2024
Is Clot Composition Associated With Cause of Stroke? A Systematic Review and Meta‐Analysis
Sujijantarat N, Templeton K, Antonios J, Renedo D, Koo A, Haynes J, Fathima B, Amllay A, Nowicki K, Huttner A, Giles J, Navaratnam D, Sansing L, Hebert R, King J, Matouk C. Is Clot Composition Associated With Cause of Stroke? A Systematic Review and Meta‐Analysis. Stroke Vascular And Interventional Neurology 2024, 4 DOI: 10.1161/svin.124.001426.Peer-Reviewed Original ResearchCause of strokeRed blood cellsWhite blood cellsBlood cellsMechanical thrombectomyCardioembolic groupHistological compositionMeta-analysisLow red blood cellQuantity of red blood cellsRandom-effects meta-analysisAcute ischemic strokeEffects meta-analysisEnglish-language articlesMean percentage differenceAdult patientsMEDLINE databaseCochrane LibraryClinical utilityIschemic strokeLanguage articlesPatientsPercentage differenceArteryCellular compositionLumbocaval Shunt for Idiopathic Intracranial Hypertension: A Technical Report and Case Series
Sujijantarat N, Koo A, Elsamadicy A, Antonios J, Renedo D, Haynes J, Fathima B, Theriault B, Chavez M, Amllay A, Nowicki K, Kanzler M, Jiang J, Shekar A, Hebert R, DiLuna M, Matouk C. Lumbocaval Shunt for Idiopathic Intracranial Hypertension: A Technical Report and Case Series. Neurosurgery Open 2024, 5: e00113. DOI: 10.1227/neuprac.0000000000000113.Peer-Reviewed Original ResearchIdiopathic intracranial hypertensionIntracranial hypertensionTreatment of idiopathic intracranial hypertensionManagement of idiopathic intracranial hypertensionMedical records of patientsAssessment of long-term outcomesHigh-pressure headachesMedian operative timeDifficult-to-manage patientsLow-pressure headacheCerebrospinal fluid shuntsElectronic medical records of patientsRecords of patientsFollow-up visitLong-term outcomesLumbar shuntDifficult-to-manage casesIntraoperative complicationsShunt revisionImprove headacheCase seriesEarly outcomesSurgical techniqueNeurosurgical managementOperative timeImprovement in cranial nerve palsies following treatment of intracranial aneurysms with flow diverters: Institutional outcomes, systematic review and study-level meta-analysis
Sujijantarat N, Antonios J, Renedo D, Koo A, Haynes J, Fathima B, Jiang J, Hengartner A, Shekhar A, Amllay A, Nowicki K, Hebert R, Gilmore E, Sheth K, King J, Matouk C. Improvement in cranial nerve palsies following treatment of intracranial aneurysms with flow diverters: Institutional outcomes, systematic review and study-level meta-analysis. Clinical Neurology And Neurosurgery 2024, 246: 108555. PMID: 39357321, DOI: 10.1016/j.clineuro.2024.108555.Peer-Reviewed Original ResearchStudy-level meta-analysisRate of improvementCN deficitsMeta-analysisIntracranial aneurysmsCN palsySystematic reviewFactors associated with recoveryPooled rateRandom-effects meta-analysisCranial nervesManual citation searchingEffects meta-analysisRate of clinical improvementCranial nerve palsyMechanism of injuryIncreased rate of improvementFlow diversionRare presenting symptomSymptomatic intracranial aneurysmsTreatment of intracranial aneurysmsCitation searchingPalsyNerve palsyRetrospective reviewHigher proceduralist stroke thrombectomy volume is associated with reduced inpatient mortality
Koo A, Renedo D, Ney J, Amllay A, Kanzler M, Stogniy S, Alawieh A, Sujijantarat N, Antonios J, Al Kasab S, Malhotra A, Hebert R, Matouk C, de Havenon A. Higher proceduralist stroke thrombectomy volume is associated with reduced inpatient mortality. Journal Of NeuroInterventional Surgery 2024, jnis-2024-022021. PMID: 39214687, DOI: 10.1136/jnis-2024-022021.Peer-Reviewed Original ResearchIn-hospital deathIn-hospital mortalityAcute ischemic strokeCut-pointsAbsolute risk of deathAssociated with lower oddsState Inpatient DatabasesFlorida State Inpatient DatabaseIn-hospital moralityRates of in-hospital mortalityDiagnosis of acute ischemic strokePrimary study outcomeRisk of deathStroke careOptimal cut-pointAssociated with reduced inpatient mortalityEndovascular thrombectomyRetrospective cohort studyLower oddsPotential confoundersAbsolute riskAcute ischemic stroke patientsInpatient mortalityCohort studyInpatient DatabaseO-035 Higher endovascular thrombectomy procedural volume is associated with reduced inpatient mortality
