2024
Assessment and mitigation of bias in influenza and COVID-19 vaccine effectiveness analyses — IVY Network, September 1, 2022–March 30, 2023
Lewis N, Harker E, Leis A, Zhu Y, Talbot H, Grijalva C, Halasa N, Chappell J, Johnson C, Rice T, Casey J, Lauring A, Gaglani M, Ghamande S, Columbus C, Steingrub J, Shapiro N, Duggal A, Felzer J, Prekker M, Peltan I, Brown S, Hager D, Gong M, Mohamed A, Exline M, Khan A, Wilson J, Mosier J, Qadir N, Chang S, Ginde A, Mohr N, Mallow C, Harris E, Johnson N, Srinivasan V, Gibbs K, Kwon J, Vaughn I, Ramesh M, Safdar B, DeCuir J, Surie D, Dawood F, Ellington S, Self W, Martin E. Assessment and mitigation of bias in influenza and COVID-19 vaccine effectiveness analyses — IVY Network, September 1, 2022–March 30, 2023. Vaccine 2024, 43: 126492. PMID: 39515195, DOI: 10.1016/j.vaccine.2024.126492.Peer-Reviewed Original ResearchCo-circulating virusesRespiratory syncytial virusCOVID-19-associated hospitalizationVaccine effectivenessControl groupRespiratory pathogensInfluenza-associated hospitalizationsExclusion of patientsStudies of vaccine effectivenessAcute respiratory illnessTest-negative studySentinel Surveillance NetworkEstimates of VEInfluenza VEInfluenza-associatedVE controlsReal-world analysisSyncytial virusVE estimatesOverall VEVE analysisPatientsInfluenzaRespiratory illnessVaccine-preventableInterim Estimates of 2023–24 Seasonal Influenza Vaccine Effectiveness — United States
Frutos A, Price A, Harker E, Reeves E, Ahmad H, Murugan V, Martin E, House S, Saade E, Zimmerman R, Gaglani M, Wernli K, Walter E, Michaels M, Staat M, Weinberg G, Selvarangan R, Boom J, Klein E, Halasa N, Ginde A, Gibbs K, Zhu Y, Self W, Tartof S, Klein N, Dascomb K, DeSilva M, Weber Z, Yang D, Ball S, Surie D, DeCuir J, Dawood F, Moline H, Toepfer A, Clopper B, Link-Gelles R, Payne A, Chung J, Flannery B, Lewis N, Olson S, Adams K, Tenforde M, Garg S, Grohskopf L, Reed C, Ellington S, Collaborators C, Collaborators C, Lauring A, Arndorfer J, Bride D, Peltan I, Mohr N, Hager D, Prekker M, Mohamed A, Johnson N, Steingrub J, Khan A, Busse L, Duggal A, Wilson J, Qadir N, Mallow C, Kwon J, Exline M, Shapiro N, Columbus C, Vaughan I, Mosier J, Safdar B, Harris E, Chappell J, Stewart L, Swan S, Piedra P, Sahni L, Englund J, Zerr D, Hickey R, Williams J, Rohlfs C, Schlaudecker E, Dosdos D, Moffatt M, Schuster J, Weltmer K, Szilagyi P, Curley T, Mills J, Faryar K, Salata R, Geffel K, Nowalk M, Murthy K, Rose S, Smith M, Wickersham B, Williamson B, Bontrager N, Williams O, Kramer J, Nordstrom L, Monto A, Vaughn I, Dickerson M, McLean C, Noble E, Ray C, Sumner K, Essien I, Fletcher L, Heaton P, Kane S, McEvoy C, Thapa S, Vazquez-Benitez G, Bezi C, Contreras R, Davis G, Lewin B, Mahale P, Patrick R, Qian L, Rayens E, Reyes I, Ryan D, Salas S, Sy L, Yeh M, Zeng X, Fireman B, Goddard K, Hansen J, Jacobson K, Timbol J, Zerbo O, Dunne M, Zhuang Y. Interim Estimates of 2023–24 Seasonal Influenza Vaccine Effectiveness — United States. MMWR Morbidity And Mortality Weekly Report 2024, 73: 168-174. PMID: 38421935, PMCID: PMC10907036, DOI: 10.15585/mmwr.mm7308a3.Peer-Reviewed Original ResearchConceptsVaccine effectivenessInfluenza vaccineInfluenza virus infectionInfluenza-associated hospitalizationsAnnual influenza vaccinationSeasonal influenza vaccineTest-negative case-control study designCase-control study designOutpatient visitsInfluenza VEInfluenza BInfluenza seasonInfluenza APediatric patientsInfluenzaVirus infectionOutpatient settingMonthsVaccinePatientsStudy designHospitalAdultsVisitsUnited States
2023
Vaccine Effectiveness Against Influenza A–Associated Hospitalization, Organ Failure, and Death: United States, 2022–2023
