2024
215P Differential spatial gene expression and clinicopathologic characteristics are associated with exceptional response to immune checkpoint inhibition in recurrent/metastatic head and neck cancer
Gavrielatou N, Spathis A, Anastasiou M, Economopoulou P, Foukas G, Lelegiannis I, Aung T, Kotsantis I, Vagia E, Panayiotides I, Rimm D, Foukas P, Psyrri A. 215P Differential spatial gene expression and clinicopathologic characteristics are associated with exceptional response to immune checkpoint inhibition in recurrent/metastatic head and neck cancer. Immuno-Oncology Technology 2024, 24: 100968. DOI: 10.1016/j.iotech.2024.100968.Peer-Reviewed Original Research
2020
Biomarkers in Precision Cancer Immunotherapy: Promise and Challenges.
McKean WB, Moser JC, Rimm D, Hu-Lieskovan S. Biomarkers in Precision Cancer Immunotherapy: Promise and Challenges. American Society Of Clinical Oncology Educational Book 2020, 40: e275-e291. PMID: 32453632, DOI: 10.1200/edbk_280571.Peer-Reviewed Original ResearchConceptsHost immune defectsPrecision cancer immunotherapyHealth care burdenCurrent treatment modalitiesSignificant side effectsSustained remissionClinical responseCheckpoint inhibitionImmune defectsRefractory malignanciesCancer immunotherapeuticsClinical benefitPatient survivalCancer immunotherapyPredictive biomarkersTreatment modalitiesCare burdenPatient responseSide effectsTrial designTumor parenchymaClinical useBiomarker developmentBiomarkersMultiple biomarkers