2024
Cross-Sectional Analysis of Infant Diet, Outcomes, Consumer Behavior and Parental Perspectives to Optimize Infant Feeding in Response to the 2022 U.S. Infant Formula Shortage
Damian-Medina K, Cernioglo K, Waheed M, DiMaggio D, Porto A, Smilowitz J. Cross-Sectional Analysis of Infant Diet, Outcomes, Consumer Behavior and Parental Perspectives to Optimize Infant Feeding in Response to the 2022 U.S. Infant Formula Shortage. Nutrients 2024, 16: 748. PMID: 38474876, PMCID: PMC10934383, DOI: 10.3390/nu16050748.Peer-Reviewed Original ResearchConceptsSpecialty formulasLactation supportPremature infant formulaBanked donor milkPostpartum lactation supportCow's milk formulaOptimal infant feedingInfant formula shortageInfant formulaCross-sectional analysisInfant dietHealthcare providersDonor milkLactation educationInfantsParents' perspectivesMilk formulaInfant feedingRetrospective surveyPurchase formulaHealthcareHelpfulness scoresSpecialtyOutcomesParents
2023
Nutrition Content of Young Child Formulas
Du N, DiMaggio D, Porto A. Nutrition Content of Young Child Formulas. Journal Of Pediatric Gastroenterology And Nutrition 2023, 76: 512-516. PMID: 36720107, DOI: 10.1097/mpg.0000000000003712.Peer-Reviewed Original ResearchConceptsYoung child formulasChild formulaInfant Formula ActPercent of infantsHealth care providersYears of ageNutrient recommendationsToddler milkPediatric GastroenterologyChildren 12Healthy childrenChildren 0Care providersNutritional recommendationsOlder infantsAmerican AcademyInfantsEuropean SocietySearch termsInternational recommendationsFormula recommendationsPediatrics statesToddler formulasSafety concernsMonths
2022
Nutritional and Safety Concerns of Infant Feeding Trends
DiMaggio DM, Du N, Porto AF. Nutritional and Safety Concerns of Infant Feeding Trends. Journal Of Pediatric Gastroenterology And Nutrition 2022, 74: 668-673. PMID: 35149650, DOI: 10.1097/mpg.0000000000003401.Peer-Reviewed Original ResearchConceptsDonor breast milkInfant feeding practicesBreast milkFeeding practicesInfant formulaMilk banksToddler formulasPercent of parentsSafety concernsHuman milk sharingPediatric gastroenterologistsPediatric GastroenterologyVoluntary electronic surveyInfant nutritionDrug AdministrationAmerican AcademySignificant health riskActive prescribersNorth American SocietyElectronic surveyAmerican SocietyMilk sharingInfantsClear guidelinesHealth risks
2021
Disparities in Telehealth Utilization Within Pediatric Gastroenterology
Puthenpura V, Du N, Hauptman L, Porto AF. Disparities in Telehealth Utilization Within Pediatric Gastroenterology. Journal Of Pediatric Gastroenterology And Nutrition 2021, 73: 217-222. PMID: 34016884, DOI: 10.1097/mpg.0000000000003167.Peer-Reviewed Original ResearchConceptsPediatric gastroenterology practiceSignificant decreased oddsMultivariate logistic regressionDecreased oddsTelephone visitsGastroenterology practicePediatric GastroenterologyVideo visitsLogistic regressionDistressed Communities IndexAmbulatory care visitsAdjusted odds ratioConfidence intervalsUse of telemedicineNon-Hispanic whitesRace/ethnicityCare visitsClinic visitsRetrospective studyOdds ratioTelehealth utilizationPublic insurancePrivate insuranceTelemedicine programVisits
2020
Non–FDA-Reviewed Imported European Formula Use Among Parents in Urban Pediatric Private Practice
Du N, DiMaggio DM, Williams JK, Leus I, Shabanova V, Song X, Porto AF. Non–FDA-Reviewed Imported European Formula Use Among Parents in Urban Pediatric Private Practice. Clinical Pediatrics 2020, 59: 566-572. PMID: 32146831, DOI: 10.1177/0009922820910819.Peer-Reviewed Original Research
2019
Comparison of Imported European and US Infant Formulas
