2001
Spectroscopic Assessment of Alterations in Macromolecule and Small-Molecule Metabolites in Human Brain After Stroke
Graham G, Hwang J, Rothman D, Prichard J. Spectroscopic Assessment of Alterations in Macromolecule and Small-Molecule Metabolites in Human Brain After Stroke. Stroke 2001, 32: 2797-2802. PMID: 11739976, DOI: 10.1161/hs1201.099414.Peer-Reviewed Original Research
1996
Short echo time proton magnetic resonance spectroscopic imaging of macromolecule and metabolite signal intensities in the human brain
Hwang J, Graham G, Behar K, Alger J, Prichard J, Rothman D. Short echo time proton magnetic resonance spectroscopic imaging of macromolecule and metabolite signal intensities in the human brain. Magnetic Resonance In Medicine 1996, 35: 633-639. PMID: 8722812, DOI: 10.1002/mrm.1910350502.Peer-Reviewed Original ResearchConceptsSubacute stroke patientsProton magnetic resonance spectroscopicProton magnetic resonance spectroscopic imagingMagnetic resonance spectroscopic imagingStroke patientsHealthy subjectsMagnetic resonance spectroscopicMetabolite signal intensitiesBrain regionsPathological conditionsMacromolecule resonancesHuman brainBrainSignal intensitySubjectsRecovery timeSpectroscopic imagingPatients
1994
Proton spectroscopy of human stroke: Assessment of transverse relaxation times and partial volume effects in single volume STEAM MRS
Blamire A, Graham G, Rothman D, Prichard J. Proton spectroscopy of human stroke: Assessment of transverse relaxation times and partial volume effects in single volume STEAM MRS. Magnetic Resonance Imaging 1994, 12: 1227-1235. PMID: 7854028, DOI: 10.1016/0730-725x(94)90087-8.Peer-Reviewed Original ResearchConceptsStroke patientsAge-matched normal subjectsHuman strokeSpin-echo MRINormal subjectsNormal brainPatientsInfarcted tissueProton T2 relaxation timesInverse correlationHigh inverse correlationT2 relaxation timesCholine resonanceSignificant differencesProton spectroscopyPercentage volumeT2 valuesT. SpectraPartial volume effectsPeak amplitudeSTEAM sequence
1992
Proton magnetic resonance spectroscopy of cerebral lactate and other metabolites in stroke patients.
Graham G, Blamire A, Howseman A, Rothman D, Fayad P, Brass L, Petroff O, Shulman R, Prichard J. Proton magnetic resonance spectroscopy of cerebral lactate and other metabolites in stroke patients. Stroke 1992, 23: 333-340. PMID: 1542892, DOI: 10.1161/01.str.23.3.333.Peer-Reviewed Original ResearchConceptsProton magnetic resonance spectroscopyStroke patientsCerebral lactateDeep cerebral infarctsElevated cerebral lactateSmall subcortical infarctsCortical stroke patientsN-acetylaspartate levelsLong-term elevationCerebral infarctsCortical strokeOngoing ischemiaSymptom onsetBrain lactateElevated lactateInitial insultSubcortical infarctsN-acetylaspartateInfarct regionLesion onsetMagnetic resonance spectroscopyInfarctsPatientsFirst weekStroke