2022
Shape analysis of subcortical structures in obsessive‐compulsive disorder and the relationship with comorbid anxiety, depression, and medication use: A meta‐analysis by the OCD Brain Imaging Consortium
Fouche J, Groenewold N, Sevenoaks T, Heany S, Lochner C, Alonso P, Batistuzzo M, Cardoner N, Ching C, de Wit S, Gutman B, Hoexter M, Jahanshad N, Kim M, Kwon J, Mataix‐Cols D, Menchon J, Miguel E, Nakamae T, Phillips M, Pujol J, Sakai Y, Yun J, Soriano‐Mas C, Thompson P, Yamada K, Veltman D, van den Heuvel O, Stein D. Shape analysis of subcortical structures in obsessive‐compulsive disorder and the relationship with comorbid anxiety, depression, and medication use: A meta‐analysis by the OCD Brain Imaging Consortium. Brain And Behavior 2022, 12: e2755. PMID: 36106505, PMCID: PMC9575597, DOI: 10.1002/brb3.2755.Peer-Reviewed Original ResearchConceptsCaudate nucleusHealthy controlsOCD patientsComorbid depressionMedication statusComorbid anxietySubcortical shapeSignificant differencesDeep gray matter structuresRight caudate nucleusCo-morbid anxietyLeft caudate nucleusObsessive-compulsive disorder patientsSubcortical brain morphologyGray matter structuresDisease durationMedication useObsessive-compulsive disorderSubgroup analysisBrain MRINucleus accumbensDisorder patientsPatientsBrain volumePutamen
2019
SU72 TRANSCRIPTOME STUDY IN OBSESSIVE COMPULSIVE DISORDERS
Lisboa B, Tahira A, Sant'Anna A, Oliveira K, Miguel E, Hoexter M, Farfel J, Brentani H. SU72 TRANSCRIPTOME STUDY IN OBSESSIVE COMPULSIVE DISORDERS. European Neuropsychopharmacology 2019, 29: s927. DOI: 10.1016/j.euroneuro.2017.08.261.Peer-Reviewed Original ResearchObsessive-compulsive disorderNucleus accumbensSubgenual cingulate gyrusCortico-striatal circuitryOrbitofrontal cortexAffective circuitryCingulate gyrusCaudate nucleusBrain areasCognitive circuitryBrazilian Aging Brain Study GroupCompulsive disorderEnsheathment of neuronsEnrichment analysisBackground Obsessive-compulsive disorderDrug metabolic processFunctional neuroimaging studiesCortico-striatal loopsDopaminergic synapsesBrain BankThalamic circuitryGene expressionStudy groupNeurological system processPsychiatric disorders