2024
Life's Essential 8 and Poor Brain Health Outcomes in Middle-Aged Adults
Clocchiatti-Tuozzo S, Rivier C, Renedo D, Huo S, Hawkes M, de Havenon A, Schwamm L, Sheth K, Gill T, Falcone G. Life's Essential 8 and Poor Brain Health Outcomes in Middle-Aged Adults. Neurology 2024, 103: e209990. PMID: 39442069, PMCID: PMC11498939, DOI: 10.1212/wnl.0000000000209990.Peer-Reviewed Original ResearchConceptsLife's Essential 8Poor cardiovascular healthCardiovascular healthBrain healthLife's Essential 8 scoreUnadjusted riskEssential 8Determinants of cardiovascular healthUK Biobank (UKBCardiovascular health profileModifiable cardiovascular risk factorsBrain health outcomesRisk factorsComposite outcomePublic health constructsPopulation studiesMiddle-aged adultsCox modelLate-life depressionCox proportional hazards modelsBrain health benefitsMultivariate Cox modelCardiovascular risk factorsFollow-up timeAoU participantsIn Reply to the Letter to the Editor Regarding “Risk Factors Related to Transient Diabetes Insipidus Development Following Transsphenoidal Pituitary Adenoma Resection: A Multicentric Study”
Yasuda M, Renedo D, Recalde R, Zaninovich R, Gonzalez Abbati S, Cervio A, Giovannini S, Villalonga J, Ulloque-Caamaño L, Reddy K, Socolovsky M, Campero A. In Reply to the Letter to the Editor Regarding “Risk Factors Related to Transient Diabetes Insipidus Development Following Transsphenoidal Pituitary Adenoma Resection: A Multicentric Study”. World Neurosurgery 2024, 185: 484. PMID: 38741317, DOI: 10.1016/j.wneu.2024.01.175.Peer-Reviewed Original Research
2023
Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses
Renedo D, Acosta J, Koo A, Rivier C, Sujijantarat N, de Havenon A, Sharma R, Gill T, Sheth K, Falcone G, Matouk C. Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses. Stroke 2023, 54: 1538-1547. PMID: 37216451, PMCID: PMC10212531, DOI: 10.1161/strokeaha.122.041891.Peer-Reviewed Original ResearchMeSH KeywordsHemorrhagic StrokeHospitalsHumansPopulation HealthRetrospective StudiesRisk FactorsStrokeConceptsHospital Frailty Risk ScoreRisk of strokeHighest Hospital Frailty Risk ScoresDate of consentFrailty Risk ScoreMendelian randomization analysisStroke riskRisk scoreRandomization analysisTime of enrollmentAvailable electronic health recordsMendelian randomizationElectronic health recordsLook-back periodIncident strokeDose-response wayFrailty statusHemorrhagic strokeMultivariable analysisStroke eventsObservational studyHigh riskFrailtySignificant associationSimilar associationRisk Factors Related to Transient Diabetes Insipidus Development Following Transsphenoidal Pituitary Adenoma Resection: A Multicentric Study
Yasuda M, Renedo D, Sosa S, Danilowicz K, Recalde R, Zaninovich R, Abbati S, Cervio A, Giovannini S, Villalonga J, Ulloque-Caamaño L, Reddy K, Socolovsky M, Campero A. Risk Factors Related to Transient Diabetes Insipidus Development Following Transsphenoidal Pituitary Adenoma Resection: A Multicentric Study. World Neurosurgery 2023, 175: e636-e643. PMID: 37030477, DOI: 10.1016/j.wneu.2023.03.150.Peer-Reviewed Original ResearchConceptsGross total resectionTrans-sphenoidal surgeryPituitary adenoma resectionRisk factorsPostoperative DITotal resectionAdenoma resectionMultivariable modelFemale genderTranssphenoidal pituitary adenoma resectionMultivariate logistic regression modelDifferent neurosurgical centersMulticenter case seriesIndependent risk factorMean tumor sizeSignificant predictorsLogistic regression analysisLogistic regression modelsTransient DITransient diabetesYounger patientsCase seriesMean ageTumor sizeMulticentric study
2022
Response to letter to the Editor on ‘Utility of the Hospital Frailty Risk Score in patients undergoing endovascular treatment for ruptured aneurysms’
Koo A, Elsamadicy A, Renedo D, Matouk C. Response to letter to the Editor on ‘Utility of the Hospital Frailty Risk Score in patients undergoing endovascular treatment for ruptured aneurysms’. Journal Of NeuroInterventional Surgery 2022, 15: 307-308. PMID: 36319084, DOI: 10.1136/jnis-2022-019708.Peer-Reviewed Original ResearchHospital Frailty Risk Score Predicts Adverse Events and Readmission Following a Ventriculoperitoneal Shunt Surgery for Normal Pressure Hydrocephalus
Koo AB, Elsamadicy AA, Renedo D, Sarkozy M, Reeves BC, Barrows MM, Hengartner A, Havlik J, Sandhu MRS, Antonios JP, Malhotra A, Matouk CC. Hospital Frailty Risk Score Predicts Adverse Events and Readmission Following a Ventriculoperitoneal Shunt Surgery for Normal Pressure Hydrocephalus. World Neurosurgery 2022, 170: e9-e20. PMID: 35970293, DOI: 10.1016/j.wneu.2022.08.037.Peer-Reviewed Original ResearchConceptsHospital Frailty Risk ScoreFrailty Risk ScoreVP shunt surgeryVentriculoperitoneal shunt surgeryAdverse eventsShunt surgeryIndependent predictorsNPH patientsRisk scoreHealth care resource utilizationMultivariate logistic regression analysisNormal pressure hydrocephalus patientsRetrospective cohort studyNationwide Readmissions DatabaseNormal pressure hydrocephalusLogistic regression analysisRegression analysisMultivariate regression analysisUnplanned readmissionCohort studyHospital readmissionPressure hydrocephalusAdmission costsReadmissionHydrocephalus patientsHigher Hospital Frailty Risk Score is associated with increased complications and healthcare resource utilization after endovascular treatment of ruptured intracranial aneurysms
Koo AB, Elsamadicy AA, Renedo D, Sarkozy M, Sherman J, Reeves BC, Havlik J, Antonios J, Sujijantarat N, Hebert R, Malhotra A, Matouk C. Higher Hospital Frailty Risk Score is associated with increased complications and healthcare resource utilization after endovascular treatment of ruptured intracranial aneurysms. Journal Of NeuroInterventional Surgery 2022, 15: 255-261. PMID: 35292571, PMCID: PMC8931798, DOI: 10.1136/neurintsurg-2021-018484.Peer-Reviewed Original ResearchConceptsHospital Frailty Risk ScoreNon-routine dischargeLength of stayFrailty Risk ScoreHealthcare resource utilizationTotal hospital costsEndovascular treatmentIntracranial aneurysmsAdverse eventsHospital costsRisk scoreHighest Hospital Frailty Risk ScoresMean LOSNational Inpatient Sample databaseMean total hospital costMultivariate logistic regression analysisImpact of frailtyRetrospective cohort studyICD-10-CM codesLogistic regression analysisRegression analysisMultivariate regression analysisCohort studyDischarge dispositionPatient demographics