2020
Efficacy and Safety of Transcranial Direct Current Stimulation as a Treatment for Obsessive-Compulsive Disorder: A Randomized, Sham-Controlled Trial
Silva R, Brunoni A, Goerigk S, Batistuzzo M, Costa D, Diniz J, Padberg F, D'Urso G, Miguel E, Shavitt R. Efficacy and Safety of Transcranial Direct Current Stimulation as a Treatment for Obsessive-Compulsive Disorder: A Randomized, Sham-Controlled Trial. Biological Psychiatry 2020, 87: s127. DOI: 10.1016/j.biopsych.2020.02.342.Peer-Reviewed Original Research
2019
SU72 TRANSCRIPTOME STUDY IN OBSESSIVE COMPULSIVE DISORDERS
Lisboa B, Tahira A, Sant'Anna A, Oliveira K, Miguel E, Hoexter M, Farfel J, Brentani H. SU72 TRANSCRIPTOME STUDY IN OBSESSIVE COMPULSIVE DISORDERS. European Neuropsychopharmacology 2019, 29: s927. DOI: 10.1016/j.euroneuro.2017.08.261.Peer-Reviewed Original ResearchObsessive-compulsive disorderNucleus accumbensSubgenual cingulate gyrusCortico-striatal circuitryOrbitofrontal cortexAffective circuitryCingulate gyrusCaudate nucleusBrain areasCognitive circuitryBrazilian Aging Brain Study GroupCompulsive disorderEnsheathment of neuronsEnrichment analysisBackground Obsessive-compulsive disorderDrug metabolic processFunctional neuroimaging studiesCortico-striatal loopsDopaminergic synapsesBrain BankThalamic circuitryGene expressionStudy groupNeurological system processPsychiatric disorders
2011
Brazilian psychiatric brain bank: a new contribution tool to network studies
de Oliveira K, Nery F, Ferreti R, Lima M, Cappi C, Machado-Lima A, Polichiso L, Carreira L, Ávila C, Alho A, Brentani H, Miguel E, Heinsen H, Jacob-Filho W, Pasqualucci C, Lafer B, Grinberg L. Brazilian psychiatric brain bank: a new contribution tool to network studies. Cell And Tissue Banking 2011, 13: 315-326. PMID: 21562728, DOI: 10.1007/s10561-011-9258-0.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderBipolar disorderBrain BankBrazilian Aging Brain Study GroupMajor depressive disorderSubstance use disordersMood disorder NOSDepressive disorderStudy groupPsychiatric assessmentDisorder NOSUse disordersAverage ageAutopsy serviceNeuropsychiatric diseasesObsessive-compulsive spectrum symptomsOCD patientsOptimal fixationDisordersCompulsive disorderSpectrum symptomsBrainPsychiatric researchMolecular studiesUrgent needCognitive Dysfunction in Post-Traumatic Obsessive–Compulsive Disorder
Borges M, Braga D, Iêgo S, D'Alcante C, Sidrim I, Machado M, Pinto P, Cordioli A, do Rosário M, Petribú K, Mendlowicz M, Mari J, Miguel E, Fontenelle L. Cognitive Dysfunction in Post-Traumatic Obsessive–Compulsive Disorder. Australian & New Zealand Journal Of Psychiatry 2011, 45: 76-85. PMID: 21174503, DOI: 10.3109/00048674.2010.527822.Peer-Reviewed Original ResearchConceptsSet-shifting abilityObsessive-compulsive disorderPoor set-shifting abilitiesWechsler Memory Scale-Logical MemoryBrief Visual Memory TestWisconsin Card Sorting TestVisual memory testsIowa Gambling TaskCard Sorting TestFollowing neuropsychological testsWechsler Abbreviated ScaleTypes of OCDPosttraumatic stress disorderObsessive-compulsive symptomsMemory testVisuospatial memoryGambling TaskLogical memorySorting TestAbbreviated ScaleNeurocognitive patternsNeuropsychological testsStress disorderVisuospatial recognitionCompulsive disorder
2010
P.4.e.003 Clomipramine and quetiapine augmentation for obsessive compulsive disorder compared to sustained fluoxetine treatment
Diniz J, Pereira C, Miguel E, Shavitt R. P.4.e.003 Clomipramine and quetiapine augmentation for obsessive compulsive disorder compared to sustained fluoxetine treatment. European Neuropsychopharmacology 2010, 20: s547-s548. DOI: 10.1016/s0924-977x(10)70824-5.Peer-Reviewed Original ResearchResponse to Sham and Active Gamma Ventral Capsulotomy in Otherwise Intractable Obsessive-Compulsive Disorder
