2000
A new twist in trypanosome RNA metabolism: cis-splicing of pre-mRNA.
Mair G, Shi H, Li H, Djikeng A, Aviles H, Bishop J, Falcone F, Gavrilescu C, Montgomery J, Santori M, Stern L, Wang Z, Ullu E, Tschudi C. A new twist in trypanosome RNA metabolism: cis-splicing of pre-mRNA. RNA 2000, 6: 163-9. PMID: 10688355, PMCID: PMC1369902, DOI: 10.1017/s135583820099229x.Peer-Reviewed Original ResearchConceptsCis-spliced intronsSplice siteGT/AG ruleSmall intergenic regionAncient acquisitionGene arrangementTrypanosome genomeEukaryotic cellsRNA metabolismIntergenic regionIntron removalLeader sequenceTrypanosoma bruceiIntronsNucleotide positionsAG dinucleotideEuglena gracilisTrypanosoma cruziPolymerase geneIdentical positionsPoint mutationsRecent discoveryPAP mRNAGenesMRNA
1988
Polygene transcripts are precursors to calmodulin mRNAs in trypanosomes.
Tschudi C, Ullu E. Polygene transcripts are precursors to calmodulin mRNAs in trypanosomes. The EMBO Journal 1988, 7: 455-463. PMID: 3366120, PMCID: PMC454342, DOI: 10.1002/j.1460-2075.1988.tb02833.x.Peer-Reviewed Original ResearchConceptsCalmodulin mRNACultured procyclic trypanosomesAbundant RNA speciesSteady-state RNAPulse-labeled RNAAuthentic precursorIntergenic regionRNA speciesProcyclic trypanosomesCalmodulin genePolyadenylation sitesAfrican trypanosomesHybridization probesTranscriptsStreptavidin-agaroseDiscrete endsSmall familyTrypanosomesMRNAGenesRNASpeciesCalmodulinTrypanosoma brucei gambienseBrucei gambiense