptom onsetInsidious onsetMulticenter studyObsessive-compulsive spectrum disordersSectional studyPossible confoundersUnivariate analysisTic disordersHoarding dimensionPatientsSymptomsPoor insight
2009
Higher prevalence of obsessive–compulsive spectrum disorders in rheumatic fever
de Alvarenga P, Floresi A, Torres A, Hounie A, Fossaluza V, Gentil A, Pereira C, Miguel E. Higher prevalence of obsessive–compulsive spectrum disorders in rheumatic fever. General Hospital Psychiatry 2009, 31: 178-180. PMID: 19269540, DOI: 10.1016/j.genhosppsych.2008.11.003.Peer-Reviewed Original ResearchConceptsRheumatic feverObsessive-compulsive spectrum disordersHigh prevalencePrevious historyPsychiatric outpatientsAnalytical cross-sectional studyConsecutive psychiatric outpatientsCross-sectional studySubclinical obsessive-compulsive disorderObsessive-compulsive disorderPositive historySpectrum disorderPsychiatric diagnosisMental disordersRelated disordersSenior psychiatristsObsessive-compulsive symptomsStatistical ManualDisordersPrevalencePrivate practiceFeverOutpatientsFourth EditionSuch history
2008
Anxiety Disorders and Rheumatic Fever: Is There an Association?
Seixas A, Hounie A, Fossaluza V, Curi M, Alvarenga P, De Mathis M, De Mathis M, Vallada H, Pauls D, de Bragança Pereira C, Miguel E. Anxiety Disorders and Rheumatic Fever: Is There an Association? CNS Spectrums 2008, 13: 1039-1046. PMID: 19179939, DOI: 10.1017/s1092852900017090.Peer-Reviewed Original ResearchConceptsFirst-degree relativesRheumatic feverObsessive-compulsive spectrum disordersObsessive-compulsive disorderAnxiety disordersFamily membersCase-control family studyRates of disorderRelatives of individualsPoisson regression modelsRF patientsSydenham's choreaSeparation anxiety disorderPsychiatric interviewPossible familial relationshipControl probandsRelated disordersDisordersFamilial aggregationFurther studiesPatientsChoreaFeverOCD spectrumFamily studies
2006
Obsessive-Compulsive Spectrum Disorders and Rheumatic Fever: A Family Study
Hounie A, Pauls D, do Rosario-Campos M, Mercadante M, Diniz J, De Mathis M, De Mathis M, Chacon P, Shavitt R, Curi M, Guilherme L, Miguel E. Obsessive-Compulsive Spectrum Disorders and Rheumatic Fever: A Family Study. Biological Psychiatry 2006, 61: 266-272. PMID: 16616727, DOI: 10.1016/j.biopsych.2006.02.021.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBacterial ProteinsCase-Control StudiesChildData Interpretation, StatisticalFamilyFemaleHumansInterview, PsychologicalLogistic ModelsMaleObserver VariationObsessive-Compulsive DisorderOdds RatioPsychiatric Status Rating ScalesRheumatic FeverRiskStreptococcal InfectionsStreptolysinsConceptsFirst-degree relativesRheumatic feverObsessive-compulsive spectrum disordersSydenham's choreaFDRs of controlsStructured psychiatric interviewUnderlying etiologic mechanismsCase-control family studyFamily studiesControl first-degree relativesBest-estimate diagnosesHigh rateRF patientsCompulsive spectrum disordersOdds ratioMorbid riskEtiologic mechanismsPsychiatric interviewSpectrum disorderLogistic regressionProbandsFeverPatientsChoreaDiagnosis
2005
Obsessive-Compulsive Spectrum Disorders in Rheumatic Fever Patients
Mercadante M, Diniz J, Hounie A, Ferro Y, Alvarenga P, Brotto S, Miguel E. Obsessive-Compulsive Spectrum Disorders in Rheumatic Fever Patients. Journal Of Neuropsychiatry 2005, 17: 544-547. PMID: 16387996, DOI: 10.1176/jnp.17.4.544.Peer-Reviewed Original ResearchConceptsRheumatic fever patientsFever patientsObsessive-compulsive spectrum disordersCNS interactionsAutoimmune reactionsSpectrum disorderPsychiatric disordersDisordersPatients