Merit of quinacrine in the decrease of ingested sulfite-induced toxic action in rat brain
Kencebay C, Derin N, Ozsoy O, Kipmen-Korgun D, Tanriover G, Ozturk N, Basaranlar G, Yargicoglu-Akkiraz P, Sozen B, Agar A. Merit of quinacrine in the decrease of ingested sulfite-induced toxic action in rat brain. Food And Chemical Toxicology 2012, 52: 129-136. PMID: 23168241, DOI: 10.1016/j.fct.2012.11.015.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApoptosisBrainCaspase 3Evoked PotentialsLipid PeroxidationMalePhospholipases A2, SecretoryQuinacrineRatsRats, WistarSulfitesSulfonic AcidsThiobarbituric Acid Reactive SubstancesConceptsSomatosensory evoked potentialsSecretory phospholipase A2Quinacrine administrationS groupPlasma-S-sulfonate levelLatencies of SEP componentsMale albino Wistar ratsBrain TBARS levelsControl levelsTUNEL-positive cellsSQ groupTBARS levelsAlbino Wistar ratsSPLA2 levelsApoptotic cell deathGastric gavageSEP alterationsPositive cellsWistar ratsSEP componentsIntraperitoneal injectionRat brainCaspase-3RatsQuinacrine treatment