Koo A, Renedo D, Ney J, Amllay A, Kanzler M, Stogniy S, Nowicki K, Alawieh A, Sujijantarat N, Antonios J, Al Kasab S, Hebert R, Matouk C, de Havenon A. O-035 Higher endovascular thrombectomy procedural volume is associated with reduced inpatient mortality. 2024, a27.2-a28. DOI: 10.1136/jnis-2024-snis.35.Peer-Reviewed Original ResearchUse of a dedicated open transcarotid access system for neurovascular disease
Sujijantarat N, Renedo D, Antonios J, Koo A, Amllay A, Nowicki K, Cord B, Hebert R, de Havenon A, Sheth K, Petersen N, Matouk C. Use of a dedicated open transcarotid access system for neurovascular disease. Journal Of NeuroInterventional Surgery 2024, jnis-2024-021599. PMID: 38719442, DOI: 10.1136/jnis-2024-021599.Peer-Reviewed Original ResearchExtracranial carotid stenosisTranscarotid artery revascularizationNeurovascular diseasesCarotid stenosisDatabase of consecutive patientsNeurovascular pathologyTreatment of neurovascular diseasesAccess-related complicationsTreatment of neurovascular pathologiesOff-label useCarotid flow reversalConsecutive patientsRetrospective reviewIntracranial atherosclerotic diseasePeriprocedural complicationsEndovascular treatmentArtery revascularizationProcedural characteristicsArterial sheathCarotid diseaseAcademic centersIntracranial aneurysmsPatientsTranscarotid approachTransradial approachAngiographic evidence of an inadvertent cannulation of the marginal sinus following central line migration: illustrative case
Amllay A, Owolo E, Nowicki K, Sujijantarat N, Koo A, Antonios J, Renedo D, Matouk C, Hebert R. Angiographic evidence of an inadvertent cannulation of the marginal sinus following central line migration: illustrative case. Journal Of Neurosurgery Case Lessons 2024, 7: case23607. PMID: 38684119, PMCID: PMC11058405, DOI: 10.3171/case23607.Peer-Reviewed Original ResearchCentral venous catheterInternal jugular veinCatheter tip migrationTip migrationMalpositioned cathetersAbsence of contrast extravasationSinus cannulationTriple-lumen central venous catheterAortic valve replacementInadvertent cannulationCatheter malpositionContrast extravasationValve replacementSigmoid sinusImprove patient outcomesPosterior fossaEndovascular managementSevere complicationsVenous cathetersWeeks postinsertionPrompt managementAngiographic evidenceCatheter exchangeReduce morbidityInterventional suite167 Association Between Safety-net Hospital Status and Postoperative Outcomes Following ACDF or PCDF for Cervical Spondylotic Myelopathy
Elsamadicy A, Sayeed S, Craft S, Sherman J, Reeves B, Koo A, Khalid S, Lo S, Shin J, Mendel E, Sciubba D. 167 Association Between Safety-net Hospital Status and Postoperative Outcomes Following ACDF or PCDF for Cervical Spondylotic Myelopathy. Neurosurgery 2024, 70: 40-40. DOI: 10.1227/neu.0000000000002809_167.Peer-Reviewed Original ResearchCervical spondylotic myelopathyNon-routine dischargeSafety-net hospital statusSafety-net hospitalACDF cohortSpondylotic myelopathyPostoperative outcomesAdverse eventsMultivariate analysisPosterior cervical decompressionAnterior cervical discectomyImpact postoperative outcomesProportion of patientsNational Inpatient Sample databaseRetrospective cohort studyPredictors of prolonged LOSInpatient Sample databaseNon-SNHsElective ACDFCervical decompressionCervical discectomyStudy patientsIndependent predictorsAdult patientsACDF306 Endothelial Infiltrating Regulatory B Cells and NK T Cells Precipitate Inflammatory Cascade That Leads to Aneurysmal Rupture
