2020
Testing the Stability and Validity of an Executive Dysfunction Classification Using Task-Based Assessment in Children and Adolescents
Manfro A, Pine D, Polanczyk G, Santoro M, Smoller J, Koenen K, Mari J, Pan P, Zugman A, Schäfer J, Belangero S, Gosmann N, Simioni A, Hoexter M, Miguel E, Gadelha A, Rohde L, Salum G. Testing the Stability and Validity of an Executive Dysfunction Classification Using Task-Based Assessment in Children and Adolescents. Journal Of The American Academy Of Child & Adolescent Psychiatry 2020, 60: 1501-1512. PMID: 33346031, PMCID: PMC10259767, DOI: 10.1016/j.jaac.2020.11.016.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresPsychiatric diagnosisExecutive functionHigher schizophrenia polygenic risk scoresExecutive dysfunctionHigh Risk Cohort StudySmaller intracranial volumeHigher attention-deficit/hyperactivity disorderAttention-deficit/hyperactivity disorderSchizophrenia polygenic risk scoresCortical surface areaDichotomized ageCohort studyFunctional impairmentRisk scoreDomains of psychopathologyBrain regionsIntracranial volumeRelevant outcomesBrain structuresHyperactivity disorderCognitive tasksLatent class analysisLower chanceDiagnosis
2016
Children with Poor Reading Skills at the Word Level Show Reduced Fractional Anisotropy in White Matter Tracts of Both Hemispheres
de Moura L, Cogo-Moreira H, de Ávila C, Pan P, Gadelha A, Moriyama T, Del Aquilla M, Hoexter M, Salum G, Picon F, Anés M, Mercadante M, Lacerda A, Amaro E, Miguel E, Rohde L, Bressan R, McGuire P, Sato J, de Jesus Mari J, Jackowski A. Children with Poor Reading Skills at the Word Level Show Reduced Fractional Anisotropy in White Matter Tracts of Both Hemispheres. Brain Connectivity 2016, 6: 519-523. PMID: 27353747, DOI: 10.1089/brain.2016.0430.Peer-Reviewed Original ResearchConceptsWhite matter tractsRadial diffusivityDiffusion tensor imaging studyLatent class analysisSignificant fractional anisotropy reductionYears of ageReduced fractional anisotropyFractional anisotropy reductionsMultiple cortical regionsWhite matter microstructureWhite matterWidespread structural alterationsCortical regionsImaging studiesFractional anisotropyLeft hemisphereTract