2023
A Synthetic Data Integration Framework to Leverage External Summary-Level Information from Heterogeneous Populations
Gu T, Taylor J, Mukherjee B. A Synthetic Data Integration Framework to Leverage External Summary-Level Information from Heterogeneous Populations. Biometrics 2023, 79: 3831-3845. PMID: 36876883, PMCID: PMC10480346, DOI: 10.1111/biom.13852.Peer-Reviewed Original ResearchConceptsCovariate effectsStatistical inferenceHeterogeneity of covariate effectsRegression coefficient estimatesSummary-level informationImprove statistical inferenceInternational studiesOutcome YCovariate informationData integration frameworkStatistical efficiencyCoefficient estimatesPartial informationExternal populationGeneral frameworkIndividual-level dataRisk prediction modelExternal modelPrediction problemInternational study populationMultiple imputation
2012
Incorporating auxiliary information for improved prediction in high-dimensional datasets: an ensemble of shrinkage approaches
Boonstra P, Taylor J, Mukherjee B. Incorporating auxiliary information for improved prediction in high-dimensional datasets: an ensemble of shrinkage approaches. Biostatistics 2012, 14: 259-272. PMID: 23087411, PMCID: PMC3590922, DOI: 10.1093/biostatistics/kxs036.Peer-Reviewed Original ResearchConceptsHigh-dimensional datasetsAuxiliary informationRidge estimatorBayesian alternativeOutcome YSimulation studyEstimates of BShrinkage approachBiological processesRidge regressionGene expression datasetsDatasetGenomic technologiesMicroarray technologyOptimal choiceBalance efficiencyX.EstimationPrediction errorPolymerase chain reactionBiological phenomenaInformationTechnologyQuantitative real-time polymerase chain reaction