Gouvea F, Lopes A, Greenberg B, Canteras M, Taub A, Mathis M, Miguel E. Response to Sham and Active Gamma Ventral Capsulotomy in Otherwise Intractable Obsessive-Compulsive Disorder. Stereotactic And Functional Neurosurgery 2010, 88: 177-182. PMID: 20431329, DOI: 10.1159/000313870.Peer-Reviewed Original ResearchConceptsRefractory obsessive-compulsive disorderGamma ventral capsulotomyClinical responseSham surgeryObsessive-compulsive disorderSurgical techniquePsychopathological changesRadiosurgical proceduresRemarkable ameliorationActive interventionCompulsive disorderDisordersActive procedureCapsulotomySurgeryShamRadiosurgery
2006
Prenatal, Perinatal, and Postnatal Risk Factors in Obsessive–Compulsive Disorder
Vasconcelos M, Sampaio A, Hounie A, Akkerman F, Curi M, Lopes A, Miguel E. Prenatal, Perinatal, and Postnatal Risk Factors in Obsessive–Compulsive Disorder. Biological Psychiatry 2006, 61: 301-307. PMID: 17123475, DOI: 10.1016/j.biopsych.2006.07.014.Peer-Reviewed Original ResearchConceptsPostnatal risk factorsObsessive-compulsive disorderRisk factorsProlonged laborOCD patientsExcessive weight gainLogistic regression analysisEarly risk factorsHyperemesis gravidarumPreterm birthPrenatal careControl subjectsStandardized questionnaireControl groupWeight gainEdemaSocioeconomic classCompulsive disorderPregnancyPatientsRegression analysisGestationPerinatalGreater frequencyEnvironmental factors
2005
Chronic tics and Tourette syndrome in patients with obsessive–compulsive disorder
Diniz J, Rosario-Campos M, Hounie A, Curi M, Shavitt R, Lopes A, Miguel E. Chronic tics and Tourette syndrome in patients with obsessive–compulsive disorder. Journal Of Psychiatric Research 2005, 40: 487-493. PMID: 16289552, DOI: 10.1016/j.jpsychires.2005.09.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildChi-Square DistributionDiagnosis, DifferentialDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMaleMiddle AgedMultivariate AnalysisObsessive-Compulsive DisorderPersonality InventoryPsychiatric Status Rating ScalesPsychometricsRetrospective StudiesSeverity of Illness IndexTic DisordersTourette SyndromeConceptsObsessive-compulsive disorderTourette syndromeOCD patientsVocal ticsYale Global Tic Severity ScaleNumber of comorbiditiesStructured Clinical InterviewTic Severity ScaleYale-Brown Obsessive Compulsive ScaleObsessive Compulsive ScaleSymptom onsetChronic motorTic disordersCommon disorderSeverity ScalePatientsClinical InterviewChronic ticsDSM-IVBehaviors InterviewCompulsive ScaleSomatic obsessionsDisordersCompulsive disorderOCD phenotypeCitalopram plus reboxetine in treatment-resistant obsessive-compulsive disorder
Fontenelle L, Mendlowicz M, Miguel E, Versiani M. Citalopram plus reboxetine in treatment-resistant obsessive-compulsive disorder. The World Journal Of Biological Psychiatry 2005, 6: 57-59. PMID: 16097406, DOI: 10.1080/15622970510029740.Peer-Reviewed Original ResearchConceptsTreatment-resistant obsessive-compulsive disorderObsessive-compulsive disorderSRI-resistant obsessive compulsive disorderResistant obsessive-compulsive disorderCombination of citalopramFirst-line treatmentAdequate trialReuptake inhibitorsCompulsive disorderPatientsCitalopramDisordersFuture studiesTrials
1996
Obsessive compulsive disorder and Tourette syndrome in patients with rheumatic fever with or without Sydenham's chorea: phenomenological and laboratorial aspects.
Mercadante M, Miguel Filho E. Obsessive compulsive disorder and Tourette syndrome in patients with rheumatic fever with or without Sydenham's chorea: phenomenological and laboratorial aspects. Revista Da Associação Médica Brasileira 1996, 42: 61-2. PMID: 8935679.Peer-Reviewed Original Research