2020
Common Protective Strategies in Neurodegenerative Disease: Focusing on Risk Factors to Target the Cellular Redox System
Hrelia P, Sita G, Ziche M, Ristori E, Marino A, Cordaro M, Molteni R, Spero V, Malaguti M, Morroni F, Hrelia S. Common Protective Strategies in Neurodegenerative Disease: Focusing on Risk Factors to Target the Cellular Redox System. Oxidative Medicine And Cellular Longevity 2020, 2020: 8363245. PMID: 32832006, PMCID: PMC7422410, DOI: 10.1155/2020/8363245.Peer-Reviewed Original ResearchConceptsNeurodegenerative diseasesRisk factorsCellular redox systemsRedox homeostasisMolecular mechanismsMultiple risk factorsPivotal risk factorComplex multifactorial natureDisease mechanismsVascular injuryChronic neurodegenerationPreventive strategiesCommon mechanismOxidative stressMultifactorial natureDiseaseProtective strategiesHuman brainRedox systemProgressionComplex networksMechanismHomeostasisEarly stagesInflammation
2016
Studying Vascular Angiogenesis and Senescence in Zebrafish Embryos
Ristori E, Donnini S, Ziche M. Studying Vascular Angiogenesis and Senescence in Zebrafish Embryos. Methods In Molecular Biology 2016, 1430: 387-400. PMID: 27172969, DOI: 10.1007/978-1-4939-3628-1_27.Peer-Reviewed Original ResearchConceptsZebrafish embryosFluorescent transgenic linesCyclin-dependent kinase inhibitor p21 expressionVessel formationTransgenic linesSenescence defectsZebrafish modelPhosphatase activityAlkaline phosphatase activityEmbryosSenescenceExcellent animal modelExcellent disease modelZebrafishP21 expressionBrain degenerative changesNeurodegenerative diseasesVascular angiogenesisVascular senescenceΒ-galactosidaseOptical translucencyPeptide treatmentAmyloid β-peptideAngiogenesisDisease models