1991
Inherited Hepatic Enzyme Defects as Candidates for Liver-Directed Gene Therapy
Horwich A. Inherited Hepatic Enzyme Defects as Candidates for Liver-Directed Gene Therapy. Current Topics In Microbiology And Immunology 1991, 168: 185-200. PMID: 1893777, DOI: 10.1007/978-3-642-76015-0_9.Peer-Reviewed Original Research
1990
THE EFFECTS OF EARLY TREATMENT OF HEREDITARY TYROSINEMIA TYPE I IN INFANCY BY ORTHOTOPIC LIVER TRANSPLANTATION
Flye M, RIELY C, HAINLINE B, SASSA S, GUSBERG R, BLAKEMORE K, BARWICK K, HORWICH A. THE EFFECTS OF EARLY TREATMENT OF HEREDITARY TYROSINEMIA TYPE I IN INFANCY BY ORTHOTOPIC LIVER TRANSPLANTATION. Transplantation 1990, 49: 916-921. PMID: 2336709, DOI: 10.1097/00007890-199005000-00017.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid Metabolism, Inborn ErrorsHumansHydrolasesInfantLiver TransplantationPorphobilinogen SynthaseTime FactorsTyrosineConceptsOrthotopic liver transplantationLiver transplantationMedical therapyHereditary tyrosinemiaEarly liver transplantationMinimal perioperative complicationsWeeks of ageTyrosinemia type IPerioperative complicationsRapid institutionPoor prognosisNormal dietEarly treatmentMetabolic disordersTransplantationPrompt clearanceAbnormal metabolitesHydrolase deficiencyInfantsMental alertnessProgressive growthTherapyType ITyrosinemiaBiochemical responses