Antonios J, Barak T, Gultekin B, Yalcin K, Adenu-Mensah N, Sujijantarat N, Koo A, Haynes J, Hebert R, Matouk C, Gunel M. 306 Endothelial Infiltrating Regulatory B Cells and NK T Cells Precipitate Inflammatory Cascade That Leads to Aneurysmal Rupture. Neurosurgery 2024, 70: 88-89. DOI: 10.1227/neu.0000000000002809_306.Peer-Reviewed Original ResearchRegulatory B cellsB cellsSentinel hemorrhageNK cellsInflammatory cascadeCytotoxic CD8 T cellsRecruitment of NK cellsCD8 T cellsAdjunctive immune therapyEndovascular coil embolizationCoordinated immune responseIntracranial aneurysm developmentImmune therapyRecurrent aneurysmsAneurysmal vessel wallT cellsCoil embolizationRuptured aneurysmsTime of ruptureAneurysm ruptureUnruptured aneurysmsInfiltrating populationPatient populationImmune responseAneurysm development308 Improvement in Cranial Nerve Neuropathies Following Treatment of Intracranial Aneurysms With Flow Diverters: Institutional Outcomes and Meta-analysis of Literature
Sujijantarat N, Antonios J, Koo A, Haynes J, Renedo D, Hebert R, Sheth K, King J, Matouk C. 308 Improvement in Cranial Nerve Neuropathies Following Treatment of Intracranial Aneurysms With Flow Diverters: Institutional Outcomes and Meta-analysis of Literature. Neurosurgery 2024, 70: 89-89. DOI: 10.1227/neu.0000000000002809_308.Peer-Reviewed Original ResearchIntracranial aneurysmsPooled rateMeta-analysisCranial nervesRate of clinical improvementNear total occlusionAneurysms treated with flow diversionCranial nerve neuropathyMonths of presentationFlow diversionAssociated with symptomatic improvementRare presenting symptomSymptomatic intracranial aneurysmsRate of improvementTreatment of intracranial aneurysmsRandom-effects meta-analysisMeta-analysis of literatureEffects meta-analysisOphthalmological outcomesCN deficitsRetrospective reviewAssociated with improvementsClinical improvementNerve neuropathySymptomatic improvementImpact of a quality improvement initiative and monthly multidisciplinary meetings on outcomes after posterior spinal fusion for adolescent idiopathic scoliosis
Hengartner A, Elsamadicy A, Jonnalagadda A, Craft S, Sherman J, Reeves B, Fernandez T, Hobbs J, Koo A, DiLuna M, Tuason D. Impact of a quality improvement initiative and monthly multidisciplinary meetings on outcomes after posterior spinal fusion for adolescent idiopathic scoliosis. Spine Deformity 2024, 12: 1043-1051. PMID: 38493442, DOI: 10.1007/s43390-024-00859-2.Peer-Reviewed Original ResearchPosterior spinal instrumented fusionPre-QI cohortAdolescent idiopathic scoliosisMultidisciplinary team meetingsProportion of patientsLength of stayPre-QITeam meetingsPost-QIPostoperative complicationsIdiopathic scoliosisQuality improvementQuality improvement initiativesPostoperative ambulationBenefits of enhanced recoveryMethodsThe medical recordsPain control protocolIntraoperative drain placementPosterior spinal fusionSpinal instrumented fusionQI implementationImprovement initiativesPatient careAmbulation statusDrain placementImpact of Procedure Time on First Pass Effect in Mechanical Thrombectomy for Anterior Circulation Acute Ischemic Stroke
Koo A, Reeves B, Renedo D, Maier I, Al Kasab S, Jabbour P, Kim J, Wolfe S, Rai A, Starke R, Psychogios M, Shaban A, Arthur A, Yoshimura S, Cuellar H, Grossberg J, Alawieh A, Romano D, Tanweer O, Mascitelli J, Fragata I, Polifka A, Osbun J, Crosa R, Park M, Levitt M, Brinjikji W, Moss M, Dumont T, Williamson R, Navia P, Kan P, Spiotta A, Sheth K, de Havenon A, Matouk C. Impact of Procedure Time on First Pass Effect in Mechanical Thrombectomy for Anterior Circulation Acute Ischemic Stroke. Neurosurgery 2024, 95: 128-136. PMID: 38483158, DOI: 10.1227/neu.0000000000002900.Peer-Reviewed Original ResearchAnterior circulation large vessel occlusion acute ischemic strokeAcute ischemic strokeLarge vessel occlusion acute ischemic strokeProcedure timeMechanical thrombectomyExcellent reperfusionClinical benefitIschemic strokeAnterior circulation acute ischemic strokeSuccess of mechanical thrombectomyModified Rankin Scale scoreRankin Scale scoreLogistic regression modelsNo significant differencePrimary study exposuresPrimary outcomeFunctional outcomesPotential confoundersStudy exposureThrombectomy devicesScale scoreThrombectomyReperfusionPatientsSignificant differenceAssociation of Malnutrition with Surgical and Hospital Outcomes after Spine Surgery for Spinal Metastases: A National Surgical Quality Improvement Program Study of 1613 Patients