Lewis N, Zhu Y, Peltan I, Gaglani M, McNeal T, Ghamande S, Steingrub J, Shapiro N, Duggal A, Bender W, Taghizadeh L, Brown S, Hager D, Gong M, Mohamed A, Exline M, Khan A, Wilson J, Qadir N, Chang S, Ginde A, Mohr N, Mallow C, Lauring A, Johnson N, Gibbs K, Kwon J, Columbus C, Gottlieb R, Raver C, Vaughn I, Ramesh M, Johnson C, Lamerato L, Safdar B, Casey J, Rice T, Halasa N, Chappell J, Grijalva C, Talbot H, Baughman A, Womack K, Swan S, Harker E, Price A, DeCuir J, Surie D, Ellington S, Self W, Calhoun N, Murthy K, Cravens J, Herrick J, McKillop A, Hoffman E, Graves A, Zayed M, Smith M, Scott B, Health W, Fisher T, Hurutado-Rodriguez M, Kruse T, Dunkley S, Perez G, Bychkowski A, Grefsrud T, Calhoun N, Murthy K, Herrick J, Smith M, Steingrub J, Kozikowski L, De Souza L, Ouellette S, Shapiro N, Bolstad M, Coviello B, Ciottone R, Devilla A, Grafals A, Higgins C, Ottanelli C, Redman K, Scaffidi D, Weingart A, Surie D, McMorrow M, DeCuir J, Lewis N, Harker E, Ellington S, Mehkri O, Mitchell M, Griffith Z, Brennan C, Ashok K, Poynter B, Duggal A, Busse L, Lohuis C, Stanley N, Zhang S, Prekker M, Frosch A, Hendrickson A, Douglas S, Hurreh K, Peltan I, Smith C, Marshall H, Hager D, Ali H, Phan M, Gong M, Mohamed A, Nair R, Chen J, Exline M, Karow S, Khan M, So M, Snyder C, Swoope G, Smith D, Lee B, Rasul A, Pathak M, Lewald Z, Wilson R, Khan A, Peña J, Briceno G, Ahmed C, Martinez J, Pocius E, Oh M, Hyde J, Gause S, Wilson J, Gordon A, Perez C, Lau L, Bekiroglu I, Tran C, Frankel T, Garner O, Chandrasekaran S, Ginde A, Douin D, Martinez A, Huynh D, Steinwand A, Sullivan A, Withers C, Mohr N, Zepeski A, Nassar P, Landers S, Nielsen K, Briggs N, Fairfield C, Peebles A, Mallow C, Rivas C, Martin E, Monto A, Lauring A, McSpadden E, Truscon R, Kaniclides A, Thomas L, Bielak R, Valvano W, Fong R, Fitzsimmons W, Blair C, Gilbert J, Papalambros L, Holz A, Johnson N, Srinivasan V, Crider C, Steinbock K, Paulsen T, Anderson L, Self W, Talbot H, Grijalva C, Jones I, Halasa N, Chappell J, Womack K, Rhoads J, Baughman A, Kampe C, Johnson J, Swan S, Johnson C, Zhu Y, Rice T, Casey J, Stubblefield W, Zhu Y, Short L, Ezzell L, Whitsett M, McHenry R, Hargrave S, Blair M, Luther J, Pulido C, Peterson B, Files D, Gibbs K, Landreth L, Hicks M, Parks L, Kwon J, Parikh B, McDonald D, Samuels C, Vogt L, O’Neil C, Valencia A, Hink T, Bychkowski A, Dunkley S, Fisher T, Grefsrud T, Hurutado-Rodriguez M, Perez G, Beney K, Jayaprakash R, Koneru S, Lava J, Pinderi Z, Resk M, Goyal A, DeLamielleure L, Kosover M, Brokowski C. Vaccine Effectiveness Against Influenza A–Associated Hospitalization, Organ Failure, and Death: United States, 2022–2023. Clinical Infectious Diseases 2023, 78: 1056-1064. PMID: 38051664, PMCID: PMC11487098, DOI: 10.1093/cid/ciad677.Peer-Reviewed Original ResearchInfluenza-associated hospitalizationsVaccine effectivenessOrgan failureInfluenza vaccineSevere acute respiratory syndrome coronavirus 2Current season influenza vaccinationAcute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Influenza-associated outcomesInvasive mechanical ventilationAcute respiratory illnessSentinel Surveillance NetworkTest-negative designSyndrome coronavirus 2Close antigenic matchInfluenza vaccinationRespiratory failureRenal failureInfluenza seasonMechanical ventilationOrgan supportSupplemental oxygenRespiratory illnessCoronavirus 2Influenza circulation1108. Severity of Illness among Adults Hospitalized with Respiratory Syncytial Virus Compared with COVID-19 and Influenza — IVY Network, 25 Hospitals, 20 U.S. States, January 31, 2022 – April 11, 2023
Yuengling K, Surie D, DeCuir J, Zhu Y, Gaglani M, Ginde A, Gibbs K, Prekker M, Mohamed A, Johnson N, Peltan I, Bender W, Mallow C, Kwon J, Lauring A, Columbus C, Vaughn I, Safdar B, Chappell J, Baughman A, Swan S, Johnson C, McMorrow M, Self W, Martin E. 1108. Severity of Illness among Adults Hospitalized with Respiratory Syncytial Virus Compared with COVID-19 and Influenza — IVY Network, 25 Hospitals, 20 U.S. States, January 31, 2022 – April 11, 2023. Open Forum Infectious Diseases 2023, 10: ofad500.081. PMCID: PMC10678102, DOI: 10.1093/ofid/ofad500.081.Peer-Reviewed Original ResearchInvasive mechanical ventilationAcute respiratory illnessAdvanced respiratory supportSARS-CoV-2Respiratory supportRespiratory illnessCOVID-19Use of IMVHigh-flow nasal cannulaMultivariable logistic regression modelAsahi Kasei PharmaMedical condition categoriesSeverity of RSVFlow nasal cannulaInfluenza-associated hospitalizationsNon-invasive ventilationShortness of breathSeverity of illnessRespiratory syncytial virusSevere respiratory illnessGrant/research supportChi-square testLogistic regression modelsPrevalence of RSVMedian age