2023
Per- and Polyfluoroalkyl Substances (PFAS) and Lipid Trajectories in Women 45–56 Years of Age: The Study of Women’s Health Across the Nation
Kang H, Ding N, Karvonen-Gutierrez C, Mukherjee B, Calafat A, Park S. Per- and Polyfluoroalkyl Substances (PFAS) and Lipid Trajectories in Women 45–56 Years of Age: The Study of Women’s Health Across the Nation. Environmental Health Perspectives 2023, 131: 087004. PMID: 37552133, PMCID: PMC10408595, DOI: 10.1289/ehp12351.Peer-Reviewed Original ResearchConceptsStudy of Women's HealthOdds ratioWomen's HealthMidlife womenConfidence intervalsFavorable blood lipid profileEstimate odds ratiosAdverse effects of PFASSerum PFAS concentrationsLatent class growth modelingLongitudinal trajectoriesAssociated with totalMenopausal transitionAssociated with trajectoriesLow-density lipoprotein (LDL) cholesterolHigh-density lipoprotein (HDL) cholesterolLipid trajectoriesAverage follow-upBlood total cholesterolBlood lipid profileTriglycerides trajectoriesEpidemiological studiesPositive associationBlood lipidsLDL cholesterolThe role of exposure to per- and polyfluoroalkyl substances in racial/ethnic disparities in hypertension: Results from the study of Women's health across the nation
Ding N, Karvonen-Gutierrez C, Zota A, Mukherjee B, Harlow S, Park S. The role of exposure to per- and polyfluoroalkyl substances in racial/ethnic disparities in hypertension: Results from the study of Women's health across the nation. Environmental Research 2023, 227: 115813. PMID: 37004857, PMCID: PMC10227830, DOI: 10.1016/j.envres.2023.115813.Peer-Reviewed Original ResearchStudy of Women's HealthRacial/ethnic disparitiesWomen's HealthIncident hypertensionMidlife womenSerum PFAS concentrationsHypertension onsetModifiable risk factorsAnnual follow-up visitsCausal mediation analysisContribution of environmental pollutionPublic health problemAssociated with hypertensionRacial/ethnic differencesPFAS exposureBlack participantsWhite participantsFollow-up visitG-computationQuantile-based g-computationWhite womenHealth problemsPFAS concentrationsExposure to per-Disparities
2021
Per- and Polyfluoroalkyl Substances and Hormone Levels During the Menopausal Transition
Harlow S, Hood M, Ding N, Mukherjee B, Calafat A, Randolph J, Gold E, Park S. Per- and Polyfluoroalkyl Substances and Hormone Levels During the Menopausal Transition. The Journal Of Clinical Endocrinology & Metabolism 2021, 106: e4427-e4437. PMID: 34181018, PMCID: PMC8677593, DOI: 10.1210/clinem/dgab476.Peer-Reviewed Original ResearchConceptsMidlife womenSex hormone-binding globulinFollicle-stimulating hormoneInverse associationStudy of Women's HealthPositive associationMenopausal transitionBody mass indexReproductive ageWomen's HealthSignificant linear trendNo significant associationNulliparous womenLinear mixed modelsSmoking statusYears of ageMass indexHormone-binding globulinMenopausal statusLongitudinal serum concentrationsSignificant associationSerum PFAS concentrationsMidlifeWomenPolyfluoroalkyl substances
2019
Longitudinal trends in perfluoroalkyl and polyfluoroalkyl substances among multiethnic midlife women from 1999 to 2011: The Study of Women′s Health Across the Nation
Ding N, Harlow S, Batterman S, Mukherjee B, Park S. Longitudinal trends in perfluoroalkyl and polyfluoroalkyl substances among multiethnic midlife women from 1999 to 2011: The Study of Women′s Health Across the Nation. Environment International 2019, 135: 105381. PMID: 31841808, PMCID: PMC7374929, DOI: 10.1016/j.envint.2019.105381.Peer-Reviewed Original ResearchConceptsMidlife womenWomen's HealthBlack womenStudy of Women's HealthChinese womenLongitudinal trendsTemporal trendsBody mass indexSerum concentrationsLinear mixed modelsParous womenFollow-up visitPFAS homologuesPFNA concentrationsRace/ethnicityMass indexSerum PFAS concentrationsMidlifePatterns of exposurePolyfluoroalkyl substances concentrationsLongitudinal declineWomenAssociated with lower concentrationsHealthMixed models