2001
Prophylaxis with Single-Dose Doxycycline for the Prevention of Lyme Disease after an Ixodes scapularis Tick Bite
Nadelman R, Nowakowski J, Fish D, Falco R, Freeman K, McKenna D, Welch P, Marcus R, Agüero-Rosenfeld M, Dennis D, Wormser G. Prophylaxis with Single-Dose Doxycycline for the Prevention of Lyme Disease after an Ixodes scapularis Tick Bite. New England Journal Of Medicine 2001, 345: 79-84. PMID: 11450675, DOI: 10.1056/nejm200107123450201.Peer-Reviewed Original ResearchConceptsDose of doxycyclineTick biteLyme diseaseErythema migransSingle-dose doxycyclinePlacebo-controlled trialFrequent adverse effectsMore frequent adverse effectsEfficacy of treatmentSerum antibody testsNymphal ticksAsymptomatic seroconversionPlacebo groupDoxycycline groupBlood culturesDegree of engorgementExtracutaneous signsI. scapularis ticksAntibody testAntimicrobial treatmentDiseaseAdverse effectsDoxycyclineBiteBorrelia burgdorferi
1999
Temporal Relation between Ixodes scapularis Abundance and Risk for Lyme Disease Associated with Erythema Migrans
Falco R, McKenna D, Daniels T, Nadelman R, Nowakowski J, Fish D, Wormser G. Temporal Relation between Ixodes scapularis Abundance and Risk for Lyme Disease Associated with Erythema Migrans. American Journal Of Epidemiology 1999, 149: 771-776. PMID: 10206627, DOI: 10.1093/oxfordjournals.aje.a009886.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnimalsErythema Chronicum MigransFemaleHumansIxodesLarvaLyme DiseaseNew YorkPopulation DensitySeasonsConceptsErythema migransLyme diseaseWestchester County Medical CenterLyme Disease AssociatedEarly Lyme diseaseCounty Medical CenterDisease prevention effortsYears of ageSuccessful prevention programsAdult ticksDisease AssociatedPrevention criteriaMedical CenterPatientsPrevention programsDisease controlPrevention effortsCase numbersI. scapularisDiseaseAdult I. scapularisEM casesEM incidenceAnnual numberMigrans