2019
Bayesian Shrinkage Estimation of High Dimensional Causal Mediation Effects in Omics Studies
Song Y, Zhou X, Zhang M, Zhao W, Liu Y, Kardia S, Roux A, Needham B, Smith J, Mukherjee B. Bayesian Shrinkage Estimation of High Dimensional Causal Mediation Effects in Omics Studies. Biometrics 2019, 76: 700-710. PMID: 31733066, PMCID: PMC7228845, DOI: 10.1111/biom.13189.Peer-Reviewed Original ResearchConceptsMediation analysisEffect of socioeconomic statusPotential mediatorsMulti-Ethnic StudyCausal mediation analysisCardiometabolic outcomesDNA methylation regionsSocioeconomic statusHigh-throughput technologiesMediation effectGenomic dataEpidemiological dataMethylation regionsHigh-dimensional mediatorsBayesian inference methodsContinuous shrinkage priorsHigh-dimensional settingsBayesian shrinkage estimatorsJoint analysisOutcomesShrinkage priorsPathwayNull caseInference methodsBiomedical studies
2011
Logistic regression analysis of biomarker data subject to pooling and dichotomization
Zhang Z, Liu A, Lyles R, Mukherjee B. Logistic regression analysis of biomarker data subject to pooling and dichotomization. Statistics In Medicine 2011, 31: 2473-2484. PMID: 21953741, DOI: 10.1002/sim.4367.Peer-Reviewed Original ResearchConceptsPopulation-based case-control study of colorectal cancerCase-control study of colorectal cancerProspective logistic regression modelPopulation-based case-control studyStudy of colorectal cancerEpidemiological studiesLogistic regression modelsAnalysis of epidemiological dataLogistic regression analysisBinary exposurePooled measureColorectal cancerRegression modelsEpidemiological dataRegression analysisAnalysis of biomarker dataDisease statusExposed subjectsBiomarker dataChoice of designSubjectsEstimated parametersStatusRecommendations