Elsamadicy A, Havlik J, Reeves B, Sherman J, Craft S, Serrato P, Sayeed S, Koo A, Khalid S, Lo S, Shin J, Mendel E, Sciubba D. Association of Malnutrition with Surgical and Hospital Outcomes after Spine Surgery for Spinal Metastases: A National Surgical Quality Improvement Program Study of 1613 Patients. Journal Of Clinical Medicine 2024, 13: 1542. PMID: 38541767, PMCID: PMC10971134, DOI: 10.3390/jcm13061542.Peer-Reviewed Original ResearchNon-routine dischargeLength of stayImpact of malnutritionSpinal metastasesAdverse eventsMalnourished patientsNourished patientsSurgeons National Surgical Quality Improvement Program databaseSurgical treatment of spinal metastasesNational Surgical Quality Improvement Program databaseTreatment of spinal metastasesNational Surgical Quality Improvement Program studyQuality Improvement Program databaseRisk of postoperative complicationsMultivariate logistic regression analysisMetastatic spinal diseaseHospital length of stayProlonged length of stayAssociation of malnutritionRetrospective cohort studyPostoperative adverse eventsHealthcare resource utilizationAssessed patient demographicsExtradural spinal metastasisBaseline comorbidity burdenEndovascular Treatment of Acute Ischemic Stroke After Cardiac Interventions in the United States
de Havenon A, Zhou L, Koo A, Matouk C, Falcone G, Sharma R, Ney J, Shu L, Yaghi S, Kamel H, Sheth K. Endovascular Treatment of Acute Ischemic Stroke After Cardiac Interventions in the United States. JAMA Neurology 2024, 81: 264-272. PMID: 38285452, PMCID: PMC10825786, DOI: 10.1001/jamaneurol.2023.5416.Peer-Reviewed Original ResearchNational Institutes of Health Stroke ScaleNational Institutes of Health Stroke Scale scoreOdds of discharge homeDischarged homeIschemic strokeRate of endovascular thrombectomyMultivariate logistic regressionNational Inpatient Sample databaseHealth Stroke ScaleIntervention patientsInpatient Sample databaseMain OutcomesIntervention statusHospitalization of patientsPotential confoundersUS hospitalsEndovascular thrombectomyStroke patientsCohort studySecondary outcomesLogistic regressionCardiac interventionsStroke severityStroke ScaleGroup of hospitalized patientsAPOE ε4 and Intracerebral Hemorrhage in Patients With Brain Arteriovenous Malformation
Renedo D, Rivier C, Koo A, Sujijantarat N, Clocchiatti-Tuozzo S, Wu K, Torres-Lopez V, Huo S, Gunel M, de Havenon A, Sheth K, Matouk C, Falcone G. APOE ε4 and Intracerebral Hemorrhage in Patients With Brain Arteriovenous Malformation. JAMA Network Open 2024, 7: e2355368. PMID: 38363572, PMCID: PMC10873768, DOI: 10.1001/jamanetworkopen.2023.55368.Peer-Reviewed Original ResearchConceptsApolipoprotein E e4Participants of European ancestryRisk of intracerebral hemorrhageHigh risk of intracerebral hemorrhageCross-sectional studyUK BiobankEuropean ancestryHigh riskUs Research ProgramUK Biobank participantsInternational Classification of DiseasesAssociated with higher risk of ICHCross-sectional study of patientsAPOE e4 statusClassification of DiseasesApolipoprotein ENinth Revision and Tenth RevisionAssociated with higher riskIndividual-level dataMultivariate logistic regressionIntracerebral hemorrhage riskBrain arteriovenous malformationsIntracerebral hemorrhageBiobank participantsTenth Revision
2023
Influence of affective disorders on outcomes after suboccipital decompression for adult Chiari I malformation
Sherman J, Sayeed S, Craft S, Reeves B, Hengartner A, Fernandez T, Koo A, DiLuna M, Elsamadicy A. Influence of affective disorders on outcomes after suboccipital decompression for adult Chiari I malformation. Clinical Neurology And Neurosurgery 2023, 236: 108104. PMID: 38171050, DOI: 10.1016/j.clineuro.2023.108104.Peer-Reviewed Original ResearchHealthcare resource utilizationNon-routine dischargeLength of stayChiari I malformationAD cohortSuboccipital decompressionAffective disordersAdverse eventsPatient demographicsPostoperative eventsAdmission costsExtended LOSMean LOSNational Inpatient Sample databaseMultivariate logistic regression analysisAdult Chiari I malformationIncidence of syringomyeliaPerioperative adverse eventsChronic pulmonary diseaseICD-10-CM codesGreater proportionLogistic regression analysisComorbid affective disordersAdult patientsIndependent predictorsRacial/Ethnic Disparities Among Patients Undergoing Anterior Cervical Discectomy and Fusion or Posterior Cervical Decompression and Fusion for Cervical Spondylotic Myelopathy: A National Administrative Database Analysis
