2024
A Digital Cognitive Behavioral Therapy Program for Adults With Alcohol Use Disorder
Kiluk B, Benitez B, DeVito E, Frankforter T, LaPaglia D, O’Malley S, Nich C. A Digital Cognitive Behavioral Therapy Program for Adults With Alcohol Use Disorder. JAMA Network Open 2024, 7: e2435205. PMID: 39325452, PMCID: PMC11428014, DOI: 10.1001/jamanetworkopen.2024.35205.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyDigital cognitive behavioral therapyAlcohol use disorderAlcohol useCBT programUse disorderCognitive behavioral therapy programCurrent alcohol use disorderTreatment-seeking adultsBehavioral therapy programEvidence-based treatmentsBaseline to 6-month follow-upRates of alcohol useReducing alcohol useTreatment periodRandomized clinical trialsBehavioral therapyOutpatient substancePercentage of daysOutpatient treatmentIntention-to-treat analysisIndividual counselingStudy periodFollow-upIntention-to-treat
2023
Percentage of negative urine drug screens as a clinically meaningful endpoint for RCTs evaluating treatment for cocaine use
Loya J, Babuscio T, Nich C, Alessi S, Rash C, Kiluk B. Percentage of negative urine drug screens as a clinically meaningful endpoint for RCTs evaluating treatment for cocaine use. Drug And Alcohol Dependence 2023, 248: 109947. PMID: 37276806, PMCID: PMC10498479, DOI: 10.1016/j.drugalcdep.2023.109947.Peer-Reviewed Original ResearchConceptsUrine drug screensClinical trialsMeaningful endpointsCocaine useLong-term clinical benefitBetter long-term outcomesDrug screensPsychosocial functioningNegative urine drug screensLong-term outcomesRandomized clinical trialsFuture clinical trialsBetter psychosocial functioningClinical benefitPharmacological treatmentContinuous abstinenceTreatment periodTreatment respondersSustained abstinenceSubstance useTrialsTreatmentMeaningful thresholdPooled datasetAbstinence
2019
Changes in DSM criteria following a culturally-adapted computerized CBT for Spanish-speaking individuals with substance use disorders
Silva MA, Jaramillo Y, Paris M, Añez-Nava L, Frankforter TL, Kiluk BD. Changes in DSM criteria following a culturally-adapted computerized CBT for Spanish-speaking individuals with substance use disorders. Journal Of Substance Use And Addiction Treatment 2019, 110: 42-48. PMID: 31952627, PMCID: PMC6981257, DOI: 10.1016/j.jsat.2019.12.006.Peer-Reviewed Original ResearchConceptsSubstance use disordersAddiction Severity IndexUse disordersDSM criteriaStructured Clinical InterviewDSM-IV substance dependenceMeaningful outcomesDiagnostic statusTimeline followback methodStatistical Manual criteriaCognitive behavioral therapy programBehavioral therapy programSubstance use outcomesProblem severityDSM-IV dependence criteriaPrimary outcomeUrine toxicologyLower problem severityClinical trialsTreatment periodMain trialOutpatient counselingClinical InterviewSecondary analysisDSM-IV
2017
Effect of computerized cognitive behavioral therapy on acquisition of coping skills among cocaine-dependent individuals enrolled in methadone maintenance
Kiluk BD, DeVito EE, Buck MB, Hunkele K, Nich C, Carroll KM. Effect of computerized cognitive behavioral therapy on acquisition of coping skills among cocaine-dependent individuals enrolled in methadone maintenance. Journal Of Substance Use And Addiction Treatment 2017, 82: 87-92. PMID: 29021121, PMCID: PMC5687291, DOI: 10.1016/j.jsat.2017.09.011.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyCocaine-dependent individualsHigh-risk situationsBehavioral therapyVerbal responsesComputerized cognitive behavioral therapyAbstinence outcomesComputerized CBT programParticipants' verbal responsesRole-play assessmentComputer-based trainingCertain high-risk situationsStandard methadone treatmentSubstance use disordersConsistent statistical supportCBT programMethadone treatmentMethadone maintenanceDependent individualsPlay assessmentPrior findingsClinical trialsTreatment periodUse disordersSubstance users
2016
Randomized Trial of Computerized Cognitive Behavioral Therapy for Alcohol Use Disorders: Efficacy as a Virtual Stand‐Alone and Treatment Add‐On Compared with Standard Outpatient Treatment
Kiluk BD, Devore KA, Buck MB, Nich C, Frankforter TL, LaPaglia DM, Yates BT, Gordon MA, Carroll KM. Randomized Trial of Computerized Cognitive Behavioral Therapy for Alcohol Use Disorders: Efficacy as a Virtual Stand‐Alone and Treatment Add‐On Compared with Standard Outpatient Treatment. Alcohol Clinical And Experimental Research 2016, 40: 1991-2000. PMID: 27488212, PMCID: PMC5008977, DOI: 10.1111/acer.13162.Peer-Reviewed Original ResearchConceptsAlcohol use disorderCognitive behavioral therapyComputerized cognitive behavioral therapyAlcohol useUse disordersClinical monitoringBehavioral therapyCurrent alcohol use disorderStandard outpatient treatmentEvidence-based treatmentsWeb-based CBT programPercentage of daysRandomized trialsPreliminary efficacyStandard treatmentOutpatient treatmentTreatment completionTreatment periodOutpatient facilitiesParticipants' alcohol useClinical practiceCBT4CBTCBT programTreatment-seeking individualsClinical samples
2015
Outcome expectations and associated treatment outcomes in motivational enhancement therapy delivered in English and Spanish
Serafini K, Decker S, Kiluk BD, Añez L, Paris M, Frankforter T, Carroll KM. Outcome expectations and associated treatment outcomes in motivational enhancement therapy delivered in English and Spanish. American Journal On Addictions 2015, 24: 732-739. PMID: 26541501, PMCID: PMC4885684, DOI: 10.1111/ajad.12301.Peer-Reviewed Original ResearchConceptsPatients' outcome expectationsTreatment outcomesMotivational enhancement therapyEnhancement therapyUrine toxicology screenLikelihood of abstinenceSubstance use disordersSubstance use outcomesToxicology screenClinical trialsTreatment periodUse disordersOutcome expectationsSecondary analysisSubstance useAbstinenceUse outcomesOutcomesMetSTherapyTreatmentBaseline expectationsGreater percentageSame treatmentImportant predictor