2000
Outcome of Children in the Indomethacin Intraventricular Hemorrhage Prevention Trial
Ment L, Vohr B, Allan W, Westerveld M, Sparrow S, Schneider K, Katz K, Duncan C, Makuch R. Outcome of Children in the Indomethacin Intraventricular Hemorrhage Prevention Trial. Pediatrics 2000, 105: 485-491. PMID: 10699097, DOI: 10.1542/peds.105.3.485.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Inflammatory Agents, Non-SteroidalBrain Damage, ChronicCerebral HemorrhageCerebral VentriclesChild, PreschoolDose-Response Relationship, DrugFemaleFollow-Up StudiesHumansIndomethacinInfantInfant, NewbornInfant, Premature, DiseasesMaleNeurologic ExaminationNeuropsychological TestsPregnancyConceptsLow-dose indomethacinIntraventricular hemorrhagePlacebo childrenIndomethacin therapyPreterm infantsEarly administrationNeurologic examinationPrevention trialsLow birth weight preterm infantsStudy childrenBirth weight preterm infantsSeverity of IVHLow birth weight survivorsMean gestational ageWeight preterm infantsAdverse neurodevelopmental outcomesOutcome of childrenStandard neurologic examinationYears of ageNeurodevelopmental handicapPreterm neonatesNeurodevelopmental examinationNeurodevelopmental outcomesCerebral palsyGestational age
1996
Neurodevelopmental outcome at 36 months' corrected age of preterm infants in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial.
Ment L, Vohr B, Oh W, Scott D, Allan W, Westerveld M, Duncan C, Ehrenkranz R, Katz K, Schneider K, Makuch R. Neurodevelopmental outcome at 36 months' corrected age of preterm infants in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial. Pediatrics 1996, 98: 714-8. PMID: 8885951, DOI: 10.1542/peds.98.4.714.Peer-Reviewed Original ResearchMeSH KeywordsCerebral HemorrhageChild DevelopmentChild, PreschoolChi-Square DistributionCyclooxygenase InhibitorsHumansIndomethacinInfantInfant, NewbornInfant, PrematureInfant, Premature, DiseasesInfant, Very Low Birth WeightIntelligence TestsNeurologic ExaminationUltrasonography, Doppler, TranscranialConceptsLow-dose indomethacinMonths' corrected ageIntraventricular hemorrhageCorrected ageNeurodevelopmental followLong-term neurodevelopmental followLow birth weight infantsLow birth weight neonatesBirth weight infantsMean gestational ageBirth weight neonatesStandard neurologic examinationAdverse cognitive outcomesIncidence of deafnessDose indomethacinWeight infantsPreterm infantsProspective trialWeight neonatesCranial ultrasoundEarly administrationNeurodevelopmental outcomesNeurologic examinationCerebral palsyGestational age
1994
Low-dose indomethacin therapy and extension of intraventricular hemorrhage: A multicenter randomized trial
Ment L, Oh W, Ehrenkranz R, Phillip A, Vohr B, Allan W, Makuch R, Taylor K, Schneider K, Katz K, Scott D, Duncan C. Low-dose indomethacin therapy and extension of intraventricular hemorrhage: A multicenter randomized trial. The Journal Of Pediatrics 1994, 124: 951-955. PMID: 8201485, DOI: 10.1016/s0022-3476(05)83191-9.Peer-Reviewed Original ResearchConceptsLow-grade intraventricular hemorrhageIntraventricular hemorrhageAdverse eventsBirth weightLow birth weight infantsDistribution of hemorrhageGrade intraventricular hemorrhageBirth weight infantsPlacebo-controlled trialPercentage of infantsPatent ductus arteriosusGm birth weightHours of ageIndomethacin therapyWeight infantsApgar scoreParenchymal involvementSaline placeboDuctus arteriosusGestational ageIntracranial hemorrhagePostnatal hoursCascade of eventsPatent ductusCranial sonograms
1993
Risk period for intraventricular hemorrhage of the preterm neonate is independent of gestational age.