DiMaggio DM, Du N, Scherer C, Brodlie S, Shabanova V, Belamarich P, Porto AF. Comparison of Imported European and US Infant Formulas. Journal Of Pediatric Gastroenterology And Nutrition 2019, 69: 480-486. PMID: 31107795, DOI: 10.1097/mpg.0000000000002395.Peer-Reviewed Original ResearchIgA-deficient humans exhibit gut microbiota dysbiosis despite secretion of compensatory IgM
Catanzaro JR, Strauss JD, Bielecka A, Porto AF, Lobo FM, Urban A, Schofield WB, Palm NW. IgA-deficient humans exhibit gut microbiota dysbiosis despite secretion of compensatory IgM. Scientific Reports 2019, 9: 13574. PMID: 31537840, PMCID: PMC6753154, DOI: 10.1038/s41598-019-49923-2.Peer-Reviewed Original ResearchConceptsGut microbiota compositionOverall microbial diversityHost-microbiota symbiosisSpecific microbial taxaGut microbial communityHuman gut microbiota compositionNon-redundant roleRRNA gene sequencingMicrobiota compositionMicrobial taxaMicrobial communitiesMicrobial diversityHealthy controlsSecretory IgAMucosal secretionsIgA-deficient humansBacterial cellsRelative abundanceAltered gut microbiota compositionGene sequencingDominant antibody isotypeDefined subsetsGut microbiota dysbiosisMicrobiotaMicrobiota dysbiosisRefractory Infantile Chronic Diarrhea and Failure to Thrive in a 6-Month-Old Boy With a Complex Past Medical History
Okafor D, AlRabadi L, Alper A, Jeffries L, McGrath J, Porto AF. Refractory Infantile Chronic Diarrhea and Failure to Thrive in a 6-Month-Old Boy With a Complex Past Medical History. Clinical Pediatrics 2019, 58: 707-710. PMID: 30788983, DOI: 10.1177/0009922819832034.Peer-Reviewed Original Research
2018
Assessment of Community Pediatric Providers’ Approach to a Child With Celiac Disease and Available Serological Testing Associated With a Large Tertiary Care Center
Alrabadi LS, Porto AF. Assessment of Community Pediatric Providers’ Approach to a Child With Celiac Disease and Available Serological Testing Associated With a Large Tertiary Care Center. Clinical Pediatrics 2018, 57: 1199-1203. PMID: 29667919, DOI: 10.1177/0009922818769453.Peer-Reviewed Original ResearchConceptsLarge tertiary care centerTertiary care centerEvidence-practice gapCeliac disease testingFalse-positive testsGastroenterology consultsGuideline recommendationsCeliac diseaseCare centerPatient concernsPediatric providersProvider practicesPositive testDisease testingAdditional testingDiet changeConsultsDiseaseCreating a Program for Junior Faculty Professional Development: A Tool Kit
Loyal J, Porto A, Camenga D. Creating a Program for Junior Faculty Professional Development: A Tool Kit. MedEdPORTAL 2018, 14: 10703. PMID: 30800903, PMCID: PMC6342391, DOI: 10.15766/mep_2374-8265.10703.Peer-Reviewed Original Research
2017
Updates in Infant Nutrition
DiMaggio DM, Cox A, Porto AF. Updates in Infant Nutrition. Pediatrics In Review 2017, 38: 449-462. PMID: 28972048, DOI: 10.1542/pir.2016-0239.Peer-Reviewed Original ResearchPrevalence and Patterns of Marijuana Use in Young Adults With Inflammatory Bowel Disease
Phatak UP, Rojas‐Velasquez D, Porto A, Pashankar DS. Prevalence and Patterns of Marijuana Use in Young Adults With Inflammatory Bowel Disease. Journal Of Pediatric Gastroenterology And Nutrition 2017, 64: 261-264. PMID: 27846066, DOI: 10.1097/mpg.0000000000001474.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseBowel diseaseYoung adultsAdverse effectsMarijuana useNeuropsychiatric adverse effectsPediatric IBD clinicsHalf of patientsPossible adverse effectsIBD clinicIBD therapyAbdominal painDisease activityIBD symptomsPoor appetiteMedical therapySymptom reliefComplete reliefSymptom improvementPatientsNonusers of marijuanaUse of marijuanaAnonymous questionnaireMedical marijuanaLegalization of marijuana
