2009
The Semmes Weinstein monofilament examination as a screening tool for diabetic peripheral neuropathy
Feng Y, Schlösser FJ, Sumpio BE. The Semmes Weinstein monofilament examination as a screening tool for diabetic peripheral neuropathy. Journal Of Vascular Surgery 2009, 50: 675-682.e1. PMID: 19595541, DOI: 10.1016/j.jvs.2009.05.017.Peer-Reviewed Original ResearchMeSH KeywordsDiabetic NeuropathiesEarly DiagnosisEvidence-Based MedicineFootHumansMass ScreeningNeural ConductionNeurologic ExaminationPredictive Value of TestsSensitivity and SpecificityTouchConceptsSemmes-Weinstein monofilament examinationDiabetic peripheral neuropathyNerve conduction studiesNegative predictive valuePositive predictive valueDiagnostic valueMonofilament examinationPeripheral neuropathyDiabetes mellitusPredictive valueLower extremity amputationRisk of ulcerationPublication date restrictionsCurrent literatureReference testConduction studiesExtremity amputationPlantar aspectDate restrictionsCurrent evidenceFifth metatarsalGreat toePubMed databaseEarly interventionIndependent investigators
2005
Sustained orbital shear stress stimulates smooth muscle cell proliferation via the extracellular signal-regulated protein kinase 1/2 pathway
Asada H, Paszkowiak J, Teso D, Alvi K, Thorisson A, Frattini JC, Kudo FA, Sumpio BE, Dardik A. Sustained orbital shear stress stimulates smooth muscle cell proliferation via the extracellular signal-regulated protein kinase 1/2 pathway. Journal Of Vascular Surgery 2005, 42: 772-780. PMID: 16242567, DOI: 10.1016/j.jvs.2005.05.046.Peer-Reviewed Original ResearchConceptsOrbital shear stressPresence of PD98059Synthetic phenotypeERK1/2 pathwayExtracellular signal-regulated proteinSMC proliferationSmooth muscle cell proliferationMuscle cell proliferationPathway inhibitor PD98059Cell proliferationExtracellular signal-regulated protein kinase 1/2 (ERK1/2) phosphorylationKinase 1/2 phosphorylationPresence of SB203580Bovine SMCsSMC phenotypeInhibitor PD98059Inhibitor SB203580Contractile phenotypePD98059Long-term culturePhenotypeCell nuclear antigenExpression of markersPathwaySB203580