Ment L, Oh W, Ehrenkranz R, Philip A, Schneider K, Katz K, Taylor K, Duncan C, Makuch R. Risk period for intraventricular hemorrhage of the preterm neonate is independent of gestational age. Seminars In Perinatology 1993, 17: 338-41. PMID: 8290976.Peer-Reviewed Original Research
1992
Risk factors for early intraventricular hemorrhage in low birth weight infants
Ment L, Oh W, Philip A, Ehrenkranz R, Duncan C, Allan W, Taylor K, Schneider K, Katz K, Makuch R. Risk factors for early intraventricular hemorrhage in low birth weight infants. The Journal Of Pediatrics 1992, 121: 776-783. PMID: 1432433, DOI: 10.1016/s0022-3476(05)81915-8.Peer-Reviewed Original ResearchConceptsGMH/IVHBirth weightRisk factorsIntraventricular hemorrhageLow birth weight infantsBirth weight infantsMaternal risk factorsGm birth weightMore vaginal deliveriesIndependent prognostic indicatorGerminal matrix hemorrhageHigh-grade hemorrhageRisk factor dataGroups of infantsMode of deliveryEarly intraventricular hemorrhagePrimary hospitalizationSevere IVHTocolytic useWeight infantsPreterm infantsVaginal deliveryVertex presentationGestational ageIVH group
1988
Randomized low-dose indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight neonates
Ment L, Duncan C, Ehrenkranz R, Kleinman C, Taylor K, Scott D, Gettner P, Sherwonit E, Williams J. Randomized low-dose indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight neonates. The Journal Of Pediatrics 1988, 112: 948-955. PMID: 3373405, DOI: 10.1016/s0022-3476(88)80225-7.Peer-Reviewed Original ResearchConceptsIntraventricular hemorrhageGerminal matrixPostnatal hoursUrinary outputDay 5Placebo-controlled prospective trialLow birth weight neonatesDuctus arteriosus shuntIndomethacin-treated infantsSerum indomethacin levelsBirth weight neonatesCardiac ultrasound studiesAdequate urinary outputGroups of infantsIndomethacin trialStudy medicationApgar scorePreterm neonatesProspective trialWeight neonatesDuctus arteriosusGestational ageSerum electrolytesBirth weightPatent ductus
1985
Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants
Ment L, Duncan C, Ehrenkranz R, Kleinman C, Pitt B, Taylor J, Scott D, Stewart W, Gettner P. Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants. The Journal Of Pediatrics 1985, 107: 937-943. PMID: 3906073, DOI: 10.1016/s0022-3476(85)80197-9.Peer-Reviewed Original ResearchConceptsNeonatal intraventricular hemorrhageIntraventricular hemorrhagePostnatal hoursDuctus arteriosusLow birth weight infantsIndomethacin-treated groupIndomethacin-treated infantsPlacebo-treated patientsBirth weight infantsInitiation of therapyPatent ductus arteriosusCardiac ultrasound studiesIndomethacin trialApgar scoreWeight infantsPreterm neonatesControl infantsGestational ageOverall incidenceCerebral microvasculatureSerum electrolytesUrinary outputBirth weightClotting functionsUltrasound studyPerinatal Cerebral Insults: Hemorrhage and Ischemia
Ment L, Duncan C, Stewart W. Perinatal Cerebral Insults: Hemorrhage and Ischemia. Pediatric Neurosurgery 1985, 12: 168-174. PMID: 3916368, DOI: 10.1159/000120242.Peer-Reviewed Original ResearchConceptsMajor neurodevelopmental handicapsCerebral blood flowNeurodevelopmental handicapParenchymal involvementCerebral infarctionPreterm infantsIntraventricular hemorrhageGestational ageIschemic insultPerinatal careHigh riskBlood flowHemorrhageInfantsDevelopmental abnormalitiesCareInfarctionIschemiaNeonatesLesionsAbnormalitiesIncidenceInsultSurvivorsBrain