2022
Persistent organic pollutant exposure contributes to Black/White differences in leukocyte telomere length in the National Health and Nutrition Examination Survey
Roberts E, Boss J, Mukherjee B, Salerno S, Zota A, Needham B. Persistent organic pollutant exposure contributes to Black/White differences in leukocyte telomere length in the National Health and Nutrition Examination Survey. Scientific Reports 2022, 12: 19960. PMID: 36402910, PMCID: PMC9675834, DOI: 10.1038/s41598-022-24316-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultCross-Sectional StudiesEnvironmental PollutantsHumansLeukocytesNutrition SurveysPersistent Organic PollutantsPolychlorinated BiphenylsTelomereWhite PeopleConceptsNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyPersistent organic pollutantsLeukocyte telomere lengthNutrition Examination SurveyToxic equivalent quotientPolychlorinated biphenylsBlack/white differencesExamination SurveyCross-sectional National Health and Nutrition Examination SurveyNon-Hispanic Black AmericansExposure scoreNon-Hispanic white AmericansSurvey-weighted linear regression modelsIndirect effects of raceAssociated with longer leukocyte telomere lengthSingle-pollutant modelsIndividual persistent organic pollutantsExposure to polychlorinated biphenylsLonger leukocyte telomere lengthSelf-reported racePersistent organic pollutant exposuresBlack AmericansIndividual polychlorinated biphenylOrganic pollutant exposures
2019
High plasma concentrations of organic pollutants negatively impact survival in amyotrophic lateral sclerosis
Goutman S, Boss J, Patterson A, Mukherjee B, Batterman S, Feldman E. High plasma concentrations of organic pollutants negatively impact survival in amyotrophic lateral sclerosis. Journal Of Neurology Neurosurgery & Psychiatry 2019, 90: 907. PMID: 30760645, PMCID: PMC6625908, DOI: 10.1136/jnnp-2018-319785.Peer-Reviewed Original ResearchMeSH KeywordsAmyotrophic Lateral SclerosisEnvironmental ExposureEnvironmental PollutantsFemaleHalogenated Diphenyl EthersHumansMaleMiddle AgedPolychlorinated BiphenylsSurvivalConceptsPersistent organic pollutantsPolychlorinated biphenylsHigh concentrations of persistent organic pollutantsAmyotrophic lateral sclerosisConcentrations of persistent organic pollutantsEffects of persistent organic pollutantsMeasurement of persistent organic pollutantsHazard rate of mortalitySymptom onset to diagnosisMedian diagnostic ageNegatively impacts survivalLowest quartileIndependent of ageOrganic pollutantsSummary measuresMedian timeClinical featuresMedical recordsRate of mortalityDiagnostic ageEnvironmental exposuresBulbar onsetALS diseaseCervical onsetPlasma concentrations