2016
Tissue Transglutaminase Levels Are Not Sufficient to Diagnose Celiac Disease in North American Practices Without Intestinal Biopsies
Elitsur Y, Sigman T, Watkins R, Porto AF, Leonard Puppa EL, Foglio EJ, Preston DL. Tissue Transglutaminase Levels Are Not Sufficient to Diagnose Celiac Disease in North American Practices Without Intestinal Biopsies. Digestive Diseases And Sciences 2016, 62: 175-179. PMID: 27778203, DOI: 10.1007/s10620-016-4354-4.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAutoantibodiesBiopsyCeliac DiseaseChildChild, PreschoolDuodenumFemaleGTP-Binding ProteinsHumansImmunoglobulin AInfantIntestine, SmallMaleNorth AmericaPredictive Value of TestsProtein Glutamine gamma Glutamyltransferase 2Retrospective StudiesSensitivity and SpecificityTransglutaminasesConceptsCeliac diseasePositive predictive valuePredictive valueIntestinal biopsiesIntestinal histologyTissue transglutaminase levelsRoutine clinical practiceNegative predictive valueNorth American childrenCeliac childrenPositive serologySymptomatic childrenAmerican guidelinesClinical practiceDifferent clinicsHigh titersDiseaseBiopsyTransglutaminase levelsTitersTissue transglutaminaseChildrenSerologyHistologyPresent study
2014
Lysosomal acid lipase deficiency: diagnosis and treatment of Wolman and Cholesteryl Ester Storage Diseases.
Porto AF. Lysosomal acid lipase deficiency: diagnosis and treatment of Wolman and Cholesteryl Ester Storage Diseases. Pediatric Endocrinology Reviews : PER 2014, 12 Suppl 1: 125-32. PMID: 25345094.Peer-Reviewed Original ResearchConceptsCholesteryl ester storage diseaseLysosomal acid lipaseWolman diseaseNon-alcoholic fatty liver diseaseCholesterol estersFatty liver diseaseNonspecific gastrointestinal symptomsStorage diseasePoor weight gainPotential medical therapiesPeripheral blood leukocytesEnzyme replacement therapyRecombinant human lysosomal acid lipaseAutosomal recessive disorderElevated transaminasesGastrointestinal symptomsMedical therapyLiver diseasePremature atherosclerosisRadiologic findingsReplacement therapyAdrenal glandCholesterol levelsLAL deficiencyLive births
2013
Cholesteryl Ester Storage Disease
Zhang B, Porto AF. Cholesteryl Ester Storage Disease. Journal Of Pediatric Gastroenterology And Nutrition 2013, 56: 682-685. PMID: 23403440, DOI: 10.1097/mpg.0b013e31828b36ac.Peer-Reviewed Original ResearchConceptsCholesteryl ester storage diseaseEarly diagnosisLysosomal acid lipaseStorage diseasePertinent laboratory testsLIPA gene mutationsEnzyme replacement therapyAcid lipaseTwo-thirdsEnglish-language publicationsGastrointestinal symptomsFatty liverSerum transaminasesCommon symptomsPediatric casesReplacement therapyCase reportLiver fibrosisFirst symptomsPubMed searchNew treatmentsSymptomsPatientsWolman diseaseGene mutations
2012
Management of chronic hepatitis C infection in children
Porto AF, Tormey L, Lim JK. Management of chronic hepatitis C infection in children. Current Opinion In Pediatrics 2012, 24: 113-120. PMID: 22157364, DOI: 10.1097/mop.0b013e32834eb73f.Peer-Reviewed Original ResearchConceptsChronic hepatitis C infectionHepatitis C infectionC infectionPeginterferon αAntiviral therapyLiver fibrosisGenotype 1Global public health burdenDevelopment of cirrhosisSustained virologic responseIndolent clinical courseLarge prospective studiesProgressive liver fibrosisPublic health burdenImportant clinical implicationsMajority of childrenAreas of controversyVirologic responseViral eradicationCombination regimensInfected childrenClinical courseProspective studyTreatment courseEarly treatment