2021
Cross-Sectional Estimation of Endogenous Biomarker Associations with Prenatal Phenols, Phthalates, Metals, and Polycyclic Aromatic Hydrocarbons in Single-Pollutant and Mixtures Analysis Approaches
Aung M, Yu Y, Ferguson K, Cantonwine D, Zeng L, McElrath T, Pennathur S, Mukherjee B, Meeker J. Cross-Sectional Estimation of Endogenous Biomarker Associations with Prenatal Phenols, Phthalates, Metals, and Polycyclic Aromatic Hydrocarbons in Single-Pollutant and Mixtures Analysis Approaches. Environmental Health Perspectives 2021, 129: 037007. PMID: 33761273, PMCID: PMC7990518, DOI: 10.1289/ehp7396.Peer-Reviewed Original ResearchConceptsExposure analytesToxicity classesMixtures of toxicantsSingle-pollutant modelsPolycyclic aromatic hydrocarbonsHierarchical Bayesian kernel machine regressionBayesian kernel machine regressionKernel machine regressionPrenatal toxicant exposureAdaptive elastic net regressionClasses of toxicantsSingle-pollutantTrace metalsAromatic hydrocarbonsToxic mixturePair-wise associationsAdaptive elastic netToxicant exposurePhthalateMachine regressionEndogenous biomarkersBiomarkers indicativeMultiple linear regressionMetalToxicity
2020
Urinary metals and adipokines in midlife women: The Study of Women's Health Across the nation (SWAN)
Wang X, Karvonen-Gutierrez C, Mukherjee B, Herman W, Park S. Urinary metals and adipokines in midlife women: The Study of Women's Health Across the nation (SWAN). Environmental Research 2020, 196: 110426. PMID: 33157106, PMCID: PMC8093324, DOI: 10.1016/j.envres.2020.110426.Peer-Reviewed Original ResearchConceptsStudy of Women's HealthWomen's HealthExposure to cadmiumUrinary metal concentrationsUrinary molybdenumMetal concentrationsMetal exposureSOB-RUrinary metalsNation Multi-Pollutant StudyAssociated with favorable profilesStandard deviation increaseCadmiumLinear regression modelsAdverse adipokine profileMidlife womenLevels of sOB-RHMW adiponectinUrinary cesiumFollow-up visitHuman populationSoluble leptin receptorAdaptive elastic-netSOB-R levelsMetalPredictors of urinary and blood Metal(loid) concentrations among pregnant women in Northern Puerto Rico
Ashrap P, Watkins D, Mukherjee B, Boss J, Richards M, Rosario Z, Vélez-Vega C, Alshawabkeh A, Cordero J, Meeker J. Predictors of urinary and blood Metal(loid) concentrations among pregnant women in Northern Puerto Rico. Environmental Research 2020, 183: 109178. PMID: 32007748, PMCID: PMC7167342, DOI: 10.1016/j.envres.2020.109178.Peer-Reviewed Original ResearchConceptsBlood concentrations of CuTrace metal exposureConcentrations of CuExposure reduction strategiesBiomarkers of exposureBlood HgMetalloid exposureMetal exposureNorthern Puerto RicoBlood CdTrace metalsBlood PbRice consumptionExposure sourcesPuerto RicoMetal(loid)sMetal(loidExposure assessmentBiomarker variationsPbPublic waterZnFishMnMetal
2019
Urinary metals and metal mixtures in midlife women: The Study of Women's Health Across the Nation (SWAN)
Wang X, Mukherjee B, Batterman S, Harlow S, Park S. Urinary metals and metal mixtures in midlife women: The Study of Women's Health Across the Nation (SWAN). International Journal Of Hygiene And Environmental Health 2019, 222: 778-789. PMID: 31103473, PMCID: PMC6583796, DOI: 10.1016/j.ijheh.2019.05.002.Peer-Reviewed Original ResearchConceptsMultiple metalsMetal mixturesExposure to multiple metalsExposure patternsConcentrations of metalsExposure to metalsConsumption of seafoodHigh-resolution inductively coupled plasma mass spectrometryInductively coupled plasma mass spectrometryMeasured urinary concentrationsGeometric mean concentrationsMetal exposurePlasma mass spectrometrySeafood intakeUrinary metalsMean concentrationsRice intakeSeafoodUrinary concentrationsDetectable concentrationHigher exposuresGeographical characteristicsMercuryLead levelsMetal