2022
Exposure to heavy metals and hormone levels in midlife women: The Study of Women's Health Across the Nation (SWAN)
Wang X, Ding N, Harlow S, Randolph J, Mukherjee B, Gold E, Park S. Exposure to heavy metals and hormone levels in midlife women: The Study of Women's Health Across the Nation (SWAN). Environmental Pollution 2022, 317: 120740. PMID: 36436662, PMCID: PMC9897061, DOI: 10.1016/j.envpol.2022.120740.Peer-Reviewed Original ResearchConceptsUrinary metal concentrationsExposure to heavy metalsHeavy metalsMetal concentrationsStudy of Women's HealthAssociation of heavy metalsEnvironmental heavy metal exposureHeavy metal exposureSex hormone-binding globulinFollicle-stimulating hormoneWomen's HealthBayesian kernel machine regressionAssociated with E<sub>2</sub>, TMidlife womenKernel machine regressionMetal exposureSerum hormone levelsMetal mixturesHealth-related factorsNation Multi-Pollutant StudyCalculate percent changesCadmiumHormone levelsProspective cohort studyLinear mixed effects modelsPer- and polyfluoroalkyl substances and incident diabetes in midlife women: the Study of Women’s Health Across the Nation (SWAN)
Park S, Wang X, Ding N, Karvonen-Gutierrez C, Calafat A, Herman W, Mukherjee B, Harlow S. Per- and polyfluoroalkyl substances and incident diabetes in midlife women: the Study of Women’s Health Across the Nation (SWAN). Diabetologia 2022, 65: 1157-1168. PMID: 35399113, PMCID: PMC9177697, DOI: 10.1007/s00125-022-05695-5.Peer-Reviewed Original ResearchConceptsStudy of Women's HealthIncident diabetesWomen's HealthPolyfluoroalkyl substancesDiabetes riskMidlife womenSelf-reported diabetesTotal energy intakeProspective cohort studyIncreased diabetes riskCox proportional hazards modelsPhysical activityGlucose-lowering medicationsProportional hazards modelResultsAfter adjustmentNation Multi-Pollutant StudyBottom tertileSmoking statusHighest tertileAlcohol consumptionDiabetes-free womenFollow-up visitG-computationQuantile-based g-computationCohort study
2021
Urinary concentrations of phenols and parabens and incident diabetes in midlife women
Lee S, Karvonen-Gutierrez C, Mukherjee B, Herman W, Harlow S, Park S. Urinary concentrations of phenols and parabens and incident diabetes in midlife women. Environmental Epidemiology 2021, 5: e171. PMID: 34934892, PMCID: PMC8683147, DOI: 10.1097/ee9.0000000000000171.Peer-Reviewed Original ResearchIncident diabetesHazard ratioAssociated with incident diabetesStudy of Women's HealthMid-life womenAdjusted hazard ratiosAssociation of incident diabetesProspective cohort studyWomen's HealthNo significant associationWomen's backgroundConcentration of phenolJoint effectsExposure variablesG-computationQuantile-based g-computationWithin-person variabilityBenzophenone-3Cohort studyDiabetes-freeBisphenol ANonlinear associationSignificant associationJoint effect of mixturesConcentrations of bisphenol A
2019
Multicenter Prospective Cohort Study of the Diagnostic Yield and Patient Experience of Multiplex Gene Panel Testing For Hereditary Cancer Risk
Idos G, Kurian A, Ricker C, Sturgeon D, Culver J, Kingham K, Koff R, Chun N, Rowe-Teeter C, Lebensohn A, Levonian P, Lowstuter K, Partynski K, Hong C, Mills M, Petrovchich I, S. C, Hartman A, Allen B, Wenstrup R, Lancaster J, Brown K, Kidd J, Evans B, Mukherjee B, McDonnell K, Ladabaum U, Ford J, Gruber S. Multicenter Prospective Cohort Study of the Diagnostic Yield and Patient Experience of Multiplex Gene Panel Testing For Hereditary Cancer Risk. JCO Precision Oncology 2019, 3: po.18.00217. PMID: 34322651, PMCID: PMC8260917, DOI: 10.1200/po.18.00217.Peer-Reviewed Original ResearchMultiplex gene panel testProspective cohort studyGene panel testingPatient experiencePathogenic variantsDiagnostic yieldCohort studyNorris Comprehensive Cancer CenterHereditary cancer riskSocioeconomically diverse cohortComprehensive cancer centerPost-test surveysPanel testingCancer susceptibility genesMulticenter prospective cohort studyLos Angeles CountyUniversity of Southern California Medical CenterIdentified pathogenic variantsCancer riskSouthern California Medical CenterLess educationPatient regretProphylactic surgeryExpert clinical assessmentCalifornia Medical Center
2014
Urinary Phthalate Metabolite Associations with Biomarkers of Inflammation and Oxidative Stress Across Pregnancy in Puerto Rico
Ferguson K, Cantonwine D, Rivera-González L, Loch-Caruso R, Mukherjee B, Del Toro L, Jiménez-Vélez B, Calafat A, Ye X, Alshawabkeh A, Cordero J, Meeker J. Urinary Phthalate Metabolite Associations with Biomarkers of Inflammation and Oxidative Stress Across Pregnancy in Puerto Rico. Environmental Science And Technology 2014, 48: 7018-7025. PMID: 24845688, PMCID: PMC4066910, DOI: 10.1021/es502076j.Peer-Reviewed Original ResearchConceptsMono-n-butyl phthalateBiomarkers of inflammationIL-10Prospective cohort study of pregnant womenDi-2-ethylhexyl phthalate metabolitesCohort study of pregnant womenIL-6Study of pregnant womenAssociated with increased IL-6Oxidative stressUrinary phthalate metabolitesC-reactive proteinProspective cohort studyAdverse birth outcomesMetabolites of di-2-ethylhexyl phthalateOxidative stress markersPreterm birthMetabolite associationsPregnant womenMono-n-butylDi-2-ethylhexyl phthalateOxidative stress biomarkersBirth outcomesTNF-aInflammation biomarkers
2012
Air-Pollution and Cardiometabolic Diseases (AIRCMD): A prospective study investigating the impact of air pollution exposure and propensity for type II diabetes
Sun Z, Mukherjee B, Brook R, Gatts G, Yang F, Sun Q, Brook J, Fan Z, Rajagopalan S. Air-Pollution and Cardiometabolic Diseases (AIRCMD): A prospective study investigating the impact of air pollution exposure and propensity for type II diabetes. The Science Of The Total Environment 2012, 448: 72-78. PMID: 23182147, PMCID: PMC4548977, DOI: 10.1016/j.scitotenv.2012.10.087.Peer-Reviewed Original ResearchConceptsAir pollution exposureAir pollutionAmbient fine particulate matterMeasures of air pollution exposureImpact of air pollution exposureFine particulate matterExposure to PM2.5Air pollution measurementsPersonal exposure measurementsCreation of novel methodologiesSub-acute exposurePolluted urban environmentsImpact of environmental factorsParticulate matterPollution exposureStudy visitsPollution measurementsType II diabetesProspective cohort studyEnvironmental risk factorsAmbient measurementsII diabetesCohort studyUrban environmentScreening visit