2024
Associations of urinary polycyclic aromatic hydrocarbon (PAH) metabolites and their mixture with thyroid hormone concentration during pregnancy:A repeated measures study
Park S, Siwakoti R, Ferguson K, Cathey A, Hao W, Cantonwine D, Mukherjee B, Mcelrath T, Meeker J. Associations of urinary polycyclic aromatic hydrocarbon (PAH) metabolites and their mixture with thyroid hormone concentration during pregnancy:A repeated measures study. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.0311.Peer-Reviewed Original ResearchAssociations of urinary polycyclic aromatic hydrocarbon (PAH) metabolites and their mixture with thyroid hormone concentration during pregnancy in the LIFECODES cohort: A repeated measures study
Park S, Siwakoti R, Ferguson K, Cathey A, Hao W, Cantonwine D, Mukherjee B, McElrath T, Meeker J. Associations of urinary polycyclic aromatic hydrocarbon (PAH) metabolites and their mixture with thyroid hormone concentration during pregnancy in the LIFECODES cohort: A repeated measures study. Environmental Research 2024, 255: 119205. PMID: 38782334, PMCID: PMC11421857, DOI: 10.1016/j.envres.2024.119205.Peer-Reviewed Original ResearchMaternal thyroid hormonesThyroid hormone concentrationsPolycyclic aromatic hydrocarbon metabolitesThyroid hormonesPolycyclic aromatic hydrocarbonsPregnancy outcomesHormone concentrationsFetal sex-specific effectsPAH exposureBayesian kernel machine regressionPotential non-linear associationsHormone physiologyAromatic hydrocarbonsThyroid hormone physiologyPregnancy physiologyFetal growthFetal sexFetal developmentUrinary PAH metabolitesSerial measurementsPregnancyUrinary polycyclic aromatic hydrocarbonsPolycyclic aromatic hydrocarbon exposureStudy visitsThyroid
2022
Mediation by hormone concentrations on the associations between repeated measures of phthalate mixture exposure and timing of delivery
Cathey A, Aung M, Watkins D, Rosario Z, Vélez Vega C, Alshawabkeh A, Cordero J, Mukherjee B, Meeker J. Mediation by hormone concentrations on the associations between repeated measures of phthalate mixture exposure and timing of delivery. Journal Of Exposure Science & Environmental Epidemiology 2022, 32: 374-383. PMID: 34987188, PMCID: PMC9124667, DOI: 10.1038/s41370-021-00408-3.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthPreterm birthCorticotropin-releasing hormoneFetal sexMale fetusesEarly deliveryHormone concentrationsAssociated with earlier deliveryPhthalate exposurePhthalate mixtureReduced gestational ageTime of deliveryEnvironmental risk scoreGestational ageFemale fetusesUrinary phthalatesSex-specific analysesEndocrine-disrupting capabilitiesReleasing hormoneSerum hormonesFetusesRisk scoreSusceptible to endocrine disruptionBirth cohortHormone
2021
Gestational Hormone Concentrations Are Associated With Timing of Delivery in a Fetal Sex-Dependent Manner
Cathey A, Watkins D, Rosario Z, Vega C, Mukherjee B, O’Neill M, Loch-Caruso R, Alshawabkeh A, Cordero J, Meeker J. Gestational Hormone Concentrations Are Associated With Timing of Delivery in a Fetal Sex-Dependent Manner. Frontiers In Endocrinology 2021, 12: 742145. PMID: 34603214, PMCID: PMC8479114, DOI: 10.3389/fendo.2021.742145.Peer-Reviewed Original ResearchConceptsTime of deliveryFetal sexBody mass indexGestational ageMaternal agePreterm premature rupture of membranesPre-pregnancy body mass indexHormone concentrationsFetal sex-specific effectsPremature rupture of membranesOverall preterm birthPreterm premature ruptureSpontaneous preterm laborRupture of membranesReduced gestational ageOdds of PTBTime of laborSignificant public health problemTobacco smoke exposureGestational hormonesSpontaneous PTBPreterm laborWeeks gestationPreterm birthLongitudinal birth cohortHormone concentrations mediate the associations between exposure to phthalate mixtures and preterm birth
Cathey A, Aung M, Watkins D, Rosario Z, Vélez Vega C, Alshawabkeh A, Cordero J, Mukherjee B, Meeker J. Hormone concentrations mediate the associations between exposure to phthalate mixtures and preterm birth. ISEE Conference Abstracts 2021, 2021 DOI: 10.1289/isee.2021.p-299.Peer-Reviewed Original Research
2018
Associations between maternal phenol and paraben urinary biomarkers and maternal hormones during pregnancy: A repeated measures study
Aker A, Johns L, McElrath T, Cantonwine D, Mukherjee B, Meeker J. Associations between maternal phenol and paraben urinary biomarkers and maternal hormones during pregnancy: A repeated measures study. Environment International 2018, 113: 341-349. PMID: 29366524, PMCID: PMC5866216, DOI: 10.1016/j.envint.2018.01.006.Peer-Reviewed Original ResearchConceptsThyroid hormonesAssociated with altered thyroid hormone levelsFetal health outcomesThyroid hormone levelsIQR increaseMultivariate regression analysisGestational ageMultivariate linear regression modelFetal neurodevelopmentPregnant womenFree thyroxinePotential biological mechanismsTime of exposureUrinary biomarkersCohort studyHormone levelsParaben biomarkersTotal triiodothyronineCase-control samplePregnancyBlood samplesTotal thyroxineHormone concentrationsHealth outcomesHormone