1994
NMR studies of human brain function
Shulman R, Rothman D, Blamire A. NMR studies of human brain function. Trends In Biochemical Sciences 1994, 19: 522-526. PMID: 7846759, DOI: 10.1016/0968-0004(94)90050-7.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingPositron emission tomographyUnstimulated subjectsResonance imagingEmission tomographyBrain functionHuman brain functionSensory stimulationVisual stimulationBrain activityHuman brain activityHuman brainStimulationMetabolic rateSignificant improvementMagnetic resonance spectroscopySingle subjectSubjectsEstablished method
1993
Localized 1H NMR measurement of glucose consumption in the human brain during visual stimulation.
Chen W, Novotny E, Zhu X, Rothman D, Shulman R. Localized 1H NMR measurement of glucose consumption in the human brain during visual stimulation. Proceedings Of The National Academy Of Sciences Of The United States Of America 1993, 90: 9896-9900. PMID: 8234332, PMCID: PMC47679, DOI: 10.1073/pnas.90.21.9896.Peer-Reviewed Original ResearchConceptsCerebral metabolic rateGlucose levelsPhotic stimulationBrain glucose concentrationsGlucose metabolic ratePrimary visual cortexAverage maximum changeMetabolic rateVisual cortex regionsBrain glucoseCalcarine fissureVisual cortexGlucose changesLactate concentrationCortex regionsVisual stimulationStimulationGlucose concentrationHuman brainGlucose consumptionGlucose transportIndividual subjectsMinCortexLevels