Elsamadicy A, Sayeed S, Sherman J, Craft S, Reeves B, Hengartner A, Koo A, Larry Lo S, Shin J, Mendel E, Sciubba D. Racial/Ethnic Disparities Among Patients Undergoing Anterior Cervical Discectomy and Fusion or Posterior Cervical Decompression and Fusion for Cervical Spondylotic Myelopathy: A National Administrative Database Analysis. World Neurosurgery 2023, 183: e372-e385. PMID: 38145651, DOI: 10.1016/j.wneu.2023.12.103.Peer-Reviewed Original ResearchCervical spondylotic myelopathyNon-routine dischargeHealthcare resource utilizationExtended hospital LOSHospital LOSWhite patientsHispanic patientsPatient raceNational Inpatient Sample databaseMultivariate logistic regression analysisGreater comorbidity burdenRacial/Ethnic DisparitiesAdministrative database analysisLogistic regression analysisRace/ethnicityACDF cohortComorbidity burdenPostoperative complicationsAdult patientsAdverse eventsPatient demographicsSpondylotic myelopathyIndependent predictorsSurgical outcomesBlack raceHigher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses
Renedo D, Acosta J, Koo A, Rivier C, Sujijantarat N, de Havenon A, Sharma R, Gill T, Sheth K, Falcone G, Matouk C. Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses. Stroke 2023, 54: 1538-1547. PMID: 37216451, PMCID: PMC10212531, DOI: 10.1161/strokeaha.122.041891.Peer-Reviewed Original ResearchConceptsHospital Frailty Risk ScoreRisk of strokeHighest Hospital Frailty Risk ScoresDate of consentFrailty Risk ScoreMendelian randomization analysisStroke riskRisk scoreRandomization analysisTime of enrollmentAvailable electronic health recordsMendelian randomizationElectronic health recordsLook-back periodIncident strokeDose-response wayFrailty statusHemorrhagic strokeMultivariable analysisStroke eventsObservational studyHigh riskFrailtySignificant associationSimilar associationSocioeconomic and Racial/Ethnic Disparities in Perception of Health Status and Literacy in Spine Oncological Patients
Elsamadicy A, Wang C, Reeves B, Sherman J, Craft S, Rajjoub R, Koo A, Hersh A, Pennington Z, Lo S, Shin J, Mendel E, Sciubba D. Socioeconomic and Racial/Ethnic Disparities in Perception of Health Status and Literacy in Spine Oncological Patients. Spine 2023, 48: 1107-1115. PMID: 37163649, DOI: 10.1097/brs.0000000000004712.Peer-Reviewed Original ResearchConceptsNon-White HispanicsOncology patientsHigh response rateWhite/CaucasianHealth statusHealth literacyWC patientsResponse rateICD-9/10-CM codesOwn general healthSocioeconomic statusBaseline health statusRacial/Ethnic DisparitiesCross-sectional studyRace/ethnicityExcellent/Severe fatigueGeneral healthOncological patientsBACKGROUND DATADisease processHealthcare costsPatientsMedical careEthnic disparitiesEffects of delayed ambulation following posterior spinal fusion for adolescent idiopathic scoliosis: a single institutional study
Hengartner A, David W, Reeves B, Craft S, Boroumand S, Clappier M, Hansen J, Fernandez T, Koo A, Tuason D, DiLuna M, Elsamadicy A. Effects of delayed ambulation following posterior spinal fusion for adolescent idiopathic scoliosis: a single institutional study. Spine Deformity 2023, 11: 1127-1136. PMID: 37093449, DOI: 10.1007/s43390-023-00693-y.Peer-Reviewed Original ResearchConceptsPosterior spinal fusionAdolescent idiopathic scoliosisSpinal fusionPostoperative complicationsRisk factorsIdiopathic scoliosisMultivariate stepwise logistic regressionOral pain medicationTotal hospital lengthTwenty-nine patientsMethodsThe medical recordsSingle institutional studyStepwise logistic regressionMajor academic institutionHospital lengthHospital stayNine patientsPain medicationUnplanned readmissionIntraoperative variablesPatient demographicsPostoperative outcomesRBC transfusionHealthcare utilizationOperative time