2002
Pseudomonas aeruginosa ExoT Acts In Vivo as a GTPase-Activating Protein for RhoA, Rac1, and Cdc42
Kazmierczak B, Engel J. Pseudomonas aeruginosa ExoT Acts In Vivo as a GTPase-Activating Protein for RhoA, Rac1, and Cdc42. Infection And Immunity 2002, 70: 2198-2205. PMID: 11895987, PMCID: PMC127837, DOI: 10.1128/iai.70.4.2198-2205.2002.Peer-Reviewed Original Research
2001
Rho GTPase activity modulates Pseudomonas aeruginosa internalization by epithelial cells
Kazmierczak B, Jou T, Mostov K, Engel J. Rho GTPase activity modulates Pseudomonas aeruginosa internalization by epithelial cells. Cellular Microbiology 2001, 3: 85-98. PMID: 11207623, DOI: 10.1046/j.1462-5822.2001.00091.x.Peer-Reviewed Original ResearchConceptsRho-GTP levelsP. aeruginosa internalizationRho familyEpithelial cellsGTP levelsRho-specific inhibitorRho family GTPasesC3 ADP-ribosyltransferaseRho GTPase activityPathogen Pseudomonas aeruginosaGram-negative pathogen Pseudomonas aeruginosaMadin-Darby canine kidney cellsPseudomonas aeruginosa internalizationCanine kidney cellsNative RhoActive alleleBacterial internalizationGTPase activityP. aeruginosa strain PA103Fusion constructsADP-ribosyltransferaseLatrunculin A.Active Rac1Bacterial uptakeHeLa cells