2022
Neurocircuit models of obsessive-compulsive disorder: limitations and future directions for research
Shephard E, Batistuzzo M, Hoexter M, Stern E, Zuccolo P, Ogawa C, Silva R, Brunoni A, Costa D, Doretto V, Saraiva L, Cappi C, Shavitt R, Simpson H, van den Heuvel O, Miguel E. Neurocircuit models of obsessive-compulsive disorder: limitations and future directions for research. Brazilian Journal Of Psychiatry 2022, 44: 187-200. PMID: 35617698, PMCID: PMC9041967, DOI: 10.1590/1516-4446-2020-1709.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderCourse of OCDCognitive mechanismsCommon psychiatric conditionsSpecific neurocircuitsCognitive functionNeurocognitive functionPsychiatric conditionsFuture researchComplexity of brainFuture directionsDisordersCurrent reviewNeuroscienceNeurocircuitsCompulsionResearchSymptomatologyObsessionExperiences of patientsExperienceImportant limitationsPresentationBetter understandingBrain
2018
Childhood trauma and adolescent psychotic experiences in a community-based cohort: The potential role of positive attributes as a protective factor
Pan P, Gadelha A, Argolo F, Hoffmann M, Arcadepani F, Miguel E, Rohde L, McGuire P, Salum G, Bressan R. Childhood trauma and adolescent psychotic experiences in a community-based cohort: The potential role of positive attributes as a protective factor. Schizophrenia Research 2018, 205: 23-29. PMID: 30879477, DOI: 10.1016/j.schres.2018.06.044.Peer-Reviewed Original ResearchConceptsChildhood traumaPsychotic experiencesPositive attributesSelf-reported psychotic experiencesIndirect effectsBaseline psychotic experiencesHigh childhood traumaMediation modelAdolescent psychotic experiencesYear old childrenPersonality characteristicsProtective factorsPreventive interventionsBehavioral traitsHigh levelsIndirect pathwaysChildrenTraumaPsychologistsAdolescenceExperienceParentsRelationshipAttributesTime pointsThe association between psychotic experiences and traumatic life events: the role of the intention to harm
Moriyama T, Drukker M, Gadelha A, Pan P, Salum G, Manfro G, de Jesus Mari J, Miguel E, Rohde L, Polanczyk G, van Os J, Bressan R. The association between psychotic experiences and traumatic life events: the role of the intention to harm. Psychological Medicine 2018, 48: 2235-2246. PMID: 29331167, DOI: 10.1017/s0033291717003762.Peer-Reviewed Original ResearchConceptsTraumatic life eventsPsychotic experiencesLife eventsType of traumaTraumatic exposureTraumatic experiencesPositive associationMental healthTrauma categoriesChildren's exposureIntentionGreater levelsAccount potential confoundersMethods of assessmentExperiencePsychologistsBullyingAdolescentsDose of exposureTraumaStrong associationClinical confoundersBiasesDemographic characteristicsPotential confounders
1997
Phenomenological differences appearing with repetitive behaviours in obsessive-compulsive disorder and Gilles de la Tourette's syndrome
Miguel E, Baer L, Coffey B, Rauch S, Savage C, O'Sullivan R, Phillips K, Moretti C, Leckman J, Jenike M. Phenomenological differences appearing with repetitive behaviours in obsessive-compulsive disorder and Gilles de la Tourette's syndrome. The British Journal Of Psychiatry 1997, 170: 140-145. PMID: 9093502, DOI: 10.1192/bjp.170.2.140.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderRepetitive behaviorsSensory phenomenaAutonomic anxietyMore cognitionsOCD groupGilles de la Tourette's syndromeOCD subtypesSubjective experienceGTS groupSemi-structured interviewsCognitionTourette syndromeValid predictorPhenomenological differencesAnxietyLa Tourette's syndromeAdult outpatientsPhenomenological studyDisordersBehaviorTreatment responsePredictorsInterviewsExperience