2018
Associations between mixtures of urinary phthalate metabolites with gestational age at delivery: a time to event analysis using summative phthalate risk scores
Boss J, Zhai J, Aung M, Ferguson K, Johns L, McElrath T, Meeker J, Mukherjee B. Associations between mixtures of urinary phthalate metabolites with gestational age at delivery: a time to event analysis using summative phthalate risk scores. Environmental Health 2018, 17: 56. PMID: 29925380, PMCID: PMC6011420, DOI: 10.1186/s12940-018-0400-3.Peer-Reviewed Original ResearchConceptsMono-2-ethyl-5-carboxypentyl phthalateEnvironmental risk scoreGestational ageHazard ratioPreterm birthRisk scoreInterquartile rangeIncreased odds of preterm birthCases of preterm birthOdds of preterm birthUrinary phthalate metabolite concentrationsPhthalate metabolite concentrationsUrinary phthalate metabolitesPhthalate metabolite measurementsCox proportional hazards modelsInterquartile range changeTime to deliveryProportional hazards modelLongitudinal birth cohortSingle-pollutant analysesSignificant public health concernUrinary metabolite concentrationsBackgroundPreterm birthPregnant womenExposure to phthalates
2015
Associations between Maternal Biomarkers of Phthalate Exposure and Inflammation Using Repeated Measurements across Pregnancy
Ferguson K, McElrath T, Mukherjee B, Loch-Caruso R, Meeker J. Associations between Maternal Biomarkers of Phthalate Exposure and Inflammation Using Repeated Measurements across Pregnancy. PLOS ONE 2015, 10: e0135601. PMID: 26317519, PMCID: PMC4552851, DOI: 10.1371/journal.pone.0135601.Peer-Reviewed Original ResearchConceptsC-reactive proteinPregnant womenPhthalate exposureInvestigate inflammationInflammation biomarkersAnalysis of pregnant womenAssociated with adverse reproductive outcomesBiomarkers of phthalate exposureUrinary phthalate metabolitesAssociated with IL-6Plasma inflammation biomarkersMono-benzyl phthalateAdverse reproductive outcomesStatistically significant associationUrinary metabolite concentrationsMaternal biomarkersPeripheral inflammationPhthalate effectsPhthalate metabolitesIL-6Reproductive outcomesInflammationMono-benzylSignificant associationTarget tissues