2023
Associations Between Repeated Measures of Urinary Phthalate Metabolites With Hormones and Timing of Natural Menopause
Ding N, Zheutlin E, Harlow S, Randolph J, Mukherjee B, Park S. Associations Between Repeated Measures of Urinary Phthalate Metabolites With Hormones and Timing of Natural Menopause. Journal Of The Endocrine Society 2023, 7: bvad024. PMID: 36846211, PMCID: PMC9945847, DOI: 10.1210/jendso/bvad024.Peer-Reviewed Original ResearchSex hormone-binding globulinFollicle-stimulating hormoneAnti-Mullerian hormoneUrinary phthalate metabolitesTiming of natural menopausePhthalate metabolitesNatural menopauseExposure to phthalatesMeasures of urinary phthalate metabolitesAssociations of phthalate metabolitesHazard ratioAssociations of urinary phthalate metabolitesSerum concentrations of estradiolHormone-binding globulinCox proportional-hazards modelStudy of Women's HealthConcentrations of estradiolCalculate hazard ratiosProportional-hazards modelStatistically significant associationCirculating levels of testosteroneLevels of testosteroneHormone therapyOvarian reserveMidlife women
2022
Associations between Repeated Measures of Urinary Phthalate Metabolites with Hormones and Timing of Natural Menopause: The Study of Women's Health Across the Nation
Ding N, Zheutlin E, Harlow S, Randolph J, Mukherjee B, Park S. Associations between Repeated Measures of Urinary Phthalate Metabolites with Hormones and Timing of Natural Menopause: The Study of Women's Health Across the Nation. ISEE Conference Abstracts 2022, 2022 DOI: 10.1289/isee.2022.p-1181.Peer-Reviewed Original ResearchPerfluoroalkyl Substances and Incident Natural Menopause in Midlife Women: The Mediating Role of Sex Hormones
Ding N, Harlow S, Randolph J, Mukherjee B, Batterman S, Gold E, Park S. Perfluoroalkyl Substances and Incident Natural Menopause in Midlife Women: The Mediating Role of Sex Hormones. American Journal Of Epidemiology 2022, 191: 1212-1223. PMID: 35292812, PMCID: PMC9393069, DOI: 10.1093/aje/kwac052.Peer-Reviewed Original Research
2021
Urinary metals and metal mixtures and timing of natural menopause in midlife women: The Study of Women’s Health Across the Nation
Wang X, Ding N, Harlow S, Randolph J, Mukherjee B, Gold E, Park S. Urinary metals and metal mixtures and timing of natural menopause in midlife women: The Study of Women’s Health Across the Nation. Environment International 2021, 157: 106781. PMID: 34311223, PMCID: PMC8490279, DOI: 10.1016/j.envint.2021.106781.Peer-Reviewed Original ResearchConceptsMetal mixturesMetal concentrationsTiming of natural menopauseCox proportional hazards modelsNatural menopauseStudy of Women's HealthProportional hazards modelHazard ratioEnvironmental risk scoreLowest quartileIndividual metal concentrationsExposure to metalsUrinary metal concentrationsHazards modelMedian follow-upMonths of amenorrheaWomen's HealthAssociated with earlier natural menopauseEarly natural menopauseUrinary metalsNation Multi-Pollutant StudyBleeding episodesHormone therapyPremenopausal womenMedian age
2020
Associations of Perfluoroalkyl Substances with Incident Natural Menopause: The Study of Women’s Health Across the Nation
Ding N, Harlow S, Randolph J, Calafat A, Mukherjee B, Batterman S, Gold E, Park S. Associations of Perfluoroalkyl Substances with Incident Natural Menopause: The Study of Women’s Health Across the Nation. The Journal Of Clinical Endocrinology & Metabolism 2020, 105: dgaa303. PMID: 32491182, PMCID: PMC7418447, DOI: 10.1210/clinem/dgaa303.Peer-Reviewed Original ResearchConceptsStudy of Women's HealthNatural menopauseHazard ratioSerum concentrationsWomen's HealthCohort of midlife womenConfidence intervalsCalculate hazard ratiosAdverse health outcomesPFAS serum concentrationsMonths of amenorrheaAssociation of perfluoroalkyl substancesEarly natural menopauseBaseline serum concentrationsCox proportional hazards modelsAssociated with earlier natural menopauseIsotope dilution tandem mass spectrometryHealth outcomesProportional hazards modelReverse causationBleeding episodesMidlife womenLowest tertileMedian timeHormone use