1997
Spontaneous, pH-Dependent Membrane Insertion of a Transbilayer α-Helix †
Hunt J, Rath P, Rothschild K, Engelman D. Spontaneous, pH-Dependent Membrane Insertion of a Transbilayer α-Helix †. Biochemistry 1997, 36: 15177-15192. PMID: 9398245, DOI: 10.1021/bi970147b.Peer-Reviewed Original ResearchConceptsLipid bilayersIntegral membrane protein bacteriorhodopsinMembrane-spanning regionIntegral membrane proteinsPH-dependent membrane insertionAspartic acid residuesMembrane protein bacteriorhodopsinInsertion reactionMembrane insertionMembrane proteinsAqueous solutionHydrophobic sequenceAqueous bufferPoor solubilityAlpha-helixAcid residuesSignificant solubilityC-helixSpectroscopic assaysΑ-helixSecondary structureProtein bacteriorhodopsinNeutral pHPeptide associatesBilayersAssessment of the aggregation state of integral membrane proteins in reconstituted phospholipid vesicles using small angle neutron scattering11Edited by M. F. Moody
Hunt J, McCrea P, Zaccaı̈ G, Engelman D. Assessment of the aggregation state of integral membrane proteins in reconstituted phospholipid vesicles using small angle neutron scattering11Edited by M. F. Moody. Journal Of Molecular Biology 1997, 273: 1004-1019. PMID: 9367787, DOI: 10.1006/jmbi.1997.1330.Peer-Reviewed Original ResearchConceptsMembrane protein complexesIntegral membrane proteinsProtein complexesMembrane proteinsIntegral membrane protein complexPhospholipid vesiclesSmall unilamellar phospholipid vesiclesUnilamellar phospholipid vesiclesMolecular massF. MoodySpatial arrangementNon-ionic detergentIndividual complexesVesiclesModel systemMonomeric bacteriorhodopsinProteinUnknown scopeComplexesAggregation stateRadius of gyrationBacteriorhodopsinDetergentsBilayers
1975
The use of x-ray scattering in the study of lipid bilayer planar organization
Engelman D. The use of x-ray scattering in the study of lipid bilayer planar organization. Biophysical Journal 1975, 15: 940-944. PMID: 1182268, PMCID: PMC1334757, DOI: 10.1016/s0006-3495(75)85871-1.Peer-Reviewed Original Research
1972
Molecular Mechanism for the Interaction of Phospholipid with Cholesterol
ROTHMAN J, ENGELMAN D. Molecular Mechanism for the Interaction of Phospholipid with Cholesterol. Nature 1972, 237: 42-44. PMID: 4503742, DOI: 10.1038/newbio237042a0.Peer-Reviewed Original Research
1971
Bilayer Structure in Membranes
WILKINS M, BLAUROCK A, ENGELMAN D. Bilayer Structure in Membranes. Nature 1971, 230: 72-76. PMID: 5279041, DOI: 10.1038/newbio230072a0.Peer-Reviewed Original Research
1969
CURRENT MODELS FOR THE STRUCTURE OF BIOLOGICAL MEMBRANES
Stoeckenius W, Engelman D. CURRENT MODELS FOR THE STRUCTURE OF BIOLOGICAL MEMBRANES. Journal Of Cell Biology 1969, 42: 613-646. PMID: 4895596, PMCID: PMC2107701, DOI: 10.1083/jcb.42.3.613.Peer-Reviewed Original Research