2023
Sleep dysfunction mediates the relationship between hypothalamic-insula connectivity and anxiety-depression symptom severity bidirectionally in young adults
Li G, Chen Y, Chaudhary S, Li C, Hao D, Yang L, Li C. Sleep dysfunction mediates the relationship between hypothalamic-insula connectivity and anxiety-depression symptom severity bidirectionally in young adults. NeuroImage 2023, 279: 120340. PMID: 37611815, DOI: 10.1016/j.neuroimage.2023.120340.Peer-Reviewed Original ResearchConceptsPittsburgh Sleep Quality IndexRight insulaSymptom severityMediation analysisSleep dysfunctionWhole-brain regressionHuman Connectome Project datasetSubjective mood stateYoung adultsState functional connectivityDepression symptom severityNegative emotionsCognitive performanceEmotional deficitsEmotional statesPotential sex differencesAffective functionsDrinking severityMood statesMotivated behaviorFunctional connectivityPoor sleep qualityRSFCSleep Quality IndexSleep quality
2022
Overnight Abstinence Is Associated With Smaller Secondary Somatosensory Cortical Volumes and Higher Somatosensory-Motor Cortical Functional Connectivity in Cigarette Smokers
Chen Y, Dhingra I, Chaudhary S, Fucito L, Li CR. Overnight Abstinence Is Associated With Smaller Secondary Somatosensory Cortical Volumes and Higher Somatosensory-Motor Cortical Functional Connectivity in Cigarette Smokers. Nicotine & Tobacco Research 2022, 24: 1889-1897. PMID: 35796689, PMCID: PMC9653081, DOI: 10.1093/ntr/ntac168.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityGray matter volumeWithdrawal symptom severityOvernight abstinenceFunctional connectivityRight SIISymptom severityCigarette smokersSomatosensory cortexMatter volumeRight secondary somatosensory cortexSmaller gray matter volumeSubcortical gray matter volumesSecond somatosensory cortexSecondary somatosensory cortexCortical functional connectivityMotor impulsivityVoxel-wise morphometryRegional gray matter volumeLeft ventral hippocampusGMV alterationsCigarette smokingSatiety stateAbstinence symptomsHigher-order sensory cortices
2021
Sex differences in attention deficit hyperactivity symptom severity and functional connectivity of the dorsal striatum in young adults
Chen Y, Li G, Ide J, Luo X, Li C. Sex differences in attention deficit hyperactivity symptom severity and functional connectivity of the dorsal striatum in young adults. Neuroimage Reports 2021, 1: 100025. DOI: 10.1016/j.ynirp.2021.100025.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderADHD total scoreGroup 2Functional connectivityDorsal striatumGroup 3Symptom severityGroup 1Sex differencesTotal scoreFrontal gyrusRight inferior parietal gyrusRight superior frontal gyrusBasal ganglia dysfunctionCaudate functional connectivitySupplementary motor areaDorsal anterior cingulate cortexAnterior cingulate cortexSeed-based correlationSuperior frontal gyrusGreater symptom severityInferior parietal gyrusDeficit hyperactivity disorderGanglia dysfunctionInferior frontal gyrus
2016
The symptom trajectories to clinical remission in Chinese patients with unipolar major depressive disorder
Cao Y, Shen J, Li W, Zhang Y, Guo X, Li C, Zhang Y, Luo X. The symptom trajectories to clinical remission in Chinese patients with unipolar major depressive disorder. Asia-Pacific Psychiatry 2016, 8: 309-311. PMID: 27015764, PMCID: PMC5035708, DOI: 10.1111/appy.12240.Peer-Reviewed Original ResearchConceptsClinical remissionChinese patientsSymptom trajectoriesUnipolar major depressive disorderMajor depressive disorder symptomsWeeks of assessmentMajor depressive disorderTreatment of fluoxetineDepressive disorder symptomsDepressive disorderTreatment responseProminent symptomWeek 1Psychomotor retardationRemissionSymptom severityPatientsDisorder symptomsFluoxetineSymptomsSeverityWeeksTreatmentOutpatientsShow heterogeneity