2014
No effect of acute exposure to coarse particulate matter air pollution in a rural location on high-density lipoprotein function
Maiseyeu A, Yang H, Ramanathan G, Yin F, Bard R, Morishita M, Dvonch J, Wang L, Spino C, Mukherjee B, Badgeley M, Barajas-Espinosa A, Sun Q, Harkema J, Rajagopalan S, Araujo J, Brook R. No effect of acute exposure to coarse particulate matter air pollution in a rural location on high-density lipoprotein function. Inhalation Toxicology 2014, 26: 23-29. PMID: 24417404, PMCID: PMC4445365, DOI: 10.3109/08958378.2013.850761.Peer-Reviewed Original ResearchConceptsRural locationsParticulate matter air pollutionHDL dysfunctionHDL anti-oxidative capacityRandomized double-blind crossover studyDouble-blind crossover studyHDL functionHDL-mediated cholesterol efflux capacityParaoxonase activityFiltered airVascular protective functionCholesterol efflux capacityHigh-density lipoprotein (HDL) particlesMetrics of HDL functionHDL-mediated effluxConcentrated ambient particlesCrossover studyImpact of PMEfflux capacityPM exposureVenous bloodAnimal studiesHealthy humansCoarse PMWilcoxon test
2010
Hemoglobin, Lead Exposure, and Intelligence Quotient: Effect Modification by the DRD2 Taq IA Polymorphism
Roy A, Hu H, Bellinger D, Mukherjee B, Modali R, Nasaruddin K, Schwartz J, Wright R, Ettinger A, Palaniapan K, Balakrishnan K. Hemoglobin, Lead Exposure, and Intelligence Quotient: Effect Modification by the DRD2 Taq IA Polymorphism. Environmental Health Perspectives 2010, 119: 144-149. PMID: 21205584, PMCID: PMC3018494, DOI: 10.1289/ehp.0901878.Peer-Reviewed Original ResearchConceptsDRD2 Taq IA polymorphismIntelligence quotientIQ pointsAssociated with higher IQDopamine D2 receptorsScale of IntelligenceProtective effect of hemoglobinLog blood leadD2 receptorsDRD2 polymorphismsHigher IQDRD2IA categoriesLead exposureCognitionGeneralized estimating equationsSignificant public health issueChildrenIntelligenceEffects of leadAnimal studiesChildren 3DopamineMassARRAY iPLEX platformHigher hemoglobin levels