Multiscale geometric and topological analyses for characterizing and predicting immune responses from single cell data
Venkat A, Bhaskar D, Krishnaswamy S. Multiscale geometric and topological analyses for characterizing and predicting immune responses from single cell data. Trends In Immunology 2023, 44: 551-563. PMID: 37301677, DOI: 10.1016/j.it.2023.05.003.Peer-Reviewed Original ResearchConceptsTopological propertiesMultiscale approachLarge-scale data setsSingle-cell dataCell methodTopological featuresMultiple scalesTopological data analysis of spatial patterning in heterogeneous cell populations: clustering and sorting with varying cell-cell adhesion
Bhaskar D, Zhang W, Volkening A, Sandstede B, Wong I. Topological data analysis of spatial patterning in heterogeneous cell populations: clustering and sorting with varying cell-cell adhesion. Npj Systems Biology And Applications 2023, 9: 43. PMID: 37709793, PMCID: PMC10502054, DOI: 10.1038/s41540-023-00302-8.Peer-Reviewed Original ResearchConceptsTopological data analysisPersistence imagesClassification accuracyHigh classification accuracyMachine learningRobust classificationDimensionality reductionUnsupervised classificationHierarchical architectureData analysisArchitectureHierarchical clusteringImagesTopological featuresClassificationDifferent topological featuresAutoencoderAccuracyClusteringLearningSimulationsInformationRecent developments