2003
Antisense basic fibroblast growth factor alters the time course of mitogen-activated protein kinase in arterialized vein graft remodeling
Yamashita A, Hanna AK, Hirata S, Dardik A, Sumpio BE. Antisense basic fibroblast growth factor alters the time course of mitogen-activated protein kinase in arterialized vein graft remodeling. Journal Of Vascular Surgery 2003, 37: 866-873. PMID: 12663990, DOI: 10.1067/mva.2003.130.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood Vessel ProsthesisCell Physiological PhenomenaEndothelium, VascularFibroblast Growth FactorsHyperplasiaJNK Mitogen-Activated Protein KinasesMitogen-Activated Protein KinasesModels, AnimalP38 Mitogen-Activated Protein KinasesProteinsRabbitsRegenerationRNA, AntisenseTime FactorsTransfectionVeinsConceptsProtein kinaseBasic fibroblast growth factorMAPK activationFibroblast growth factorMitogen-activated protein kinase (MAPK) familyC-Jun N-terminal protein kinaseProtein kinase familyExtracellular signal-regulated kinase 1/2Antisense basic fibroblast growth factorMitogen-activated protein kinaseSignal-regulated kinase 1/2Messenger RNA sequencesP38 kinase activationGrowth factor altersMAPK-dependent mechanismFibroblast growth factor activityGrowth factorKinase familyKinase activationGrowth factor activityPhosphorylation of MAPKsKinase 1/2RNA sequencesWestern blot analysisBasic fibroblast growth factor activity
1998
Mechanical Strain Rapidly Redistributes Tyrosine Phosphorylated Proteins in Human Intestinal Caco-2 Cells
Han O, Sumpio B, Basson M. Mechanical Strain Rapidly Redistributes Tyrosine Phosphorylated Proteins in Human Intestinal Caco-2 Cells. Biochemical And Biophysical Research Communications 1998, 250: 668-673. PMID: 9784404, DOI: 10.1006/bbrc.1998.9372.Peer-Reviewed Original ResearchConceptsCaco-2 cellsTyrosine kinase activityHuman intestinal Caco-2 cellsIntestinal Caco-2 cellsCaco-2 intestinal cellsRepetitive strainHuman Caco-2 intestinal cellsCaco-2 intestinal epithelial cellsIntestinal epithelial cellsHuman Caco-2 intestinal epithelial cellsKinase activityTyrosine phosphorylationIntestinal cellsEpithelial cellsModulates differentiationParticulate fractionTyrosine phosphorylated proteinsCellsSubcellular distribution
1997
Effect of strain on human keratinocytes in vitro
Takei T, Rivas‐Gotz C, Delling C, Koo J, Mills I, McCarthy T, Centrella M, Sumpio B. Effect of strain on human keratinocytes in vitro. Journal Of Cellular Physiology 1997, 173: 64-72. PMID: 9326450, DOI: 10.1002/(sici)1097-4652(199710)173:1<64::aid-jcp8>3.0.co;2-h.Peer-Reviewed Original Research
1988
Cyclosporine toxicity in the isolated perfused rat kidney.
Sumpio BE. Cyclosporine toxicity in the isolated perfused rat kidney. Transplantation Proceedings 1988, 20: 712-6. PMID: 3388509.Peer-Reviewed Original Research
1985
Renal handling of proteins in normal and disease states.
Sumpio B, Hayslett J. Renal handling of proteins in normal and disease states. QJM 1985, 57: 611-35. PMID: 4080952.Peer-Reviewed Original Research
1984
Kinetics of Renal Catabolism of Absorbed Proteins: Influence of Lysosomal pH
Camargo M, Sumpio B, Maack T. Kinetics of Renal Catabolism of Absorbed Proteins: Influence of Lysosomal pH. Contributions To Nephrology 1984, 42: 19-29. PMID: 6099789, DOI: 10.1159/000409957.Peer-Reviewed Original Research
1982
Kinetics, competition, and selectivity of tubular absorption of proteins
Sumpio BE, Maack T. Kinetics, competition, and selectivity of tubular absorption of proteins. American Journal Of Physiology 1982, 243: f379-f392. PMID: 7124951, DOI: 10.1152/ajprenal.1982.243.4.f379.Peer-Reviewed Original ResearchConceptsBeta 2MTubular absorptionHuman growth hormoneLow perfusate calcium concentrationsPerfusate calcium concentrationMorphologic damageTubular epitheliumProximal tubulesGrowth hormoneRat kidneyCationic proteinCalcium concentrationSaturable processSaturating loadSelective effectLuminal wallLow apparent affinityTubulesImportant determinantReversible mannerApparent affinityMicrovilliProteinKidney