2016
CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits
Böhm UL, Prendergast A, Djenoune L, Nunes Figueiredo S, Gomez J, Stokes C, Kaiser S, Suster M, Kawakami K, Charpentier M, Concordet JP, Rio JP, Del Bene F, Wyart C. CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits. Nature Communications 2016, 7: 10866. PMID: 26946992, PMCID: PMC4786674, DOI: 10.1038/ncomms10866.Peer-Reviewed Original ResearchConceptsSpinal cordSpinal circuitsCentral pattern generatorCSF-cNsCerebrospinal fluid-contacting neuronsSpinal central pattern generatorVentral spinal cordLocomotor central pattern generatorCSF-contacting neuronsCentral canalSpinal bendingCordNeuronsMechanical stimuliMechanosensory organsOrgansSensory modalitiesAnimals
2015
State-Dependent Modulation of Locomotion by GABAergic Spinal Sensory Neurons
Fidelin K, Djenoune L, Stokes C, Prendergast A, Gomez J, Baradel A, Del Bene F, Wyart C. State-Dependent Modulation of Locomotion by GABAergic Spinal Sensory Neurons. Current Biology 2015, 25: 3035-3047. PMID: 26752076, DOI: 10.1016/j.cub.2015.09.070.Peer-Reviewed Original ResearchConceptsLocomotor central pattern generatorSensory neuronsCerebrospinal fluidCSF-cNsSpinal cordCentral pattern generatorSpinal sensory neuronsActivity of neuronsEntire nervous systemState-dependent modulationGABAergic synapsesSlow locomotionGlutamatergic interneuronsPremotor levelState-dependent mannerNervous systemFunctional connectivityRostrocaudal propagationNeuronsVertebrate spinal cordSelective activationCordEpithelial boundaryActivationFictive preparation