2019
Association Between Life Purpose and Mortality Among US Adults Older Than 50 Years
Alimujiang A, Wiensch A, Boss J, Fleischer N, Mondul A, McLean K, Mukherjee B, Pearce C. Association Between Life Purpose and Mortality Among US Adults Older Than 50 Years. JAMA Network Open 2019, 2: e194270. PMID: 31125099, PMCID: PMC6632139, DOI: 10.1001/jamanetworkopen.2019.4270.Peer-Reviewed Original ResearchConceptsHealth and Retirement StudyCause-specific mortalityAll-causeHealth outcomesUS adultsHealth and Retirement Study participantsCohort study of US adultsCause-specific mortality analysesInterview periodStudy of US adultsInfluence health outcomesAssociated with all-cause mortalityLife purposeCohort study sampleWeighted Cox proportional hazards modelsNational cohort studyPurpose in lifeQuality of lifeAll-cause mortalityCox proportional hazards modelsEnhance overall qualityAssociated with decreased mortalityProportional hazards modelRetirement StudyMortality associations
2017
Neighborhood characteristics influence DNA methylation of genes involved in stress response and inflammation: The Multi-Ethnic Study of Atherosclerosis
Smith J, Zhao W, Wang X, Ratliff S, Mukherjee B, Kardia S, Liu Y, Roux A, Needham B. Neighborhood characteristics influence DNA methylation of genes involved in stress response and inflammation: The Multi-Ethnic Study of Atherosclerosis. Epigenetics 2017, 12: 662-673. PMID: 28678593, PMCID: PMC5687339, DOI: 10.1080/15592294.2017.1341026.Peer-Reviewed Original ResearchConceptsMulti-Ethnic Study of AtherosclerosisMulti-Ethnic StudyStudy of AtherosclerosisSocioeconomic disadvantageIndividual-level socioeconomic factorsEtiology of health disparitiesAssociated with poor health outcomesPopulation-based sample of US adultsSocioeconomic factorsNeighborhood conditionsNeighborhood socioeconomic disadvantageSample of US adultsNeighborhood social environmentHigher socioeconomic disadvantagePoor health outcomesIndividual socioeconomic factorsPopulation-based sampleDimensions of neighborhood contextHealth disparitiesInfluence methylation levelsHealth outcomesUS adultsSocial environmentDisadvantaged neighborhoodsNeighborhood characteristics